Navigation Links
New method assesses risks for heart failure patients

COLUMBUS, Ohio Data from 260 hospitals across the United States has led to the creation of a new method for physicians to more accurately determine the severity of heart failure in patients upon hospital admission, with a goal of reducing in-hospital mortality and more quickly identifying triage methods and treatment decisions. The model is discussed in the July 29 issue of the Journal of the American College of Cardiology.

"Heart failure patients experience high rates of hospital stays and poor outcomes," said Dr. William Abraham, director of cardiovascular medicine at Ohio State University Medical Center and primary author of the article. "By utilizing this model, we can more quickly identify patients at risk for in-hospital mortality who might benefit from more aggressive monitoring and intervention."

The model was developed as part of the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) study, which offered recommendations to improve treatment of congestive heart failure based on monitoring more than 48,000 patients.

Baseline information, treatment patterns and in-hospital outcomes were recorded for each patient upon admission. A model was then developed to identify significant predictors of in-hospital mortality, such as gender, medical history, vital signs at admittance, heart failure characteristics or history, laboratory data and admission medication.

Of the more than 48,000 patients admitted for heart failure, the in-hospital mortality rate was approximately four percent, providing an adequate number of events to evaluate predictors.

The patient characteristics most predictive of in-hospital mortality were admission creatinine levels, systolic blood pressure and patient age. Increased risk was also associated with conditions such as liver disease, past cerebrovascular issues, vascular disease and chronic obstructive pulmonary disease. Diabetes, gender and coronary artery disease were not significant predictors of mortality.

According to Abraham, while the model provides a reliable tool for clinicians, it reports in-hospital mortality only, and was not validated for post discharge outcomes. In addition, the mortality risk might have been influenced by other factors that were not measured, documented or included in the database. Therefore, the model can only be applied for patients in whom the variables were assessed.

"Despite numerous advances in the treatment of chronic heart failure, more work is needed to reduce the high risk of mortality for patients hospitalized for heart failure," said Abraham. "An essential next step is to study whether applying this risk prediction score will favorably impact patient care and clinical outcomes."


Contact: Doug Flowers
Ohio State University Medical Center

Related medicine news :

1. Stanford study highlights cost-effective method of lowering heart disease risks
2. Different method of evaluating the urinary tract system reduces radiation dose
3. Report on patients access to cancer drugs uses flawed methods to reached flawed conclusions
4. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
5. Researcher developing new method for hearing loss assessment
6. Medicare Prescription Drug Benefit, Nonprofit Hospitals, Ambulatory Surgery Centers, Statistical Methods, and Pay-For-Performance Highlighted In the Latest INQUIRY Journal
7. GPS-like technology helps pinpoint best methods for moving injured players
8. New Seminar Series from Activator Methods Teaches Doctors a Unique Approach to Improving Nations Chiropractic Care: Focus on the Patients
9. Less invasive lymph node biopsy method could spare thousands unnecessary operations
10. 454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It
11. Manchester researchers announce new methods of beating breast cancer
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in the traditional ... models of traditional and far-infrared saunas. , For traditional saunas, Finnleo is ... traditional Finnish sauna wood, and Finnleo uses only European Grade A Nordic White Spruce ...
(Date:11/25/2015)... ... 26, 2015 , ... Ministers, senior government and UN agencies, ... Centres of Excellence, and public R&D institutions, civil societies and other partners gathered ... 5th African Network for Drugs and Diagnostics Innovation, ANDI, Stakeholders Meeting. The three- ...
(Date:11/25/2015)... ... November 25, 2015 , ... Lakeview Health, a Jacksonville-based drug ... their sobriety and show through pictures what a positive difference it makes. The ... with the hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. Short ...
(Date:11/25/2015)... ... November 25, 2015 , ... The McHenry County law firm of ... decision obtained by Attorneys Francisco J. Botto and Alex C. Wimmer. Attorneys Botto and ... Comm’n, 2015 IL App (2d) 130884WC. , According to court documents, Adcock testified that ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... Beddit® has ... Beddit Classic sleep tracking systems. The new app features a more intuitive SleepScore™ that ... understand how well you slept. The SleepScore is created by a proprietary algorithm. Beddit ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... 25, 2015 Allergan plc (NYSE: ... Rugen Therapeutics, a start-up  biotechnology company focused on ... disorders and funded by the F-Prime Biomedical Research ... into an exclusive collaboration to support the discovery ... Disorders (ASD) and Obsessive Compulsive disorders (OCD). ...
(Date:11/25/2015)... 2015 USP 800 applies to all ... pharmacists, pharmacy technicians, nurses, physicians, physician assistants, home ... also covers all entities which store, prepare, transport, ... healthcare institutions, patient treatment clinics, physicians, practice facilities, ... --> What is the purpose of ...
(Date:11/25/2015)... 2015 Asia -based ... BioLight and the New Investors will make a direct ... a private placement. The financing will help IOPtima to ... used in the treatment of glaucoma, as well as ... IOPtimate™ system with the U.S. Food and Drug Administration, ...
Breaking Medicine Technology: