Navigation Links
New method powerfully boosts efficiency of RNA interference (RNAi) in shutting down genes
Date:2/24/2011

As against that gene could shut down its activity efficiently. The success of their approach also means that scientists might no longer have to rely on current algorithms that are often not accurate in predicting which shRNA would work best at shutting down any given gene.

"There is still very little that is known about small RNA biogenesis," says Hannon. "But this assay has now allowed us to explore this process at a scale that wasn't feasible before." The scientists' analysis of the 20,000 small hairpin RNAs, and especially those recovered from cells in which the target gene had been efficiently shut off has revealed new insights into this process and drastically improved the recipe for creating a potent RNAi trigger. "Our assay has given us a strong framework for rational design of small hairpin RNAs," says Lowe.


'/>"/>

Contact: Hema Bashyam
bashyam@cshl.edu
516-367-6822
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Live with Regis and Kelly Reveal A REVOLUTIONARY Pain Relief Method
2. Two Surgical Methods Equally Successful for Prostate Cancer
3. Psychiatrys main method to prevent mistaken diagnoses of depression doesnt work: NYU study
4. New testing method hints at garlics cancer-fighting potential
5. MSU scientists develop more effective method of predicting lead-poisoning risk
6. Blood Draw Dilemma: New Summit Health Article Helps Employers Choose the Best Screening Method
7. Worlds most useful tree provides low-cost water purification method for developing world
8. FDA, FSIS, CDC Collaborate on Methods to Measure Success of Food Safety Programs
9. Los Angeles Hair Transplant Cosmetic Surgeon Corrects Bad Hair Transplants With New Hair Restoration Method
10. An improved method for calculating tumor growth
11. New method to grow arteries could lead to biological bypass for heart disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... September 15, 2014A prospective study that compared patient-reported ... with bone metastases demonstrates that single fraction radiation ... fraction radiation therapy (MFRT) when pain, function and ... presented today at the American Society for Radiation ... indicates that improvements in patients, pain, function and ...
(Date:9/16/2014)... Poster and Poster Discussion abstracts to be presented at ... Wednesday, 17 September 2014 at 12:00 (CEST) to give ... from the European medical oncology Congress, under the leading ... at the point where genuinely targeted therapy is now ... medicine means we are all working towards a common ...
(Date:9/16/2014)... PA (PRWEB) September 16, 2014 ... Pain Management practice by Ranking Arizona magazine, has selected ... implementation across its enterprise. , With TPC seeing ... a vast data repository that was managed through “home ... both the management and clinical leadership teams. “Our ...
(Date:9/16/2014)... Albany, New York (PRWEB) September 16, 2014 ... intelligence firm states that the global facial care market ... billion by 2019. The report, titled ‘Facial Care Market ... Facial Creams, Face Wash, Cleansing Wipes, Serums and Masks ... Industry Analysis, Size, Share, Growth, Trends and Forecast 2013 ...
(Date:9/16/2014)... Florida Hospital announced today it is teaming up with ... become the Presenting Sponsor of the 2014-15 and 2015-16 ... wellness partner. As the Presenting Sponsor for the next ... name inclusion on all Lightning advertising campaigns and materials ... a sponsorship partner of the Lightning since 2011, and ...
Breaking Medicine News(10 mins):Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 2Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 3Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 4Health News:ESMO 2014 Congress Preview 2Health News:The Pain Center of Arizona (TPC) Implements Analance™ BI for Actionable Intelligence 2Health News:The Pain Center of Arizona (TPC) Implements Analance™ BI for Actionable Intelligence 3Health News:Global Facial Care Market Will Report a CAGR of 6.9% between 2013 and 2019: Transparency Market Research 2Health News:Global Facial Care Market Will Report a CAGR of 6.9% between 2013 and 2019: Transparency Market Research 3Health News:Florida Hospital Teams up with the Tampa Bay Lightning as the New Presenting Sponsor of the 2014-15 and 2015-16 Lightning Seasons 2Health News:Florida Hospital Teams up with the Tampa Bay Lightning as the New Presenting Sponsor of the 2014-15 and 2015-16 Lightning Seasons 3
... business of recruiting,university students and new graduates is ... on this talent pool to,refresh the workforce with ... changed their university recruiting methods and programs,in decades ... a leading,pharmaceutical research firm., The study analyzes ...
... need to be aware of the connection, study says ... between diabetes and depression apparently cuts both ways: Not ... a heightened risk for developing depression, individuals with depression ... research revelation suggests that both doctors and patients need ...
... Foundation,announced the winners of its annual "Healthy Communities ... 10 at its offices in Edison, N.J.,Twelve New ... year,s,calendar and each received an iPOD shuffle., ... importance,of a healthy lifestyle and promotes awareness of ...
... Million in Savings in Past 4 Years, HARRISBURG, ... saving taxpayer funds, they should support,the Department of Public ... less for prescription drugs for children and families who ... Welfare,Estelle B. Richman said today., "Every budget season ...
... the University of Pennsylvania School of Medicine found that ... cell and developmental biology leads to an increase in ... therapies for lung-tissue repair after injury or disease. The ... of print publication in Nature Genetics . , ...
... Continues to Draw Top Research Institutes,Talent, and Corporate Labs That Are Looking ... ... Future, SAN DIEGO, June 17 /Xinhua-PRNewswire/ -- Singapore,s investment ... the fastest growing bioclusters in the world. R&D spending in the,biomedical sciences ...
Cached Medicine News:Health News:Best Practices: Achieving Excellence in Staffing and Recruiting Methods 2Health News:Diabetes and Depression Go Hand-in-Hand 2Health News:Diabetes and Depression Go Hand-in-Hand 3Health News:AMERIGROUP Foundation Announces Winners of 'Healthy Communities Art Project' 2Health News:PA Secretary of Public Welfare Urges General Assembly To Support Saving $100 Million Through Smarter Pharmacy Benefit Management 2Health News:PA Secretary of Public Welfare Urges General Assembly To Support Saving $100 Million Through Smarter Pharmacy Benefit Management 3Health News:Penn researchers find key developmental pathway activates lung stem cells 2Health News:Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research 2Health News:Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research 3Health News:Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research 4Health News:Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research 5Health News:Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research 6
(Date:9/16/2014)... BRIDGEWATER, N.J. , Sept. 16, 2014 /PRNewswire/ ... pharmaceutical company focused on developing and commercializing therapeutic ... renal and infectious diseases, announces the amendment and ... and E preferred stock and related warrants, as ... 2014 common stock and warrant financing, to remove ...
(Date:9/16/2014)... Imprimis Pharmaceuticals, Inc. (Nasdaq: IMMY ... quality and novel medicines to physicians and patients at ... Mark Baum will be a presenter at the ... New York City.  Mr. Baum will discuss the company,s ... in ophthalmology. The presentation is scheduled for 10:40 a.m. EST ...
(Date:9/16/2014)... Sept. 16, 2014  Wearable sports and activity ... less than two years, producing a massive amount ... huge opportunity exists for leveraging this data to ... ) introduced a first-of-its-kind wearable analytics platform for ... of clinical research linking activity and health risks, ...
Breaking Medicine Technology:CorMedix Amends and Restates Outstanding Securities to Remove Provisions Causing Derivative Liability Classification 2CorMedix Amends and Restates Outstanding Securities to Remove Provisions Causing Derivative Liability Classification 3Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 2Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 3Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 4Doctors Launch Initiative to Bridge Gap Between Wearables and Meaningful Health Data 2Doctors Launch Initiative to Bridge Gap Between Wearables and Meaningful Health Data 3
... Inc., a pioneer in the area of digital PCR, is ... to evaluate the capabilities of digital PCR and see the ... will start on Monday, September 12 in Boston and finish ... The QuantaLife ddPCR System claims to be the world,s most ...
... SILVER SPRING, Md., Aug. 26, 2011 The FDA ... ensuring the safety of their food and medical supplies ... week,s expected hurricane-related rain, possible flooding and power outages. ... The agency also reminds consumers that it is important ...
Cached Medicine Technology:QuantaLife™ Kicks Off Droplet Digital™ PCR Road Show 2FDA Hurricane Preparedness Checklist 2FDA Hurricane Preparedness Checklist 3FDA Hurricane Preparedness Checklist 4
... ACS allows visualization of virtually the ... essentially coaxial positioning of the lens on ... detachment surgery, repairing giant retinal tears, diagnosing ... examining the peripheral retina in a vitreous ...
... somewhat higher magnification and increased ... best suited for detailed visualization ... Central Retinal is ideal for ... membrane peeling in proliferative vitreoretinopathy ...
... MiniQuad allows visualization of virtually the ... with essentially coaxial positioning of the ... excellent for retinal detachment surgery, repairing ... anterior proliferative vitreoretinopathy and for examining ...
... Lens enhances iridectomy procedures by providing ... conventional iridectomy lens designs) with exceptional ... this lens has been increased from ... The MagPlus comes standard with LaserWindow ...
Medicine Products: