Navigation Links
New mutation linked to non-Hodgkin's lymphoma
Date:11/1/2010

Some patients with non-Hodgkin lymphoma (NHL)a cancer of B cellsharbor a particular mutation in the gene encoding the receptor for B cell activating factor (BAFF), according to a paper published online on November 1 in the Journal of Experimental Medicine (www.jem.org). BAFF, a soluble protein needed for B cell survival and maturation, is elevated in the blood of some NHL patients and is associated with poor prognosis.

This BAFF-R mutation, identified by a team led by Anne Novak and Gail Bishop, generates a receptor that transmits stronger than normal signals, thus boosting B cell function.

Although present in fewer than 10% of the tumors analyzed in the study, this mutation provides further evidence of the importance of BAFF signaling in this dangerous malignancy.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Smart drug targets new mutation, dramatically shrinks aggressive sarcoma and lung cancer
2. Gene Mutations May Blunt Plavixs Effectiveness, Study Finds
3. Colorectal cancer patients with gene mutation show better response to cancer agent
4. Study finds women with triple negative breast cancer and BRCA mutations have lower risk of recurrence
5. Individual mutations are very slow to promote tumor growth
6. Preclinical inquiry into 1 mutation sheds light on addiction and a birth defect
7. U-M researchers identify gene mutation that causes rare form of deafness
8. DNA mutation rates raise curtain on cause of cancer
9. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
10. Gene mutation increases thromboembolism risk in women taking tamoxifen
11. Gene Mutations Offer Clues to Autoimmune Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... ... ... America Walks , a national advocacy organization that promotes walking and ... Pittsburgh Graduate School of Public Health , has been awarded a Walking College ... around the country to participate in a four-month training program designed to strengthen local ...
(Date:5/25/2016)... ... May 25, 2016 , ... "FCPX LUT Intense allows ... your footage," said Christina Austin - CEO of Pixel Film Studios. , With ... and easily add stylish color grades to their footage. A LUT is a Lookup ...
(Date:5/25/2016)... ... May 25, 2016 , ... Consumer access to organic foods and grower access ... maker of whole grain cereals and other plant-based foods, will introduce the first consumer ... winter wheat processed by Hesco/Dakota Organic Products. , The transitional designation means the cereal ...
(Date:5/25/2016)... ... 25, 2016 , ... Stern Environmental Group , of Secaucus, New Jersey, ... as Stern’s Real Time Monitoring (RTM) Device. Stern Environmental Group will sell ... industry, colleges for use in dormitories, shelters, and nursing homes for real time bedbug ...
(Date:5/24/2016)... ... 2016 , ... Sterling Global Products is launching a Kickstarter campaign focused on ... dispenser. The campaign kick-off video is located via this link https://youtu.be/WsO4qz2odco . The ... is to raise $1,000 per day for a total of $25,000. The funds will ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... , May 23, 2016 The World Health Organization ... device to include adolescents aged 13 years, and above. ... be offered for adult and adolescent males in the 14 ... . PrePex was the first male circumcision device to receive ... CEO, Eddy Horowitz said: " The expanded ...
(Date:5/23/2016)... 2016 Gamida Cell, a leader ... cancer and orphan genetic diseases, announced today it has ... from the Israel Innovation Authority (formerly the Office of ... and Industry. The mission of the Israel Innovation Authority ... including science and technology, while stimulating economic growth. ...
(Date:5/22/2016)... , May 23, 2016 ... develop its anti-fibrotic and anti-inflammatory compound DS102 in ... as in non-alcoholic steatohepatitis (NASH) patients. ... significantly sequestered in lung tissue and has bronchodilatory, ... after oral administration. The Company will publish further ...
Breaking Medicine Technology: