Navigation Links
New materials with potential biomedical applications

Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates were discovered, as their ability to form physical gels in pure water was reported for the first time in a recent study performed in collaboration with the Universities of Jyvskyl and Eastern Finland.

The gelation tendencies of four bisphosphonates were studied in detail under the baton of Academy Research Fellow Elina Sievnen and her group at Department of Chemistry of University of Jyvskyl. Moreover, the structures of the formed gels were investigated in detail by a wide selection of methods. Docent Manu Lahtinen from Department of Chemistry of University of Jyvskyl contributed significantly in the structural analysis part of the study. The examined bisphosphonates were designed and prepared under the supervision of Professor Jouko Vepslinen at the School of Pharmacy of the University of Eastern Finland (Kuopio Campus). The study is part of the doctoral thesis of postgraduate student Aino Alanne from the School of Pharmacy of the University of Eastern Finland.

The current study increases our understanding of the factors affecting on processes leading to gelation and may provide new materials for innovative applications in biomedicine. This kind of materials could, for example, serve as substitutes to restore, maintain, and/or improve the function of bone tissue. Moreover, they might act as scaffolds to mimic the extracellular matrix and provide support for cell adhesion, migration, and proliferation.

The study was published in the prestigious international Journal of Materials Chemistry B: Materials for biology and medicine, and the article was featured in the cover art of issue 45 (2013).

Supramolecular gels are responsive and reversible

Physical, also known as supramolecular, gels form when low molecular mass compounds interact with one another by forming a network, which finally adsorbs the solvent into its structure. Supramolecular gels differ from the traditional chemical (polymeric) gels as being reversible. They can be subjected to a stimulus, e.g. heating, to which they respond by changing forms. After the exposure ceases, the gel is re-formed.

Supramolecular gels have several applications in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.


Contact: Jouko Vepsäläinen
University of Eastern Finland

Related medicine news :

1. No Added Cancer Risk From Hip Replacement Materials: Study
2. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
3. A TECNALIA study reveals the loss of nanomaterials in surface treatments caused by water
4. Aldrich Materials Science discovers liquid-free preparation of metal organic frameworks
5. Contemporary Product Solutions Released their Winter Dental Magazine by Evaluating Dental Products and Dental Materials From a "Total Team" Perspective
6. SFU materials and particle science attract government funding
7. Huntsman Advanced Materials Launches Commercial Acceleration Program with SpecialChem to Support Epoxy Specialty Components Business
8. Spiritual Life Coaching School Holistic Learning Center Releases Official Client Materials
9. UTSA engineering dean C. Mauli Agrawal receives award from Society for Biomaterials
10. Launch of Chinese-German Center for Bio-Inspired Materials at Mainz University Medical Center
11. New Evaluation of the Heart Truth® Professional Education Materials Released
Post Your Comments:
(Date:11/26/2015)... ... 2015 , ... Somu Sivaramakrishnan announced today that he joined ... offers travelers, value and care based Travel Services, including exclusive pricing on a ... cabin upgrades and special amenities such as, shore excursions, discounted fares, travel gifts ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... of retro-fused, self-animating trailer titles with ProTrailer: Vintage. This newly styled ProTrailer pack ... trailer titles work with any font, giving users limitless opportunities to stylize and ...
(Date:11/25/2015)... ... November 25, 2015 , ... The holiday season ... and pleasing the palates of attendees is of the utmost importance. Whether you ... seasonal get-together, give these recipes a try this holiday season. , Turkey Croquettes ...
(Date:11/25/2015)... ... November 26, 2015 , ... ... (AUC), European Union (EU), ANDI Pan African Centres of Excellence, and public R&D ... Nairobi (UNON) for the opening of the 5th African Network for Drugs and ...
(Date:11/25/2015)... Cleveland, OH (PRWEB) , ... November 25, 2015 , ... ... dental implants in Cleveland, OH , are invited to attend Dr. Mark Iacobelli’s Advanced ... 5th this year in Cleveland, OH. , As the co-founders of Advanced Implant ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... -- Research and Markets ( ) has ... Horizons and Growth Strategies in the Italian Therapeutic ... Forecasts, Competitive Intelligence, Emerging Opportunities" report to ... --> This new 247-page report provides ... monitoring market, including emerging tests, technologies, instrumentation, sales ...
(Date:11/25/2015)... 25, 2015  Amgen (NASDAQ: AMGN ) today ... with the United States (U.S.) ... biosimilar candidate to Humira ® (adalimumab). Amgen believes ... to the FDA and represents Amgen,s first BLA submission ... Harper , M.D., executive vice president of Research and ...
(Date:11/25/2015)... MINNEAPOLIS , Nov. 25, 2015  ARKRAY ... care products, continues to provide evidence demonstrating the accuracy ... the World Congress on Insulin Resistance, Diabetes and Cardiovascular ... showed that both the Company,s GLUCOCARD ® 01 ... met high accuracy requirements. The ability to accurately measure ...
Breaking Medicine Technology: