Navigation Links
New photo 'op' for ovaries may solve some mysteries of infertility
Date:6/19/2008

CHICAGO -- What causes a woman's eggs to deteriorate in quality with age, and can that be reversed?

How does the ovary choose an egg -- out of a stash of roughly one million -- to release for ovulation? And can the ovary be influenced to pick a "good" quality egg rather than one with chromosomal damage?

These questions are much on the mind of fertility researcher Teresa Woodruff. Woodruff, director of the Center for Reproductive Research at Northwestern University's Feinberg School of Medicine, hopes to find the answers and, with them, new treatments for fertility disease and age-related infertility. Her research, funded by a new $6.5 million National Institutes of Health grant, has a novel approach.

Instead of measuring hormones and looking at genes -- the more traditional approaches to infertility research -- Woodruff and colleagues are studying the architecture and behavior of the ovaries.

"We're going to approach fertility disease from a new perspective," said Woodruff, the Thomas J. Watkins Professor of Obstetrics and Gynecology at the Feinberg School. "If we continue to look at the diseases of women's fertility traditionally, we're not going to solve the problems."

The inner daily workings of the ovary largely remain a mystery waiting to be solved.

"We don't understand how each follicle is selected to begin the process of ovulation," Woodruff said. "What caused this one to be selected when it's May and you're 19 years old while there might be one sitting right next to it quiescently for another 20 years before it is moved to the position where it can ovulate? Something controls or parcels those follicles over time so that you have enough from puberty until menopause."

There aren't many tools to help researchers examine the way ovaries function. Enter Frank Miller, M.D., who is developing a new imaging device to do exactly that.

"Ovaries are small and deep and they are more challenging to look at," said Miller, a professor of radiology at the Feinberg School and medical director of magnetic resonance imaging at Northwestern Memorial Hospital.

So he, along with colleagues in radiology, are designing a non-invasive magnetic resonance elastography device inspired by a larger one currently used for imaging livers.

Miller's new device will resemble a tiny drum, the size based on its future photo op with its subject - ovaries the size of walnuts. The device will generate sound waves ("like the sub-woofer system of a car," Miller says) to measure the rigidity of the ovaries.

Ovary rigidity is important to measure because it is one of the symptoms of polycystic ovary syndrome, a metabolic disease that is the leading cause of hormone-related infertility. In the syndrome, a woman's follicles do not function or ovulate normally.

"We hope that we will soon be able to understand more about age-related infertility and polycystic ovary syndrome," Woodruff said. "We're tackling problems that have been difficult to solve."


'/>"/>

Contact: Marla Paul
Marla-Paul@northwestern.edu
312-503-8928
Northwestern University
Source:Eurekalert

Related medicine news :

1. Photo: Tanger Outlet Center Shoppers Nationwide can Choose Pink to Fight Breast Cancer
2. Photo: Kyphon and the X-STOP(R) IPD(R) Procedure to be Featured on American Health Radio on Monday, September 24, 2007
3. Video and Photo: Leading CEOs Launch Alliance With American Red Cross to Strengthen Nations Preparedness for Disasters
4. Photos: New Survey Shows Many Successful Quit Smoking Attempts Made Without Advance Planning
5. Photos: Americas Chronically Ill Children Have New Hope with Hot Gift
6. Video and Photo: U.S. Department of Health & Human Services and Ad Council Join NFL to Combat Childhood Obesity
7. Photo: Introducing a New Line of Baby and Toddler Shirts that Can Help Protect Innocent Babies During Flu Season
8. Video and Photo: Tasigna(R) Receives US Approval Providing New Hope to Chronic Myeloid Leukemia Patients With Resistance or Intolerance to Existing Therapies
9. Photo: New York Goes Orange for Pumpkin Festival and Lupus Awareness Month
10. Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders
11. Photos: Drink Wine and Live Longer - 1907 Madiran and Plaimont Wines of Southwest France Sponsor the Launch of The Red Wine Diet
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... ... essential, and two new videos highlight the importance of correctly using a meat ... Ph.D., who has done extensive research on consumer food safety habits. Dr. Bruhn ...
(Date:6/23/2017)... Santa Monica, CA (PRWEB) , ... June 23, 2017 , ... ... PureLife as the endorsed amalgam separator supplier for CDA members. As part of the ... a reduced price of $99, saving more than $400 off the retail value. This ...
(Date:6/23/2017)... Dunmore, PA (PRWEB) , ... June 23, 2017 ... ... provides insurance management, financial planning, and related services to families and business owners ... for a charity drive to benefit senior citizens in the area. , Meals ...
(Date:6/23/2017)... ... June 23, 2017 , ... Moore Insurance, an ... with access to asset protection and financial planning services, is teaming up with ... the lives of children with cancer and other chronic diseases. , The For ...
(Date:6/22/2017)... ... June 22, 2017 , ... Groove Ring is excited to announce ... high performance silicon wedding bands and all-purpose rings. Whether you’re an athlete, adventurer, professional, ... designed just for you. , From the rock face to the auto shop, Groove ...
Breaking Medicine News(10 mins):
(Date:5/30/2017)... Therapix Biosciences Ltd. (Nasdaq: TRPX), a ... development of cannabinoid-based drugs, today announced that the ... three upcoming scientific and investor conferences in June: ... ... Wednesday, June 7 ...
(Date:5/24/2017)... , May 24, 2017  ivWatch LLC ... Equipment Manufacturer (OEM) Board to enable seamless integration ... patient monitoring systems, infusion pumps and other devices. ... will be able to help health care customers ... reduced risks related to IV therapy. ...
(Date:5/18/2017)... -- Two Bayer U.S. Pharmaceutical leaders received top awards from ... th Woman of the Year event ... mission of furthering the advancement and impact of women ... Powell-Steffen , senior director of brand activation and inside ... Howe , a regional business manager for New England ...
Breaking Medicine Technology: