Navigation Links
New post-hoc analysis shows patients with type 2 diabetes undergoing intensification of insulin therapy experienced less nighttime hypoglycemia while being treated with Januvia (Sitagliptin) compared to placebo
Date:6/14/2014

WHITEHOUSE STATION, N.J., June 14, 2014 Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced results from a post-hoc analysis showing that patients with type 2 diabetes having treatment intensified with insulin glargine therapy while also being treated with JANUVIA (sitagliptin) 100 mg once-daily had a lower incidence of nighttime (nocturnal) hypoglycemia compared to patients also receiving placebo. Results were presented at the American Diabetes Association 74th Scientific Sessions.

"Type 2 diabetes is a progressive disease, so that over time many patients need to add insulin to their treatment regimens to maintain blood sugar control," said Peter Stein, M.D., vice president, Clinical Research for diabetes and endocrinology, Merck Research Laboratories. "Insulin therapy can lead to episodes of hypoglycemia that can occur either during the day or overnight while the patient is asleep. Hypoglycemia is troubling to both the patient and to the physician, so treatment approaches that can potentially lower the occurrence of hypoglycemiaoverall or overnightmay be important."

JANUVIA is indicated, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus. JANUVIA should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. JANUVIA has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk of developing pancreatitis while taking JANUVIA. JANUVIA is contraindicated in patients with a history of a serious hypersensitivity reaction to sitagliptin, such as anaphylaxis or angioedema.

Results of the original study:

The original clinical trial, "A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Study the Safety and Insulin-Sparing Efficacy of the Addition of Sitagliptin in Patients
'/>"/>

Contact: Pam Eisele
267-305-3558

Kim Hamilton
908-423-6831

Justin Holko
908-423-5088

Merck
Source:Eurekalert


Page: 1 2 3 4 5

Related medicine news :

1. Lung Cancer Screening Might Pay Off, Analysis Shows
2. SomaLogic publishes proteomic biomarker analysis of lung cancer tissue samples
3. Analysis Finds Clinical Trials Often Small, of Poor Quality
4. Zinc Pills May Shorten Colds, Analysis Suggests
5. Biochip-based device for cell analysis
6. Analysis will examine safety of in-hospital underwater births
7. Genome-wide analysis shows previously undetected abnormalities in parents of affected children
8. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
9. Meta-analysis: Interventions improve depression in cancer patients
10. Terrorism and the Olympics by-the-numbers: Analysis from UMD-based START
11. Genome analysis of brain tumors showing the way to new treatment strategies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... "When men sit down to use the toilet, ... water inside the bowl, the interior rim of the ... inventors from Naugatuck, and Bridgeport, Conn. "In order to ... , They developed the IPSAFE to prevent the penis ... and seat. This minimizes exposure to germs, which helps ...
(Date:8/23/2014)... York, New York (PRWEB) August 23, 2014 ... http://www.consumerinjurylawyers.com/wright-conserve-hip-replacement.html ) filed on behalf of individuals ... the Conserve hip replacement line continue to move ... of Georgia, Bernstein Liebhard LLP reports. According to ... established a bellwether trial program that would allow ...
(Date:8/23/2014)... 23, 2014 On Monday, August 18th, ... data breach suffered by Community Health Systems, which ... of 4.5 million records containing Personally Identifiable Information (PII) ... to Mandiant, who was engaged to investigate the incident, ... advanced group of cyber attackers based in China, who ...
(Date:8/23/2014)... The MPWMD Board of Directors voted on ... a sole source of water for commercial and industrial properties. ... Ron Brown of Archworks, LLC in Carmel, California. , ... time a water district in the State of California has ... AWGs at this time can now be used as ...
(Date:8/23/2014)... (PRWEB) August 23, 2014 Pixel Film Studios, ... announced today the release of ProIntro Vol.3, a customizable ... fresh and professional tile just by dragging ProIntro Vol.3 in ... "ProIntro Vol.3 is a definite time saver and i think ... pack with 30 beautifully designed titles made with Final Cut ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 2Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 3Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 4Health News:Historical Moment in the Monterey Peninsula, Brings Drought Relief Solution to California, with the Help of EcoloBlue and AWG Technology 2Health News:A new plugin was announced today, ProIntro Vol.3 from Pixel Film Studios for Final Cut Pro X 2
... Outline Program Details in Annapolis Media ... Event, ... in the United States will have used,an inhalant by the 8th grade. In ... for 6th graders inhalants are,the drug of choice, with use rates over twice ...
... With audience members cheering and,famous Chicago chefs watching ... for the finalists at Consorta,s Battle of the Hospital,Chefs. ... the organic cucumbers he,serves the patients at Saint Mary,s ... event,s Gold Chef Award, becoming the reigning champion of,chefs ...
... opportunity to engage in a discussion about health and ... lives. (Logo: http://www.newscom.com/cgi-bin/prnh/20070209/NYF043LOGO ) "These ... one in four adults lacking health coverage and one-third,concerned ... "With just one question asked about health care, ...
... for centuries, meditation has recently inspired research into ... to heart attack prevention. A painful, progressive ... a high risk of depressiondouble the risk of ... of psychological distress. Increasingly, RA patients are ...
... bilingual homes learned two similar-sounding words in a laboratory task ... homes where only one language is spoken. This difference, which ... be due to the fact that bilingual babies need to ... objects (often a word in each language) for a longer ...
... victory for the,families of small business owners and ... will improve accessibility of the State,Children,s Health Insurance ... Snowe (R-Maine) attached an amendment to the,legislation that ... more,children in the program. The provision requires the ...
Cached Medicine News:Health News:National Battle of the Hospital Chefs Cooks Up a Winner 2Health News:Post-Debate Statement from AARP Board Member Joyce Payne 2Health News:Meditation therapy for rheumatoid arthritis patients 2Health News:Meditation therapy for rheumatoid arthritis patients 3Health News:Babies raised in bilingual homes learn new words differently than infants learning one language 2Health News:Babies raised in bilingual homes learn new words differently than infants learning one language 3Health News:Bipartisan Bill Expands Health Care Access for Small Businesses 2
(Date:8/22/2014)... N.Y. , Aug. 22, 2014  Mark ... tomography (CT) imaging facility, is using the online ... and even 5D imaging to researchers and would-be ... launched, asks "What would YOU do if you ... possibility to researchers and explorers everywhere, from elementary ...
(Date:8/22/2014)... Aug. 22, 2014  WaferGen Bio-systems, Inc. (NASDAQ: WGBS) ... of units of common stock and warrants at a ... $20 million, prior to deducting underwriting discounts and commissions ... and warrants are immediately separable and will be issued ... begin trading on The NASDAQ Stock Market under the ...
(Date:8/21/2014)... AUSTIN, Texas , Aug. 21, 2014 /PRNewswire/ ... IT services company, announced today that it has ... Records (EMR) solution for Plastic Surgery and Dermatology ... provide even more value to healthcare practices using ... CEO of eRelevance Corporation. "Using information from the ...
Breaking Medicine Technology:Cornell's X-ray Imaging Lab Director Uses Kickstarter Campaign to "Democratize" Advanced 3D Imaging 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 3WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 4eRelevance Corporation Integrates with Nextech Electronic Medical Records 2
... Express Scripts, Inc. (Nasdaq: ESRX ) announced ... operations of $290.4 million and $1,275.8 million, or $0.59 and ... detailed in Table 4 were $0.82 and $2.97 per diluted ... "Through our unwavering focus on innovation, service and ...
... 2012  Endo Pharmaceuticals Holdings (Nasdaq: ENDP ) today ... corporate overview at the Cowen & Co. 32nd Annual Heath ... ET.  The conference will be held at the Boston Marriott ... and audio archive of the presentation will be available on ...
Cached Medicine Technology:Express Scripts Reports Fourth Quarter Results 2Express Scripts Reports Fourth Quarter Results 3Express Scripts Reports Fourth Quarter Results 4Express Scripts Reports Fourth Quarter Results 5Express Scripts Reports Fourth Quarter Results 6Express Scripts Reports Fourth Quarter Results 7Express Scripts Reports Fourth Quarter Results 8Express Scripts Reports Fourth Quarter Results 9Express Scripts Reports Fourth Quarter Results 10Express Scripts Reports Fourth Quarter Results 11Express Scripts Reports Fourth Quarter Results 12
... of Topics Covered: diagrams, full ... and differentials of a multitude ... vision loss, pupillary abnormalities, glaucoma, ... medications, cataracts, vision correction surgery, ...
... all those involved with healthcare decisions to ... latest evidence in their field of interest ... year as the volume of evidence increases. ... the best single source available for continually ...
Muscles Anatomy Flash Cards uses the time tested content and images from BryanEdwards.com....
The ideal on-the-spot reference for residents and practitioners seeking fast facts on fracture management....
Medicine Products: