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New proteomics project to develop technology to detect liver disease via blood test
Date:4/18/2008

ch year die from HCV-induced liver damage and cancer. A percentage of infected people develop various levels of liver disease -- the worst requiring liver transplants -- but doctors have no way of telling who's most at risk.

PNNL's Smith is leading development of the new technology at DOE's Environmental Molecular Sciences Laboratory on the PNNL campus. In collaboration with UW's Michael Katze, Smith's group with use proteomics to compare blood and tissue samples from individuals who have advanced liver disease or are healthy to find proteins that indicate the potential for advanced illness.

The researchers' long term goal is to make such technology efficient and inexpensive enough for use in clinical settings. In addition, Smith's development plans include making the technology widely applicable to biomarker searches for other diseases.


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Contact: Mary Beckman
mary.beckman@pnl.gov
509-375-3688
DOE/Pacific Northwest National Laboratory
Source:Eurekalert

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