Navigation Links
New research confirms need for lung cancer testing
Date:2/2/2012

AURORA, Colo. (Feb. 2, 2012) Different kinds of lung cancer behave in different ways, suggesting they are fundamentally different diseases. According to a University of Colorado Cancer Center study published in Cancer, the official journal of the American Cancer Society, different subgroups of non-small cell lung cancer (NSCLC) show distinct patterns of spread in the body.

The study looked at 209 patients diagnosed with stage IV non-small cell lung cancer separated into four different molecular subgroups using testing performed by the University of Colorado Molecular Correlates Laboratory (CMOCO): those with epidermal growth factor receptor (EGFR) mutations, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations, anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements or a group without any of these abnormalities.

ALK positive lung cancer was strongly associated with cancers that spread to the linings around the heart and lungs (pericardial and pleural disease). Patients with ALK positive NSCLC were also predisposed to develop liver metastases as were those with an EGFR mutation when the different subgroups were compared.

"In the last few years we have been able to separate lung cancer into different molecular subtypes to help improve outcomes from specific targeted therapies. This study really confirms that these molecular subtypes are manifesting as different diseases in patients," said Robert Doebele, MD, PhD, lead author of the study and CU Cancer Center investigator.

Another University of Colorado study published in the same edition of Cancer drills down on how some of these different molecular subtypes of lung cancer are detected in the first place. Specifically, the study examined the companion diagnostic test for detecting the ALK positive lung cancer cases, called a fluorescence in situ hybridization (FISH) test. This test is used to select patients for treatment with crizoti
'/>"/>

Contact: Erika Matich
erika.matich@ucdenver.edu
303-524-2780
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... NJ (PRWEB) July 31, 2014 A cancer ... of people survive cancer and resume normal lives. This is ... Cancer Society, will affect one in seven American men but ... has a five-year survival rate of nearly 100% and a ... illness but most men diagnosed with the disease do not ...
(Date:7/31/2014)... its latest blog post, Best Drug Rehabilitation , which ... during a stay in rehab can make a big difference ... on nine secrets that addicts don’t want others to know. ... an addict from a mile away, and totally understand what’s ... Per Wickstrom . “However, take it from me: spotting ...
(Date:7/31/2014)... In its latest blog post, Best Drug ... family close by during a stay in rehab can make ... successful, is looking at 10 tips to help drug or ... is a lifelong process, and one that former addicts and ... compromise,” commented Best Drug Rehabilitation’s CEO Per Wickstrom . ...
(Date:7/31/2014)... 31, 2014 Thanks to its ... erythritol has long been used as a medium ... and monk fruit. However consistent, dependable sourcing of ... to meet food and beverage manufacturers’ increasing needs ... has launched GMO-free ErysweetTM Erythritol. , “Erysweet ...
(Date:7/31/2014)... Arizona (PRWEB) July 31, 2014 Nuanced ... announce the launch of the Nuanced Medical website ... created for the needs of the Medical Industry. , ... products and services for medical practices to meet continuously ... regulations being the HIPAA Act (Health Insurance Portability and ...
Breaking Medicine News(10 mins):Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 2Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 3Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 4Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 2Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 3Health News:New Best Drug Rehabilitation Blog Posts Looks at 10 Tips for Coping After Drug or Alcohol Rehab 2Health News:Steviva Ingredients Launches Erysweet Erythritol 2Health News:Nuanced Media, HIPAA Certified Agency, Launches Medical Web Design Service Website 2
... drugs , , WEDNESDAY, June 17 (HealthDay News) -- ... invade the nervous system of patients with a blood-borne ... the development of drugs that block these molecules and ... which primarily strikes children and adolescents, the bone marrow ...
... ... has been regularly engaging its healthcare provider customers in discussions about healthcare reform, the ... technology to address short and long-term healthcare objectives. , ... Stamford, CT (Vocus) June 18, 2009 -- ...
... Today the National Multiple Sclerosis Society - Wisconsin ... 2009 Physician Appreciation Award. The recognition commends Dr. Khatri ... and his research to treat it. , , ... honored to receive this recognition," says Dr. Khatri, medical ...
... 17 PRA International, a leading Clinical Research Organization, announces ... Information Association (DIA) meeting June 21 - 25 in San ... Executive Director of Medical Affairs will make a presentation entitled ... , In addition, Dr. Starkey and other PRA medical, ...
... , Redskins Kicker Shaun Suisham,s Foursome Takes First Place , ... 23rd Annual Maryland Golf Classic presented by Capital Carpets & ... kidney disease in the Washington DC area, a region that ... The tournament took place on June 15 at the picturesque ...
... quality improvement and affordable coverage for all Americans , ... Majority Leaders Howard Baker, Tom Daschle and Bob Dole, ... today released a bipartisan, budget-neutral framework for comprehensive health ... health coverage. The Leaders, Project on the State of ...
Cached Medicine News:Health News:Taking Aim at Relapse of Leukemia in Kids 2Health News:IVANS Hit Experts Available To Discuss the Dept. of HHS Recommendation Of “Meaningful Use” and How Potential Tighter Standards Will Impact the Provider Community 2Health News:IVANS Hit Experts Available To Discuss the Dept. of HHS Recommendation Of “Meaningful Use” and How Potential Tighter Standards Will Impact the Provider Community 3Health News:Aurora Physician Recognized for Multiple Sclerosis Care 2Health News:PRA International Experts Present at the 45th Annual DIA Meeting 2Health News:National Kidney Foundation's 23rd Annual Maryland Golf Classic Raises Funds to Fight Kidney Disease 2Health News:Former Senate Majority Leaders Baker, Daschle and Dole Release Bipartisan Framework for Comprehensive Health Reform 2Health News:Former Senate Majority Leaders Baker, Daschle and Dole Release Bipartisan Framework for Comprehensive Health Reform 3Health News:Former Senate Majority Leaders Baker, Daschle and Dole Release Bipartisan Framework for Comprehensive Health Reform 4
(Date:7/30/2014)... Wis. , July 30, 2014 ... developer, and marketer of over-the-counter (OTC) medicinal and ... the LipiGesic ® M name along with the ... be replaced with the trademarked name MigraPure ® ... color palette of PuraMed,s homeopathic, natural migraine pain ...
(Date:7/30/2014)... , July 30, 2014 /PRNewswire-iReach/ -- Transluminal Technologies ... medical device company, has announced today that they ... CD™ Vascular Closure Device. Velox CD™ provides a ... following percutaneous femoral procedures. The single size velox ... in size from 5F to 8F.  ...
(Date:7/30/2014)... 30, 2014 Reportlinker.com announces that a ... catalogue: mHealth and Home Monitoring – ... Executive summary mHealth can ... better outcomes, decreased costs and improved sustainability of ... is still in an early stage, but on ...
Breaking Medicine Technology:PuraMed BioScience Rebrands its Natural Migraine Relief Medication, LipiGesic M 2PuraMed BioScience Rebrands its Natural Migraine Relief Medication, LipiGesic M 3Transluminal Technologies receives CE Mark approval for velox CD(TM) vascular closure device 2mHealth and Home Monitoring - 6th Edition 2mHealth and Home Monitoring - 6th Edition 3mHealth and Home Monitoring - 6th Edition 4mHealth and Home Monitoring - 6th Edition 5mHealth and Home Monitoring - 6th Edition 6mHealth and Home Monitoring - 6th Edition 7mHealth and Home Monitoring - 6th Edition 8mHealth and Home Monitoring - 6th Edition 9mHealth and Home Monitoring - 6th Edition 10mHealth and Home Monitoring - 6th Edition 11
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
Medicine Products: