Navigation Links
New myeloma-obesity research shows drugs can team with body's defenses
Date:5/2/2014

tion abnormally, including producing less adiponectin. What they produce more of, however, are fatty acids, and it is likely that myeloma cells can feed on these fatty acids.

"Synthesizing fatty acids is important for myeloma cells to build vital structures, including cell membranes, that enable them to keep on growing," Medina said.

Focusing on adiponectin led Dr. Medina's lab to protein kinase A or "PKA" a protein that, when activated by adiponectin, suppresses the fatty acids that myeloma cells need, leading to their demise.

The idea is to use the understanding of the pathways that adiponectin uses to kill myeloma cells to create a drug that would do the same thing.

"If we could pharmacologically suppress these fatty acid levels in obese myeloma patients, we could boost the effects of the chemotherapy that targets PKA or fatty acid synthesis, and potentially decrease the chemotherapeutic dose," Medina said. "Also, it would give your own body's protective measures more of a chance to work against the cancer."


'/>"/>

Contact: Elizabeth Allen
allenea@uthscsa.edu
210-450-2020
University of Texas Health Science Center at San Antonio
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers link age, general health and antidepressant use with eye disorders
2. St. Jude Childrens Research Hospital scientist elected to National Academy of Sciences
3. Researchers granted funding to explore novel lung cancer strategies
4. New UT Arlington research could improve pharmaceuticals testing
5. MS researchers find brain & cognitive reserve protect long-term against cognitive decline
6. UNC researchers discover master regulator role for little-known protein in cancer cells
7. The latest in scientific research in childrens health to be presented in Vancouver
8. CWRU researchers profile womens employment, caregiving workloads, effort and health
9. Stress research in therapy dogs reveals animals needs
10. Drug monitoring information improves regimen adherence, Carnegie Mellon researchers say
11. NIH center sets new goals for global health research and training
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... Barcelona, Spain Saturday 30 August 2014: Transvenous lead ... of cases according to data from the European Lead ... today at ESC Congress 2014 by Dr Maria Grazia ... Bongiorni said: "The number of cardiac implantable electronic devices ... advances in technology the number of complications has increased ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 Top10BestSEOHosting.com ... experienced researchers have announced that HostGator.com http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts ... the current market. Also, they has announced that ... webmasters. , Hostgator, one of the Top ... supplier of cheap Windows hosting, and it offers ...
(Date:8/30/2014)... Tulsa, OK (PRWEB) August 30, 2014 LiveStreamingFitness.com, ... as well as other healthy lifestyle resources, is proud to ... affordable nationwide resources for at home fitness solutions by ABC’s ... a recent featured story on ABC’s Good Morning America, “Live ... Now, you can streamline your day by streamlining your workout…to ...
(Date:8/30/2014)... McLeod's Sunset Park Auto Service , ... with strong ties to the community celebrates sixty years in ... they have been chosen by The Tampa Tribune’s ... , Tim McLeod’s father, Norris (most know him as ... Although his son, Tim runs the day to day, taking ...
(Date:8/30/2014)... August 30, 2014 Zensah®, the leader in ... Compression Leg Sleeve . The camo sleeves are the first ... collection. The camo line includes classic colors like army ... , Known as tibial stress syndrome, shin splints cause ... lower leg. Swollen and irritated muscles, stress fractures, or over ...
Breaking Medicine News(10 mins):Health News:Transvenous lead extraction clinically successful in 98 percent of cases 2Health News:Transvenous lead extraction clinically successful in 98 percent of cases 3Health News:Top10BestSEOHosting.com: HostGator.com Is The Best Windows Hosting Supplier 2Health News:LiveStreamingFitness.com is New Trend In Fitness 2Health News:McLeod's Sunset Park Auto Service Celebrates 60 Years Honored with Best of South Tampa 2Health News:Camo Compression Leg Sleeves Provide Shin Splint Relief for Runners 2
... culture play a role, expert contends, , WEDNESDAY, Sept. 30 ... complications of surgery, not just the rate of those complications, ... found. , The study, which included more than 84,000 people ... twofold difference in surgical deaths between hospitals with the lowest ...
... children don,t see their family dentist until they are well ... both dental and medical professionals. , That,s one of the ... conducted on behalf of Delta Dental Plans Association, the nation,s ... gain greater knowledge about the state of children,s oral health. ...
... The Sleep Center at Baylor University Medical Center at ... Sleep Medicine. The center at Baylor Dallas is one ... , "Accreditation provides formal recognition of our commitment ... from sleep disorders," said David L. Luterman, M.D., sleep ...
... by Weill Cornell Medical College researchers looks at the ... drink and use marijuana in combination. Among their findings: ... (smoking, drinking and marijuana), and that this manifested itself ... were shown to be central. Ambivalent or permissive attitudes ...
... The Drug ... and Risks of Medicinal Products in Regulatory Decisions from November 3- 5, 2009 in Bethesda, ... Horsham, PA (Vocus) ... and Drug Administration (USFDA) will host Assessing Benefits and Risks of Medicinal Products in ...
... ... is inviting all tailgating aficionados to grab a video camera and show the world their ... , ... 2009 -- http://www2.samsclub.com/tailgatechallenge , , , , ,It,s Simple - Upload to win ,With ...
Cached Medicine News:Health News:Surgical Deaths Linked to Handling of Complications 2Health News:Surgical Deaths Linked to Handling of Complications 3Health News:Delayed First Visit to Dentist Can Affect Children's Lifelong Oral Health 2Health News:Sleep Center at Baylor Dallas One of Select Centers in North Texas to Receive Accreditation 2Health News:Teen attitudes toward smoking linked to likelihood of drinking and using drugs 2Health News:Global Regulators to Discuss Benefit-Risk Approaches of Medicinal Products at DIA Workshop 2Health News:Global Regulators to Discuss Benefit-Risk Approaches of Medicinal Products at DIA Workshop 3Health News:Sam's Club Tailgate Challenge Video Contest: Show Sam's Club Your Best Tailgating Style for a Chance To Win a $1,000 Gift Card 2Health News:Sam's Club Tailgate Challenge Video Contest: Show Sam's Club Your Best Tailgating Style for a Chance To Win a $1,000 Gift Card 3
(Date:8/29/2014)... 2014 Research and Markets has ... Therapeutics Market & Pipeline Insight 2014" report to ... to prevent and eradicate the prevalence of cancer have ... confined to low specificity, safety and large number of ... a better solution. It has been discovered that peptides ...
(Date:8/29/2014)...  United Therapeutics Corporation (NASDAQ: UTHR ) ... District of New Jersey has ... Sandoz, Inc. regarding United Therapeutics, Remodulin ® product.  In ... U.S. Patent No. 6,765,117 is both valid and enforceable ... generic product until the expiration of that patent in ...
(Date:8/29/2014)... -- ChemImage will present a workshop focused on hyperspectral ... Science Society,s 22 nd International Symposium on ... .  Forensic Scientists will be in attendance ... can bring to examination procedures. ... Development at ChemImage, will host a workshop during ...
Breaking Medicine Technology:Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2District Court Decision Received In Remodulin Patent Case 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
For use with Snap-In Snap-Out-II tip inserts. Available in five styles, the Snap-In Snap-Out-II Laparoscopic Instrument Handles offer the broadest range available....
For use with Snap-In Snap-Out-II tip inserts. Available in five styles, the Snap-In Snap-Out-II Laparoscopic Instrument Handles offer the broadest range available....
Medicine Products: