Navigation Links
New prognostic markers for gastric cancer patients
Date:5/20/2008

In standard clinical settings, DNA microarrays are currently unsuitable for routine use. Prognostic classification on formalin-fixed paraffin-embedded tissues is required. In this study, we looked for new molecular markers for identifying the prognosis of gastric cancer patients.

This study, performed by a team led by Professor Zhong-Sheng Zhao, is described in a research article to be published on April 7, 2008 in the World Journal of Gastroenterology.

The team identified that syndecan-1, E-cadherin and integrins highly correlated with each other as intracellular adhesion molecular complexes. We suggest the results of co-examination of them can be important indexes for the prognosis of gastric carcinoma. In the view of the authors, to date no clear mechanism has been found to explain the interaction of the three molecules, and no clinical research has been done to verify the findings.

Traditional clinicopathologic factors and several interesting molecules, including cell cycle regulation factors such as p27 or cyclin E, cell adhesion molecules such as E-cadherin, angiogenic factors such as vascular endothelial growth factor and placenta growth factor, oncogenes such as c-erbB2 and c-myc, and tumor suppressor genes such as p53, have been reported to correlate to the prognosis of gastric cancer patients. Cell adhesion is one of important steps in the multi-step process of gastric cancer pathogenesis.

Further research should collect more samples and emphasize the importance of studying multiple genetic alterations in concert.


'/>"/>

Contact: Jing Zhu
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Body Mass Index may serve as prognostic tool for advanced, aggressive breast cancers
2. Genomic Health Announces Oncotype DX(R) Provides Additional Prognostic Benefit in Patients Assessed With Adjuvant Online
3. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
4. Biomarkers Predict Heart Deaths
5. New Thomson Reuters Biomarkers Report Shines a Light on Revolutionary New Area of Drug Development
6. Researchers important markers of high risk of type 2 diabetes
7. New Heart Disease Markers Discovered
8. Biomarkers may reduce need for biopsies
9. Scientists: New technique identifies molecular biomarkers for disease
10. Large multicenter study suggests new genetic markers for Crohns disease
11. Fewer Steps Per Day Send Disease Markers Up
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... ... September 02, 2015 , ... Density measurement is used in ... sample handling makes density measurements more efficient and error-free. The new METTLER TOLEDO ... workflow and the advantages compared to manual sample handling. , The Evolution of ...
(Date:9/2/2015)... ... September 02, 2015 , ... Michael Elliot Media announces a crowdfunding ... actress as the primary love interest in the film. The campaign is being called ... affects how and what we think,” Michael Elliot, an award-winning screenwriter and CEO of ...
(Date:9/2/2015)... , ... September 02, 2015 , ... ... combining both naturopathic and allopathic medicine, opens its second location this week at ... features roughly 1000 square feet of lounge space for patients to relax while ...
(Date:9/2/2015)... (PRWEB) , ... September 02, ... ... the nation’s largest and fastest-growing interim clinical staffing companies, has completed a ... Heritage Group.         , BPOC and Heritage Group each offer extensive ...
(Date:9/2/2015)... , ... September 02, 2015 , ... ... announced today. The two day international investment and business conference will be hosted ... 2015 in Beijing China. The full-weekend networking conference will feature leading EB-5 industry ...
Breaking Medicine News(10 mins):Health News:New Video from METTLER TOLEDO Shows the Advantages of Sample Handling Automation in Density Determination 2Health News:New Video from METTLER TOLEDO Shows the Advantages of Sample Handling Automation in Density Determination 3Health News:Award-Winning Screenwriter Uses Crowdfunding Campaign to Change Hollywood’s Ideal of Beauty to Include PLUS-SIZE Women 2Health News:The Hydration Room Opens New Location In Laguna Beach, California 2Health News:The Hydration Room Opens New Location In Laguna Beach, California 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 4Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 2Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 3Health News:Medical Solutions Completes Recapitalization with Beecken Petty O’Keefe & Company and Heritage Group 4Health News:The 2015 China Overseas Investment and Entrepreneurship Summit (COIES) Announced 2
... into consideration the epidemic that is bird flu which is ... in aid to Turkey.// ,This follows a high level ... this bore fruit and according to latest reports World Bank ... aid. ,As said by Jurgen Voegele, Bank's Eastern Rural ...
... control measures to avoid infected poultry entering Germany from ... flu infection Turkish poultry// reported Germany Agricultural Minster Horst ... Germany to take stringent measures to avoid bird flu ... held in Berlin. German government will take strict legal ...
... say that the long winter might make people depressed and ... their winter blues//. ,Jane Kinyon, a clinical professor ... common to suffer from mild irritation and depression during the ... temperatures. But this should not dampen one’s spirit and discourage ...
... were to be reclassified again, according to campaigners. The UK’s ... the drug //is connected to mental disorders. This may result ... three years. It had been classified as a Class C ... to the use of the drug has to be conducted, ...
... the number of people suffering from stress and other related ... the stress levels // of 28 participants. ,They ... saliva cortisol levels are the best indicators of one’s stress ... after they spent their lunch hour viewing art. It was ...
... Oral and pharyngeal cancers are by far the leading ... these are not discovered until too late and thus ... sacrificing a large amount of tissue leading to ... collaborating with the American Dental Association (ADA) to build ...
Cached Medicine News:
(Date:9/2/2015)... 2, 2015  Boca Raton Regional Hospital,s ... performing ultra-minimally invasive left atrial appendage ligation for ... as Coumadin, Xarelto or Effient. Dr. Cartledge, who ... is one of a select group of surgeons ... microscopic incisions in order to seal off the ...
(Date:9/2/2015)... 2, 2015 According to a ... (Digital & Computed Radiography, Ultrasound, Computed & Optical Coherence ... Application (Oncology, Cardiology, Neurology) - Global Forecast to 2020", ... USD 2.8 Billion by 2020 growing at a CAGR ... Br owse 240 Tables and 44 F ...
(Date:9/2/2015)... , Sept. 2, 2015  RegeneRx Biopharmaceuticals, ... clinical-stage drug development company focused on tissue protection, ... Finkelstein , President and Chief Executive Officer, will ... Renshaw Global Investment Conference, sponsored by H.C. ... held September 8-10, 2015 at the St. Regis ...
Breaking Medicine Technology:Boca Regional Introduces Ultra-Minimally Invasive Surgical Procedure for Atrial Fibrillation Patients 2Boca Regional Introduces Ultra-Minimally Invasive Surgical Procedure for Atrial Fibrillation Patients 3Veterinary Imaging Market Worth USD 2.8 Billion by 2020 2Veterinary Imaging Market Worth USD 2.8 Billion by 2020 3Veterinary Imaging Market Worth USD 2.8 Billion by 2020 4Veterinary Imaging Market Worth USD 2.8 Billion by 2020 5RegeneRx to Present at Rodman & Renshaw Global Investment Conference 2RegeneRx to Present at Rodman & Renshaw Global Investment Conference 3
... WALTHAM, Mass., Sept. 30 Decision Resources, one ... focusing on pharmaceutical and healthcare issues, finds that ... will need to provide high-level information regarding the ... forego catchy and/or short taglines highlighting oral dosing. ...
... HERZELIYA, Israel, September 30 Medical device start-up,ActiViews ... led by 7 Health,Ventures. Previous investors: Ofer HiTech ... well. , ActiViews, founded ... Computer Tomography (CT), fluoroscopy and Magnetic Resonance Imaging ...
Cached Medicine Technology:Patient-Targeted Messaging for Emerging Multiple Sclerosis Agents Needs to Highlight Efficacy and Preservation of Quality of Life 2Patient-Targeted Messaging for Emerging Multiple Sclerosis Agents Needs to Highlight Efficacy and Preservation of Quality of Life 3
... Accurately tests for Nystagmus when ... 10" high by 8" diameter. Light ... ball bearings for effortless spin mechanism. ... from patient. Includes both Adult and ...
Diagnose dry eye, assess the effectiveness of permanent punctal occlusion, collagen - dissolvable in 3-5 days, all are 2 mm long. Sterile...
Clear Base Stand Magnifiers are ideal for any visual task that requires high magnification....
Contour design eyelid implants....
Medicine Products: