Navigation Links
New photo 'op' for ovaries may solve some mysteries of infertility
Date:6/19/2008

CHICAGO -- What causes a woman's eggs to deteriorate in quality with age, and can that be reversed?

How does the ovary choose an egg -- out of a stash of roughly one million -- to release for ovulation? And can the ovary be influenced to pick a "good" quality egg rather than one with chromosomal damage?

These questions are much on the mind of fertility researcher Teresa Woodruff. Woodruff, director of the Center for Reproductive Research at Northwestern University's Feinberg School of Medicine, hopes to find the answers and, with them, new treatments for fertility disease and age-related infertility. Her research, funded by a new $6.5 million National Institutes of Health grant, has a novel approach.

Instead of measuring hormones and looking at genes -- the more traditional approaches to infertility research -- Woodruff and colleagues are studying the architecture and behavior of the ovaries.

"We're going to approach fertility disease from a new perspective," said Woodruff, the Thomas J. Watkins Professor of Obstetrics and Gynecology at the Feinberg School. "If we continue to look at the diseases of women's fertility traditionally, we're not going to solve the problems."

The inner daily workings of the ovary largely remain a mystery waiting to be solved.

"We don't understand how each follicle is selected to begin the process of ovulation," Woodruff said. "What caused this one to be selected when it's May and you're 19 years old while there might be one sitting right next to it quiescently for another 20 years before it is moved to the position where it can ovulate? Something controls or parcels those follicles over time so that you have enough from puberty until menopause."

There aren't many tools to help researchers examine the way ovaries function. Enter Frank Miller, M.D., who is developing a new imaging device to do exactly that.

"Ovaries are small and deep and they are more challenging to look at," said Miller, a professor of radiology at the Feinberg School and medical director of magnetic resonance imaging at Northwestern Memorial Hospital.

So he, along with colleagues in radiology, are designing a non-invasive magnetic resonance elastography device inspired by a larger one currently used for imaging livers.

Miller's new device will resemble a tiny drum, the size based on its future photo op with its subject - ovaries the size of walnuts. The device will generate sound waves ("like the sub-woofer system of a car," Miller says) to measure the rigidity of the ovaries.

Ovary rigidity is important to measure because it is one of the symptoms of polycystic ovary syndrome, a metabolic disease that is the leading cause of hormone-related infertility. In the syndrome, a woman's follicles do not function or ovulate normally.

"We hope that we will soon be able to understand more about age-related infertility and polycystic ovary syndrome," Woodruff said. "We're tackling problems that have been difficult to solve."


'/>"/>

Contact: Marla Paul
Marla-Paul@northwestern.edu
312-503-8928
Northwestern University
Source:Eurekalert

Related medicine news :

1. Photo: Tanger Outlet Center Shoppers Nationwide can Choose Pink to Fight Breast Cancer
2. Photo: Kyphon and the X-STOP(R) IPD(R) Procedure to be Featured on American Health Radio on Monday, September 24, 2007
3. Video and Photo: Leading CEOs Launch Alliance With American Red Cross to Strengthen Nations Preparedness for Disasters
4. Photos: New Survey Shows Many Successful Quit Smoking Attempts Made Without Advance Planning
5. Photos: Americas Chronically Ill Children Have New Hope with Hot Gift
6. Video and Photo: U.S. Department of Health & Human Services and Ad Council Join NFL to Combat Childhood Obesity
7. Photo: Introducing a New Line of Baby and Toddler Shirts that Can Help Protect Innocent Babies During Flu Season
8. Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
9. Photo: New York Goes Orange for Pumpkin Festival and Lupus Awareness Month
10. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
11. Photos: Drink Wine and Live Longer - 1907 Madiran and Plaimont Wines of Southwest France Sponsor the Launch of The Red Wine Diet
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2016)... ... ... ProBrand Reveal Volume 2 is a set of versatile and smooth logo reveals built exclusively ... can easily create a unique logo reveal in just a matter of minutes. Custom settings ... title presets to add a uniquely animated logo to any photos or videos. , ProBrand ...
(Date:4/30/2016)... ... April 30, 2016 , ... Create an abstract shape ... distort and manipulate three-dimensional shapes with ease all within Apple Motion . ... polygons, polygon texture animation, opacity texture animation, overall shape texture displacement, twist, camera ...
(Date:4/30/2016)... ... April 30, 2016 , ... Dr. Trevor Gardner, ... EMED, today signed a multifaceted agreement which will allow for the research and ... Department of Natural and Applied Sciences, Allied Health and Nursing will work together ...
(Date:4/29/2016)... ... April 30, 2016 , ... ... products, announces the Pick Up Springboard, an automotive invention that improves the storage ... industry is worth $162 billion," says Scott Cooper, CEO and Creative Director of ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... the Accreditation Council for Graduate Medical Education (ACGME) that it has received accreditation ... the first accreditation of three residency programs that Memorial is currently pursuing, including ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... , April 29, 2016  In the next ... to shift from systems dependent on CRTs monitors to ... of modality CRT Medical monitors and will automatically ... a host of foreseeable benefits to this technological ... existing modalities have to be replaced in order ...
(Date:4/29/2016)... 29, 2016 ReportsnReports.com adds ... market research report that provides an overview of ... at various stages, therapeutics assessment by drug target, ... and molecule type, along with latest updates, and ... key players involved in the therapeutic development for ...
(Date:4/29/2016)... ISELIN, New Jersey , April 29, 2016 ... Omnichannel Software Suite for Life Sciences, Product Development ... and Global Life Science Customer Base . ... healthcare solutions provider, today announced the acquisition of ... is a global leader in adaptive sales enablement ...
Breaking Medicine Technology: