Navigation Links
New research findings on the brain's guardian cells

Researcher Johan Jakobsson and his colleagues have now published their results in Nature Communications.

"At present, researchers know very little about exactly how microglia work. At the same time, there is a lot of curiosity and high hopes among brain researchers that greater understanding of microglia could lead to entirely new drug development strategies for various brain diseases", says Johan Jakobsson, research group leader at the Division of Molecular Neurogenetics at Lund University.

What the researchers have now succeeded in identifying is a deviation in the structure of the microglia cells, which makes it possible to visualise them and study their behaviour. By inserting a luminescent protein controlled by a microscopic molecule, microRNA-9, the researchers can now distinguish the microglia and monitor their function over time in the brains of rats and mice.

It has long been known that microglia form the first line of defence of the immune system in diseases of the brain. They move quickly to the affected area and release an arsenal of molecules that protect the nerve cells and clear away damaged tissue. New research also suggests that microglia not only guard the nerve cells but also play an important role in their basic function.

"This represents a real step forward in technological development. Now we can view microglia in a way that has not been possible before. We and our colleagues now hope to be able to use this technique to study the role of the cells in different disease models, for example Parkinson's disease and stroke, in which microglia are believed to play an important role", explains Johan Jakobsson.


Contact: Johan Jakobsson
Lund University

Page: 1

Related medicine news :

1. UCLA Brain Injury Research Center gets NCAA funding for research on sports concussions
2. NIH awards $20 million over 5 years to train next generation of global health researchers
3. Researchers develop a new cell and animal model of inflammatory breast cancer
4. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
5. Sexually abused boys at risk for more unsafe sex: UBC research
6. Researchers Find Gene Mutations That May Be a Key to Autism
7. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
8. Researchers find evidence of banned antibiotics in poultry products
9. Presidential keynote address and new research highlights from the American Society of Pediatric Otolaryngology meeting
10. Scientific session and new research highlights
11. NJ stroke researchers report advances in spatial neglect research at AAN Conference
Post Your Comments:
(Date:10/13/2015)... , ... October 13, 2015 , ... ... a unique private messaging application, announced today a significant contract that will provide ... years. Independence plans to build on the growing success of its Relay program, ...
(Date:10/13/2015)... ... 2015 , ... A child without a healthy mouth is much more likely ... invisible aligner system, has joined with Global Dental Relief (GDR) to help ... treatment plan purchased, SmileCareClub will donate one clinic visit to a child in Kenya. ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... kind product that targets the unique health needs of new moms. Postnatal ... Pregnancy Association ( ), utilizes Nordic Naturals’ exclusive, new, ultra-concentrated omega-3 ...
(Date:10/13/2015)... ... , ... Tempe Dental Care, a leading Tempe dentists’ office, celebrates offering gentle, ... for more than 5 years. A leading cause of emergency room visits, school ... is not timely. , Sedation dentistry provides an anxiety-free dental experience ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... According to ... Rose suffered an orbital fracture when a teammate accidentally elbowed him in the left ... Rose's recent eye injury is just one of a series of setbacks, including a ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... 2015 Attracting mid- to large-sized medical device companies ... Baltimore into a major medical device ... Maryland Technology Enterprise Institute (Mtech) . ... place to support innovation hubs and a thriving medical device ... "This study is important because we believe Baltimore ...
(Date:10/13/2015)... Fla. , Oct. 13, 2015   Vigilant ... of solutions that aid in the early detection and ... has awarded Vigilant,s founder and CEO, Matthew H.J. ... Year Award, which recognizes an entrepreneur who has made ... life sciences industry in the leadership of ...
(Date:10/13/2015)... DURHAM, N.C. , Oct. 13, 2015   ... from the DESSOLVE I and II trials of its ... MiStent SES ® ) were presented at the ... held in San Francisco , October ... in interventional cardiovascular medicine. MiStent SES was designed to ...
Breaking Medicine Technology: