Navigation Links
New medication brings hope of jet lag cure

A team of researchers from Monash University, The Brigham and Women's Hospital (Boston), Harvard Medical School and Vanda Pharmaceuticals has found a new drug with the potential to alleviate jet lag and sleep disorders caused by shift work.

Dr Shantha Rajaratnam from Monash University's School of Psychology, Psychiatry and Psychological Medicine said tasimelteon, a drug which acts on melatonin receptors in the brain, could be a highly effective treatment for circadian rhythm sleep disorders.

The research was released today in respected publication, The Lancet.

"Our studies show that tasimelteon is able to effectively shift the rhythm of melatonin levels in the body, which are a well-established marker of the human biological clock," Dr Rajaratnam said.

"This drug has the potential to improve the quality and quantity of sleep for patients with transient insomnia caused by jet lag.

"Tasimelteon improved a patient's ability to fall asleep and then stay asleep when bedtime was shifted earlier by five hours.

"This is the equivalent of travelling eastwards and putting your clock back five hours, such as returning from India to Melbourne, or Dubai to Perth.

"About two thirds of all international travellers who cross time zones experience jet lag symptoms, which include disruption of sleep, difficulty getting to and staying asleep, sleepiness during waking hours and gastrointestinal symptoms."

He said the drug could also help those who work at night or early in the morning.

"An estimated one in five work outside the regular nine-to-five pattern. In the United states alone it is estimated 19.7 million people start work between 2.30 and 7 am," Dr Rajaratnam said.

"Our work has shown the drug to be highly potent, having the strongest effect when first taken; a single dose treatment was found to be effective for this type of sleep disturbance."

The drug is in the later stages of trials and must undergo rigorous testing before being made available to consumers.


Contact: Shaunnagh O'Loughlin
Monash University

Related medicine news :

1. UHC and Safecor Health Announce Multi-Year Agreement for Repackaging Bar-Coded Medications
2. Pharmacy OneSource Launches SPEAK Initiative to Promote Medication Safety Awareness
3. Welvista Announces Partnering with sanofi-aventis U.S. to Provide Medication at No Cost to the Uninsured
4. Study: Patient Harm More Common with Patient-Controlled Pain Medication
5. Disclosure of medication can save a patients life
6. Cephalon and ImmuPharma Sign a $15 million Option Agreement for Late- Stage Experimental Lupus Medication
7. Unveils the Next Generation Medication Safety Tool to Help Consumers Avoid Dangerous Drug Interactions
8. ADHD Medications Dont Pose Cancer Risk
9. New Jersey Jury Awards $12.9 Million to Three Patients Whose Use of Roche Acne Medication Accutane Found to Cause Severe Bowel Illness
10. Publishes Safe Strategies for Drug Savings to Help All Americans Get Affordable Medication
11. New study: A Common Class of GI Medications Reduce Protection Against Heart Attack in Patients Taking Widely Prescribed Cardiovascular Drug
Post Your Comments:
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... Sept. 27, 2017  Commended for their devotion to personalized ... Ranked as number one in the South Florida Business Journal,s ... Inc. 5000 yearly list, the national specialty pharmacy has found ... Bardisa will soon be honored by SFBJ as the ... Set to receive his award in October, Bardisa ...
(Date:9/25/2017)... 25, 2017   Montrium , an industry ... today—from the IQPC Trial Master Files & Inspection ... that EastHORN Clinical Services has selected eTMF ... TMF management. EastHORN, a leading European contract research ... increase transparency to enable greater collaboration with sponsors, ...
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, Inc. ... response letter from the U.S. Food and Drug Administration ... of sirukumab for the treatment of moderately to severely ... additional clinical data are needed to further evaluate the ... severely active RA. ...
Breaking Medicine Technology: