Navigation Links
New personalized treatment options for cancer
Date:12/19/2011

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

The Centre for Personalised Cancer Medicine brings together a team of world-leading researchers with strengths in blood cancers and solid tumours, particularly breast, lung, sarcomas and melanoma.

Headed by Professor David Callen, the team will use tumour profiling and animal and cellular models to develop new drugs that target particular molecular changes in individual cancer patients.

"This centre reflects the trend towards a new, individualised approach to cancer medicine, taking into account genetic variations between people and their reaction to specific drugs," Professor Callen says.

"We will focus on improving the outcomes for cancer patients at all levels, from prevention through to treatment, survival, rehabilitation and palliative care, exploring novel and innovative approaches to cancer research.

"The big thrust at the moment is DNA sequencing. While it is still in the developmental stage, there are enormous resources being poured into this overseas and it looks like we will follow this lead in Australia."

The centre is already making headway in some areas, particularly in the treatment of sarcomas − rare malignant tumours which disproportionately affect young people and have a high mortality rate.

Dr Paul Neilsen, who oversees the Sarcoma Research Group, is collaborating with Royal Adelaide Hospital surgeon A/Prof Susan Neuhaus to trial new drugs on individual patient's tumours in a laboratory setting. "Currently these patients are treated with chemotherapy and radiotherapy but their outcomes are very poor and have not improved in the past decade," Dr Neilsen says.

"We have identified weak points in these tumours and are targeting them with new agents. The next step is to support
'/>"/>

Contact: Professor David Callen
david.callen@adelaide.edu.au
61-882-223-145
University of Adelaide
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New book by University of Louisville professor enables reader to develop personalized anti-depression plan
2. Northwestern to explore personalized medicine for scleroderma
3. Tumor-targeting compound points the way to new personalized cancer treatments
4. New and varied imaging techniques facilitate personalized medicine
5. Matching targeted therapies to tumors specific gene mutations key to personalized cancer treatment
6. Breast milk may provide a personalized screen of breast cancer risk
7. WSU researcher creates patented personalized therapy that causes cancer cells to kill themselves
8. IU Personalized Medicine Institute to develop targeted and individualized treatments
9. Tufts University calls for moderate approach to teaching personalized genomic testing
10. Personalized molecular therapy shows promising results for people with advanced lung cancer
11. Personalized vaccine for lymphoma patients extends disease-free survival by nearly 2 years
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... wealthy as the United States, it may come as a ... to adequate food due to lack of money or other ... at the University of Illinois using data from the National ... who are dealing with hunger are also facing negative health ... Americans over age 60 faced the threat of hungerthat translates ...
(Date:4/23/2014)... Oncotarget , explored tumour heterogeneity where different ... signatures within the same cancer. Such differences could ... strategies. , Firstly they confirmed the mutual exclusivity ... or BRAF mutation. Secondly, they found that lung ... that specific mutation present uniformly throughout the tumour, ...
(Date:4/22/2014)... Jersey Institute of Technology (NJIT) today to join ... of the New Jersey Innovation Institute (NJII), an ... business innovation through the leveraging of industry, government, ... Cory Booker, Panasonic Corp. of North America Chairman ... Kim Guadagno, New Jersey Secretary of Higher Education ...
(Date:4/22/2014)... 15 percent of all lung cancers are small ... often develop resistance to chemotherapy. However, researchers at ... new insights into the mechanisms leading to this ... , Chemotherapies work primarily by mediating B-cell lymphoma ... regulating cell death. Depending on their function, this ...
(Date:4/22/2014)... is the standard measurement for assessing glycemic control over ... are typically measured every few months in a laboratory, ... accurately estimates A1c using self-monitored blood glucose (SMBG) readings, ... ( DTT ), a peer-reviewed journal from Mary Ann ... the DTT website at http://www.liebertpub.com/dtt . ...
Breaking Medicine News(10 mins):Health News:More Americans in their golden years are going hungry 2Health News:Non-uniform genetic mutations identified in lung cancers could lead to targeted treatment 2Health News:Government and industry leaders herald launch of NJIT's New Jersey Innovation Institute 2Health News:Scientists pinpoint protein that could improve small cell lung cancer therapies 2
... "Occlusions in the retinal vein could not only make you loose ... veins is so painful that the eye may have to be ... new instrument that uses a plasma to shoot tiny bullets ... vessels that supply blood to the retina drain into a single ...
... market is currently dominated by the Mumbai based ... company, is planning to enter the anti-AIDS drugs ... and west Asia, S D Kaul, the company ... Aabacavir and Indinavir products in the Indian market ...
... that can have Complication as its other name. Among the ... be the foot ulcer, as damage can be severe enough ... ulcer, a boon in disguise would be a new device ... //Such an electrical stimulation would help in the healing of ...
... procedure widely used on knees can also repair damaged ... best known for repairing knee injuries, but it is ... it is a minimally invasive surgical technique it is ... relieve different ankle problems, including ligament damage, bone chips ...
... basis. One of these latest laser techniques is helpful in ... This degenerative condition cause blood vessels to grow underneath the ... ,Eye specialists have come up with a new therapy ... of damaging the retinal tissue. ,This is a two-step ...
... active ingredient is Acetaminophen is found effective in the ... temperature in people who have had a stroke, according ... ,Rise in the body temperature during the first few ... fever, has been linked to poorer outcomes including an ...
Cached Medicine News:Health News:Blocked viens block eye sight 2Health News:Arthroscopy for Ankles 2
(Date:1/15/2014)... N.J. , Jan. 15, 2014  Celsion Corporation (the "Company") ... has received commitments from institutional investors to purchase an ... stock in an at-the-market registered direct offering, led by ... entered into definitive purchase agreements with these investors pursuant ...
(Date:1/15/2014)... , Jan. 15, 2014  Humberto C. Antunes,  Galderma  worldwide ... from the Journal of Drugs in Dermatology ... Conference (ODAC). The event is January 17-20, 2014, at the Omni ... . The ODAC is a distinguished ...
(Date:1/15/2014)... Jan. 15, 2014  In an unprecedented effort to curb the spread ... and other transport vehicles, an advanced and portable UV germicidal lamp ... the first time. In order to prevent EMS ... pathogens, West Palm Beach Fire Rescue is ...
Breaking Medicine Technology:Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Superbugs No Longer Ride In Rescue Vehicles 2
... FRANCISCO, Calif., June 01, 2007,/PRNewswire-FirstCall/ -- Sunesis Pharmaceuticals, ... from ongoing clinical,studies of SNS-595 and SNS-032 at ... being held June 7-10, 2007 in Vienna,Austria. , ... Phase 1 clinical trial of SNS-595 in acute ...
... Zurich, June 1, 2007-Cytos Biotechnology AG is ... presentations of its novel,immunotherapeutic CYT003-QbG10 to treat ... were obtained,and will be presented in different ... Academy of Allergology and Clinical Immunology,(EAACI), taking ...
Cached Medicine Technology:Sunesis Pharmaceuticals to Present Data at the 12th Congress of the,European Hematology Association 2Sunesis Pharmaceuticals to Present Data at the 12th Congress of the,European Hematology Association 3CYT003-QbG10 to treat allergy to be presented at the Congress of,the European Academy of Allergology and Clinical Immunology,(EAACI), June 9-13, 2007 2
The Accuref 8001 allows you to measure much smaller pupils than conventional units and 3 step Target light adjuster ensures accurate results....
Sterile perfluorocarbon for intraocular Application....
Alcon offers medical grade perfluoropropane (SF6) intraocular gases for ophthalmological use....
Round knurled handle. Overall length 130 mm....
Medicine Products: