Navigation Links
New method of tissue banking makes gene analysis more practical for lung cancer
Date:7/15/2010

Analyzing the genes expressed by cancer cells allows for a better understanding of that patient's specific disease and in turn, a more personalized approach to treatment. But obtaining the RNA from a tumor in the lungs in order to conduct the genetic analysis is a challenging prospect. Currently, lung cancer researchers are limited to using RNA extracted from early-stage tumors removed during surgery. The small quantities of tissue extracted during routine diagnostic biopsies have not been useful to researchers, due to their small size and the variety of ways they have been processed.

Since oftentimes surgery is not an option in advanced lung cancer, genetic analysis of the tumor is critical, there is a need to obtain good quality RNA samples from tumor tissue taken via biopsy, no matter how the biopsy procedure is conducted.

In a study in the July edition of the Journal of Thoracic Oncology, Malcolm H. Lawson describes a process to successfully obtain and to store high quality RNA from lung tumor biopsies. Lawson and fellow researchers at the Cancer Research UK Cambridge Research Institute and Papworth Hospital, both in the United Kingdom, received consent from patients to take extra biopsies for research purposes during the diagnostic procedure. Biopsies were obtained using the three most frequently used techniques -- endobronchial biopsy forceps, transbronchial needle aspirate - or CT-guided needle biopsy. Acceptable RNA for gene expression analysis was extracted from 72 percent of lung cancer biopsies.

Lawson and team immediately froze some of the biopsies in liquid nitrogen, while the others were first treated with an RNA preservative (RNAlater) before freezing. Use of the RNA preservative resulted in higher quality, more intact RNA from biopsies taken via all methods.

Storage in the RNA preservative doubled the number of biopsies that met the minimum yield and quality criteria for analysis compared with immediat
'/>"/>

Contact: Megan Richter
mrichter@spectrumscience.com
202-587-2556
International Association for the Study of Lung Cancer
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. New UC Davis study finds early Alzheimers identification method
2. Principal Protected Index Investing Provides Innovative Method to Significantly Reduce Stock Market Loss and Risk
3. New Method Proposed for Gauging Hospital Infection Rates
4. Delivery Method May Determine the Bacteria Babies Acquire
5. Violence, not overdose, the likely method of suicide in veterans with substance use disorders
6. Gene-Based Detection Method Might Spot HIV Earlier
7. New method manipulates particles for sensors, crime scene testing
8. New treatment method safe, effective for advanced melanoma patients
9. Color-coded tracking method helps scientists analyze outcomes of newly transplanted tissue
10. OHM Cheers End of the "Build it Bigger" Directive: Metropolitan Communities Look to New Methods to Evaluate, Rehabilitate Aging Sewer Systems
11. PMSI Advocacy Efforts Prompt CMS to Improve MSA Review Methodology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... UK (PRWEB) May 24, 2013 The leading ... 50% discount offer on short prom dresses . Now ... quality that is standard with the brand name since its ... collections in prom dresses. And now this huge discount offer ... , “I feel highly privileged to announce that ...
(Date:5/23/2013)... 2013 Sublime Beauty® is introducing ... line, with a 35% discount through May ... two proprietary products, the Cellulite Whisperer® Gel ... Purchasers receive a report "Getting Control of Your ... a wonderful grapefruit scent," says Kathy Heshelow, founder ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Whether working ... Operations Forces and law enforcement need an added layer ... Security Enhancer, Night VISER , is an effective ... motion sensing system to increase border and perimeter security. ... VISER have more than tripled over the past three ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Orange County film ... release of ProLeak, light leaks for Apple's Final Cut ... for FCPX , you no longer have to worry about ... movement in your shot," Said Christina Austin, CEO of Pixel ... while maintaining a natural look." , ProLeak from Pixel Film ...
(Date:5/23/2013)... If you are one of the estimated ... the food spread this Memorial Day weekend could put ... dogs and ice cream have become cornerstones of the ... sufferers often feel the painful effects of consuming these ... Lourdes Medical Associates. , IBS occurs when the large ...
Breaking Medicine News(10 mins):Health News:short prom dresses Offers Abnormally Low Discount on Its New Collections 2Health News:Fresh Organics in the New Cellulite Whisperer® Products from Sublime Beauty®; "Get Ready for Summer Sale" Continues 2Health News:Lighting Up the Night: ARA Announces Record Sales of Its Night VISER System 2Health News:Lighting Up the Night: ARA Announces Record Sales of Its Night VISER System 3Health News:Pixel Film Studios Releases ProLeak Light Leaks for Final Cut Pro X Today 2Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 2Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 3
... ... his roots after service in the military and opens a state-of-the-art aesthetic enhancement practice. ... (Vocus) September 15, 2009 -- ... at Bethesda Naval Medical Center outside Washington, DC, a native Chicagoan has come home. Dr. ...
... ... Things Kids Can Do empowers kids to work on fixing areas ... industry experts. Each book in the series tackles a different subject such ... of 32 Experts in each industry to reinforce the positive messages. Health ...
... ... into a joint venture agreement with China-based Asia Air Medical (AAM) in which the two ... and Taiwan) to expand air medical transport operations. , ... Birmingham, AL (PRWEB) September 15, 2009 -- AirMed Asia, a subsidiary ...
... , , EL SEGUNDO, Calif., ... ), the only national organization creating hope in a comprehensive ... cure is mourning the loss of legendary actor Patrick Swayze. His ... subsequent battle put a spotlight on pancreatic cancer, the fourth leading ...
... Sept. 14 Particle beam radiation therapy, a technology used ... clinicians to be better than traditional radiation, but there is ... radiation therapy, according to a new comparative effectiveness report funded ... , , "As technologies develop and new ...
... , , , ... illness plan from Colonial Life & Accident Insurance Company can help many ... problems. Even with good health insurance, a serious illness, such as a ... expenses. , , "Even employees who plan for ...
Cached Medicine News:Health News:Native Chicago Plastic Surgeon Opens New Cosmetic Surgery Practice 2Health News:Native Chicago Plastic Surgeon Opens New Cosmetic Surgery Practice 3Health News:Innovative New Book Series Encourages Kids to Go Behind Their Parents' Backs and Listen to Experts on Important Health and Wellness, Education, Personal Finance and Nutrition 2Health News:Innovative New Book Series Encourages Kids to Go Behind Their Parents' Backs and Listen to Experts on Important Health and Wellness, Education, Personal Finance and Nutrition 3Health News:Innovative New Book Series Encourages Kids to Go Behind Their Parents' Backs and Listen to Experts on Important Health and Wellness, Education, Personal Finance and Nutrition 4Health News:Innovative New Book Series Encourages Kids to Go Behind Their Parents' Backs and Listen to Experts on Important Health and Wellness, Education, Personal Finance and Nutrition 5Health News:AirMed Asia has Entered into a Joint Venture Agreement with Asia Air Medical to Expand Air Medical Transport in China 2Health News:The Pancreatic Cancer Action Network Is Saddened by the Death of Actor Patrick Swayze 2Health News:Particle Beam Radiation Therapy Promising But Unproven for Treating Cancer 2Health News:Particle Beam Radiation Therapy Promising But Unproven for Treating Cancer 3Health News:Critical Illness Plans Help Pay for What Health Insurance Won't 2Health News:Critical Illness Plans Help Pay for What Health Insurance Won't 3
(Date:5/23/2013)... May 23, 2013  MGC Diagnostics Corporation (NASDAQ: ... technology company, today scheduled a conference call to discuss ... year 2013, ended April 30, 2013. The call will ... 2013. The Company will report financial results for the ... close on Thursday, May 30, 2013. ...
(Date:5/23/2013)... 23, 2013 More than half of women ... from chemotherapy and still have excellent outcomes. To educate ... of the largest sources of online consumer information about ... Facebook page provide recently diagnosed women with information sources, ... chemotherapy. "We anticipate these innovative social media ...
(Date:5/23/2013)... May 23, 2013  Texas, premier physician associations today ... the survival tools they need to provide demonstrably better ... health care marketplace. "I am confident the ... practices," said Stephen L. Brotherton , ... Texas doctors are determined to make ...
Breaking Medicine Technology:MGC Diagnostics Corporation to Report Second Quarter Fiscal 2013 Financial Results on Thursday, May 30, 2013 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4
For the quantitative in vitro determination of lithium in serum and plasma. Wavelength: 550 nm. Linear range: up to 4 mm....
... Genegnome HR is a new dedicated high ... Genegnome completely automates the process of imaging ... and is extremely easy to use, thanks ... powerful imaging hardware. Based on the standard ...
... range of Platelet aggregometers allows to ... particular needs. Single, dual and four ... recorder outputs or digital computer outputs. ... aggregometers, which measure platelet aggregation in ...
... The PAP-4CD is a four channel platelet ... data system. Operating in conjunction with Microsoft ... color display of tests, automatic storage of ... data management. Four test modes are available: ...
Medicine Products: