Navigation Links
New method identifies rat poison in humans
Date:5/27/2008

Researchers at the Norwegian Institute of Public Health (NIPH) have developed a method to identify bromadiolone poisoning in humans. Bromadiolone is a rat poison that can be purchased freely in shops. A number of cases have been reported internationally where people have been poisoned, with a mortality rate of 20 percent.

Blood-thinning substances have been used for many years as rodenticides. Warfarin was previously used but due to resistance development, the so-called super-warfarins were introduced. These substances are 100 times as potent as warfarin.

A commonly used super-warfarin is bromadiolone (sold as the brand name Temus in Norway). Few laboratories have been able to prove the presence of bromadiolone in human samples and little is known what happens to the substance in the human body.

Now researchers at the NIPH have developed an analysis method to spot the presence of bromadiolone. The cause of serious bleeding disturbances in a female patient was investigated during a recent poisoning case. It appeared that the woman had been exposed to blood-thinning substances. Blood samples uncovered that she had been repeatedly exposed to bromadiolone.

The researchers discovered that bromadiolone is present in blood for a much shorter time than expected. The concentration of bromadiolone is higher in blood plasma than in whole blood, which is important to note when samples in different media are interpreted. After storage of the blood samples in the freezer at -20 degrees Celsius, followed by thawing for reanalysis, the concentration of bromadiolone fell over time.

In order to treat bleeding disorders, the cause of the patients condition must be identified as soon as possible. When poisoning with blood-thinning substances is suspected, an analysis method that can identify the superwarfarin bromadiolone, plus other superwarfarins and blood-thinning substances, is now available.


'/>"/>

Contact: Media Contact
info@fhi.no
Norwegian Institute of Public Health
Source:Eurekalert

Page: 1

Related medicine news :

1. Local Methodists Host West African Choir, South African Leader at Historic Conference
2. Population Health Impact Institute Releases Methods Evaluation Process(TM) (MEP(TM)) Accreditation Standards for Public Comment Period
3. Invasive methods unnecessary for prostate cancer radiation therapy treatment planning
4. Population Health Impact Institute to Host First Methods Evaluation Process(TM) (MEP(TM)) Workshop at Annual CMSA Conference
5. New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer
6. New method proposed for determining which patients should get treatment for colorectal cancer
7. Kresge Foundation Employs New Funding Methods in its First Quarter Grant Awards of Nearly $43 Million
8. Air Methods Corporation Confirms Fatal Accident in Wisconsin
9. Air Methods Reports 1Q2008 Results and 2Q2008 Update
10. Integrium Introduces Its Integrium Clinical Excellence (ICE) Methodology to Assure Consistent Delivery of Sponsor Clinical Trials
11. New OPAL Therapy presents simple, cost-effective method of treating HIV infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... Youth substance abuse is a serious problem ... Houston, TX. Substance abuse can happen to people of ... alcohol dependency in higher numbers than ever before. ... but don’t know where to find professional youth rehab. ... challenge because most treatment options are designed for adults. ...
(Date:8/23/2014)... Summer vacation is almost over and before we know ... shopping for school supplies and a new wardrobe might take ... students to also spend some time brushing up on bed ... thrive in heavily populated places,” said Randy Rupert, Bed Bug ... perfect settings for bed bugs to take up residence.” , ...
(Date:8/22/2014)... 23, 2014 2014 Deep Research ... professional and in-depth research report on the Glucose ... information, including Glucose Meter definition, classification, application, and ... This research covers the international market analysis, including ... covering macroeconomic environment & economic situation analysis. The ...
(Date:8/22/2014)... Today, Zane Benefits, the #1 Online Health ... Plans. , According to Zane Benefits, employers are adopting ... the cost of healthcare without reducing coverage for employees. ... can be confusing. , The new guide contains a ... types of ABHPs. It also explains the similarities, ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 MyWriters.com ... is written by marketing experts for marketers to help ... has caught the attention of Shane Michaels, prompting an ... Internet marketing in any way knows that content is ... the industry,” reports Michaels. “But even though content is ...
Breaking Medicine News(10 mins):Health News:New Houston Hotline Assisting Juveniles in Locating Dependable Rehabilitation Help 2Health News:Expert Advice for a Bed Bug-Free School Year 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 3Health News:My Writers: Review Exposes Online Source for Quality Marketing Content 2
... the Dec. 15 issue of the Journal ... associations exist between parent-reported insomnia symptoms and medical ... school-aged children. Results of multivariate regression ... more likely in children with gastrointestinal regurgitation and ...
... ... and NaturalFill™ revolutionary new liposuction and fat transfer treatments can help people slim down, ... ... -- The combination of AQUALIPO™ and NaturalFill™ can remove excess fat from the abdomen ...
... , BRAINTREE, Mass., Dec. 14 Haemonetics Corporation (NYSE: ... new legal action to stop Fenwal Inc.,s continued patent infringement ... a modified separation chamber. Fenwal allegedly modified its separation ... the Court prohibiting Fenwal,s continued sale of infringing products after ...
... , MONDAY, Dec. 14 (HealthDay News) -- U.S. researchers have ... to heart failure. , The team at Washington University School ... large group of white patients with heart failure, and identified ... heart failure. Further analysis of 1,117 whites with heart failure ...
... , , COLUMBUS, ... making major changes in operations and services in order to deal ... (franchise permit fee) from $6.25 to $12.01 per bed per day, ... facility will pay an additional $17,520 to the state each month, ...
... Dec. 14 On December 9, 2009, the United States Court ... insurance companies are "plans" and therefore subject to federal jurisdiction. (US ... issued by insurance companies may be subject to federal jurisdiction under ... first case an insurance company itself has been held to be ...
Cached Medicine News:Health News:Insomnia symptoms linked with medical complaints in young school-aged children 2Health News:Insomnia symptoms linked with medical complaints in young school-aged children 3Health News: Free Webinar Series at Aqualipo.com Shows How New Combination Liposuction/Fat Transfer Treatment Helps Patients Slim Down and Reduce Facial Wrinkling 2Health News: Free Webinar Series at Aqualipo.com Shows How New Combination Liposuction/Fat Transfer Treatment Helps Patients Slim Down and Reduce Facial Wrinkling 3Health News:Haemonetics Files a New Legal Action to Stop Fenwal Inc.'s Continued Patent Infringement 2Health News:Haemonetics Files a New Legal Action to Stop Fenwal Inc.'s Continued Patent Infringement 3Health News:Survey Shows Tax Increase Forcing Ohio Skilled Nursing Facilities to Make Cuts 2Health News:Survey Shows Tax Increase Forcing Ohio Skilled Nursing Facilities to Make Cuts 3Health News:Insurance Now Subject to Federal Jurisdiction 2
(Date:8/21/2014)... 21, 2014  Aptuit LLC announces that Aptuit ... , has enhanced its capabilities in the ... and large molecules, including biologic drugs, metabolites, and ... Q-TOF mass spectrometer. In making the ... said, "The expanded large molecule capability enhances our ...
(Date:8/21/2014)... LOS ANGELES , Aug. 21, 2014 The ... areas of the human body. Signals carried to and from ... our motor skills and nervous system. Injury or ailment here ... pain, or with a loss of control over their body. ... impact on a person,s life, there are more options available ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- Inc. magazine today ... third straight year, No. 349 in Health on ... of the nation,s fastest-growing private companies. The list ... important segment of the economy—America,s independent entrepreneurs. Companies ... LinkedIn, Zillow, and many other well-known names gained ...
Breaking Medicine Technology:Aptuit SSCI Adds Ultra High Resolution Q-TOF Mass Spectrometer for Large & Small Molecule Analyses 2Don't Live in Pain: Four Life Improving Benefits of Back Surgery 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: