Navigation Links
New mutation linked to non-Hodgkin's lymphoma
Date:11/1/2010

Some patients with non-Hodgkin lymphoma (NHL)a cancer of B cellsharbor a particular mutation in the gene encoding the receptor for B cell activating factor (BAFF), according to a paper published online on November 1 in the Journal of Experimental Medicine (www.jem.org). BAFF, a soluble protein needed for B cell survival and maturation, is elevated in the blood of some NHL patients and is associated with poor prognosis.

This BAFF-R mutation, identified by a team led by Anne Novak and Gail Bishop, generates a receptor that transmits stronger than normal signals, thus boosting B cell function.

Although present in fewer than 10% of the tumors analyzed in the study, this mutation provides further evidence of the importance of BAFF signaling in this dangerous malignancy.


'/>"/>

Contact: Rita Sullivan
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related medicine news :

1. Smart drug targets new mutation, dramatically shrinks aggressive sarcoma and lung cancer
2. Gene Mutations May Blunt Plavixs Effectiveness, Study Finds
3. Colorectal cancer patients with gene mutation show better response to cancer agent
4. Study finds women with triple negative breast cancer and BRCA mutations have lower risk of recurrence
5. Individual mutations are very slow to promote tumor growth
6. Preclinical inquiry into 1 mutation sheds light on addiction and a birth defect
7. U-M researchers identify gene mutation that causes rare form of deafness
8. DNA mutation rates raise curtain on cause of cancer
9. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
10. Gene mutation increases thromboembolism risk in women taking tamoxifen
11. Gene Mutations Offer Clues to Autoimmune Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... June 23, 2017 , ... American Farmer, will feature Chr. Hansen, Inc ... to air fourth quarter 2017. American Farmer airs Tuesdays at 8:30aET on RFD-TV. Check ... founded Chr. Hansen in Denmark in 1874 after a groundbreaking discovery of how to ...
(Date:6/23/2017)... ... 2017 , ... Radabaugh & Associates, a locally owned firm ... in North Central West Virginia, is embarking on a cooperative charity drive with ... the region. , The Stepping Stones organization offers a series of personal development ...
(Date:6/22/2017)... California (PRWEB) , ... June 22, 2017 , ... Groove ... spread the word about their high performance silicon wedding bands and all-purpose rings. Whether ... are the active, silicone rings designed just for you. , From the rock face ...
(Date:6/22/2017)... Angeles, California (PRWEB) , ... June 22, 2017 , ... ... therapist Nira Rittenberg to a correspondent concerned about an apparent lack of oral hygiene ... Rittenberg, who specializes in geriatrics and dementia-related matters, suggests a number of steps, including ...
(Date:6/20/2017)... New York City (PRWEB) , ... June 20, 2017 , ... After months of negotiations, ... the QVC Network on Wednesday, June 21. , “Introducing our product on QVC ... opportunity for us to promote our travel pillow to more than 90 million homes in ...
Breaking Medicine News(10 mins):
(Date:6/10/2017)... K. Burchfield, DPM, is recognized by Continental Who,s Who as a ... Alabama . Dr. Burchfield serves as ... over 20 years of experience, as well as expertise in the ... "The podiatry professional ... to welcome you to his practice," the company,s website states. "We ...
(Date:6/8/2017)... 8, 2017  StatLab Medical Products ("StatLab" ... manufacturer of diagnostic supplies for the anatomic ... & Company LP ("Cressey & Company"), a ... growth-focused investment in the Company. Cressey & ... from selling shareholder, Prairie Capital, L.P., with ...
(Date:6/5/2017)... Kohll,s Pharmacy & Homecare is the first distributor of ... . The Raizer is a simple battery operated mobile ... an almost-standing position within a few minutes. The ... and does not require any extra effort besides a ... can operate it, and lightweight and portable so ...
Breaking Medicine Technology: