Navigation Links
New national study links asthma to allergies
Date:9/27/2007

Researchers at the National Institutes of Health (NIH) have found that more than 50 percent of the current asthma cases in the country can be attributed to allergies, with approximately 30 percent of those cases attributed to cat allergy.

It has long been debated whether people who develop asthma have a genetic propensity to develop allergies, or atopy, said Darryl C. Zeldin, M.D., a senior investigator at the National Institute of Environmental Health Sciences (NIEHS). This new research shows that 56.3 percent of asthma cases are attributed to atopy. Atopy is a condition that results from gene-environment interactions and can be measured by a positive skin test to allergens (or allergy causing substances in the environment).

The study, available online today in the Journal of Allergy and Clinical Immunology, was conducted by researchers at the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Allergy and Infectious Diseases, both parts of the NIH. The data come from the Third National Health and Nutrition Examination Survey (NHANES III), a nationally representative sample of the population of the United States.

Sensitization to cat appears to be a strong risk factor for asthma in this study, said Zeldin. Zeldin and his co-authors, however, point out that some research shows that exposure to cats, particularly early in life, may be a protective factor. We are not advocating parents get rid of pets, but if you suspect that you or your child might have cat allergies or get asthmatic-like symptoms, you should consult with a physician about the best course of action for your family, added Zeldin.

The NIH researchers looked at skin test data for ten allergens. A positive skin test reaction to cat allergens accounted for 29.3 percent of the asthma cases, followed by the fungus Alternaria at 21.1 percent and white oak at 20.9 percent. Each of 10 allergen-specific skin tests was strongly associated with asthma; however, after adjustment by a variety of subject characteristics and all the allergens, only skin tests to cat, Alternaria and white oak were independently and positively associated with asthma, said Peter Gergen, M.D., M.P.H, of NIAID's Division of Allergy, Immunology and Transplantation, a co-author on the paper.

Other allergens tested include: Ragweed, dustmites, Russian thistle, Bermuda grass, peanuts, perennial rye and german cockroach. Approximately 10,500 individuals participated in the skin testing. During these tests, skin was exposed to allergy-causing substances (allergens) and a positive test was determined by the size of the reaction on the skin.

This study tells us that allergy is a major factor in asthma, Gergen said. But this study also tells us is that there are many people who get asthma who dont have allergies. We need to do more research to understand what is causing the asthma that is not related to allergies.

This study confirms that the environment plays a major role in the development of asthma, said Zeldin. Given the complexity of this disease it wont be easy, but if we can prevent, block or reverse atopy, we could reduce a large proportion of asthma cases.


'/>"/>

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Related medicine news :

1. International community warns India on HIV situation
2. Mexico and US border attain a new outlook due to BiNational Sustainability Laboratory
3. National Lung Study in the process
4. Indian Nationals with Foreign Medical Degrees can now practice in India
5. Key step forward on International Health Rules
6. ICMR along with other International Research organisation with drug development for Neglected Diseases
7. International Osteoporosis Research Centre To Be Started In India.
8. Hepatitis B Vaccine To Be Included In National Immunization Programme
9. Indian hospitals require International Accreditation
10. International Conference On Malaria - Laveran To Genomics
11. UK Govt Says On Course For National Chlamydia Screening
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2017)... ... , ... More than half of Americans suffering from noise-induced hearing loss do ... that causes hearing loss? May 1 marks the beginning of Better Hearing & Speech ... well as schedule a hearing evaluation for anyone with concerns about his/her hearing. , ...
(Date:4/28/2017)... , ... April 28, 2017 , ... ... (The National Campaign) announces its support for the Access to Contraception for Women ... Shaheen (D-NH) and Rep. Jackie Speier (D-CA), will help to ensure that all ...
(Date:4/28/2017)... ... April 28, 2017 , ... Somnoware, a leading provider of ... which enables sleep physicians to create and edit their interpretation reports. This solution ... a familiar interface that does not require additional training to use. It also ...
(Date:4/28/2017)... ... ... affects much more than energy – it also has mental and physical benefits. According to ... time, which can increase the risk of having a car accident. , This week ... to help you sleep better and feel better:, , Turn off ...
(Date:4/28/2017)... ... April 28, 2017 , ... Ushio America proudly introduces ... an instant energy-saving solution for F32T8 fluorescent lamps on most instant-start and programmed-start ... 50,000 hour rated lamps utilize the existing electronic ballast, saving labor and maintenance ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017 Research and ... Technologies - Innovation Driven by Rapidly Expanding Injectables Market and Increasing ... their offering. ... for drug delivery technologies will rise from USD 20 Billion in ... Global Drug Delivery Technologies - Innovation Driven by Rapidly Expanding ...
(Date:4/20/2017)... , April 20, 2017 Research ... Pharmacogenomics Market Size, Market Share, Application Analysis, Regional Outlook, Growth ... report to their offering. ... The global pharmacogenomics market was valued at US$ 7,167.6 ... Mn by 2024, expanding at a CAGR of 5.6% from ...
(Date:4/19/2017)... Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), announces that it ... 2017 at the Sheraton Hotel in Toronto, Ontario ... the Company is scheduled to present on Tuesday, May 2 at ... Chairman of the Board, Tony Holler will also attend ... For more details ...
Breaking Medicine Technology: