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New regulatory circuit identified for aggressive, malignant brain tumor
Date:4/7/2008

n GBM wherein it functions cooperatively with other INK4 family members to constrain inappropriate glial cell proliferation, concludes Dr. Chin.

This study also demonstrates that GTS can address one critical need in the development of a functional map of GBM genetic targets: namely, to prioritize those genomic alterations that are likely to be of importance from among those that are more likely to be bystanders of the cancer process, offers Dr.Brennan. Downstream functional validation of high probability candidates should yield novel GBM genes and potential targets for therapeutic intervention.


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Contact: Cathleen Genova
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