Navigation Links
New method to overcome multiple drug resistant diseases developed by Stanford researchers
Date:8/18/2008

rate and then waiting as the effective amount in the patients slowly dwindled until they could safely inject more. This approach results in a repeated pattern of rapid spikes in the amount of medication in the system, followed by slow declines until the next spike. Ideally, doctors would like the patient to be continually experiencing the maximum tolerable dosage to keep the pressure on the cancer cells, killing them off as quickly and as thoroughly as possible. The arginine transporter makes this possible.

Ovarian cancer was chosen as the subject cancer for this study in part because it commonly develops resistance to Taxol, but also because of a low long-term success rate in treating it. The American Cancer Society estimates that in the United States alone there will be 21,650 diagnoses of ovarian cancer this year and 15,500 deaths from it.

"Ovarian cancer has a drug [Taxol] that works pretty well in the beginning. Seventy or eighty percent of the patients have a response," Teng said. "But it fails at the end because drug resistance develops."

Further studies need to be done to demonstrate the safety of arginine transporters before they can be used in this application in humans, Wender and Teng said. But the researchers already have positive safety data from tests of arginine-transporter technology in another application, one that does not involve drug resistance, so they are optimistic. The discovery of effective arginine transporters could be the key to treating ovarian cancer, as well as other diseases that develop drug resistance, more effectively.


'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Stanford study highlights cost-effective method of lowering heart disease risks
2. Different method of evaluating the urinary tract system reduces radiation dose
3. Report on patients access to cancer drugs uses flawed methods to reached flawed conclusions
4. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
5. Researcher developing new method for hearing loss assessment
6. Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal
7. GPS-like technology helps pinpoint best methods for moving injured players
8. New Seminar Series from Activator Methods Teaches Doctors a Unique Approach to Improving Nations Chiropractic Care: Focus on the Patients
9. Less invasive lymph node biopsy method could spare thousands unnecessary operations
10. 454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It
11. Manchester researchers announce new methods of beating breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2015)... May 25, 2015 According to a ... market growth in hip external fixation market is driven ... U.S. population and advancements in infection prevention technologies. As ... fractures are currently accounting for the largest total number ... with falls and accidents. As a result, the average ...
(Date:5/25/2015)... May 25, 2015 Join Fiona's Soccer Camp ... two-hour instructional clinic. Irish National Player, Fiona O'Sullivan will ... them a taste of her coaching style. Fiona has three ... Camps in Novato are at Lynwood Elmentary School (June 15-19) ... High School - June 6th, 2015 - 1:00-3:00pm. Bring a ...
(Date:5/24/2015)... Pacific Prime has announced that they have launched the ... cost of individual international health insurance. Titled: The Cost of Health ... of health insurance in six top expat destinations, which are also ... Hong Kong , Singapore , China , ... the UK , Article 2 presents an in-depth look ...
(Date:5/24/2015)... May 24, 2015 Scientists with Cardno ... on air quality compliance issues that may have raised ... Surviving Mesothelioma has just posted an article on the ... , The group found airborne asbestos levels well above ... between 1984 and 2011. , “Asbestos compliance sampling data ...
(Date:5/24/2015)... 2015 Medicx Media Solutions ... executive Jay Krihak as its head of programmatic ... up its expertise and leadership position in the ... Health sectors. , Krihak is an experienced, award-winning ... Krihak led sales planning teams for mobile platform ...
Breaking Medicine News(10 mins):Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 2Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 3Health News:US Sports Camps and Nike Soccer Camps Offer Complimentary Instructional Clinic with Fiona's Soccer Camp 2Health News:Pacific Prime Releases 2nd Article of Cost of Health Insurance Report 2Health News:New Analysis Finds Too Many Employers Ignored OSHA Asbestos Guidelines, According to Surviving Mesothelioma 2Health News:Medicx Media Solutions Expands Executive Team 2
... News) -- Intensive control of blood sugar levels reduces ... diabetics, new research indicates. However, the evidence did ... actually developing severe kidney disease. The two signs ... conditions known as microalbuminuria and macroalbuminuria. These are characterized ...
... (May 29, 2012) Researchers from South Korea, Sweden, ... to restore neuron function to parts of the brain ... pluripotent stem cells into animal models. Induced ... human somatic cells such as skin, and can be ...
... May 29, 2012 Older adults who don,t get ... exposure may be at increased risk of developing mobility ... Baptist Medical Center. , "This is one of the first ... the onset of new mobility limitations or disability in older ...
... genetic disorders have uncovered insights into those diseases ... divide. Focusing on the cohesin complex, a group ... pairs, scientists have discovered mutations that disrupt cohesin, ... cohesinopathies. "We are learning more about how ...
... May 29, 2012 -- The discovery of a mummified ... scientific team to conduct a genetic analysis on a liver ... C2 sequence common in Southeast Asia. Additional analysis ... model to study the evolution of chronic hepatitis B and ...
... Texas For 50 years scientists have been unsure how the ... basic innate immune responses. That mystery has now been solved, thanks ... The answers may help clear the way for a ... such as V. cholerae , but instead disable their defenses ...
Cached Medicine News:Health News:Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study 2Health News:Researchers restore neuron function to brains damaged by Huntington's disease 2Health News:Older adults may need more vitamin D to prevent mobility difficulties 2Health News:Mutations impair childhood growth and development by disrupting organization of chromosome pairs 2Health News:16th-century Korean mummy provides clue to hepatitis B virus genetic code 2Health News:50-year cholera mystery solved 2
(Date:5/21/2015)... , May 21, 2015 ... has announced the addition of the ... their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The ... and size the world market for Arthroscopy ... identifies trends impacting the market for these ...
(Date:5/21/2015)... 21, 2015  (MUSE Booth # 1510)What:Automating continuous ... (EHR) is invaluable in any hospital setting, but ... a requirement and mainstream in healthcare, the integration ... EHR is gaining traction in MEDITECH facilities.During MUSE ... Site Project Manager & Clinical Analyst at McLaren ...
(Date:5/21/2015)... England , May 21, 2015 ... Bekämpfung von Arzneimittelfälschungen - Zwecks Leistungsvergleich ... Arzneimittelprüfdienstes wird auf EG-Mitgliedstaaten verwiesen, in ... betrieben werden.  Wählen Sie ein Aegate-Land: ... der Richtlinie zur Bekämpfung von Arzneimittelfälschungen ...
Breaking Medicine Technology:Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Hospital Streamlines ICU Efficiency with Timely Data Integration 2Hospital Streamlines ICU Efficiency with Timely Data Integration 3EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 2EU-Arzneimittel-Richtlinie für gefälschte Medikamente; Aegate-Zusammenfassung als reale Bewertung aus Belgien 3
... , April 29, 2010 Albireo today,announced ... recent study,assessing the safety, tolerability and efficacy of A3309 ... compound for,the treatment of irritable bowel syndrome with constipation ... during the 2010,Digestive Disease Week (DDW) annual meeting being ...
... SALT LAKE CITY , April 28 Sonic Innovations, ... Administration (VA), is conducting ongoing training events for government clinicians.  The company ... in San Diego, California and April 25 through ... for May 3 through 5 in Salt Lake City, ...
Cached Medicine Technology:Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 2Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 3Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 4Albireo Announces Positive Results From a Study With A3309 in Patients With Chronic Constipation 5Sonic Innovations Conducts National Training Events for Government Clinicians 2Sonic Innovations Conducts National Training Events for Government Clinicians 3
BD Vacutainer® Heparin Tubes are spray-coated with either lithium heparin or sodium heparin and are used for plasma determinations in chemistry....
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
Inquire...
Medicine Products: