Navigation Links
New materials with potential biomedical applications
Date:11/21/2013

Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates were discovered, as their ability to form physical gels in pure water was reported for the first time in a recent study performed in collaboration with the Universities of Jyvskyl and Eastern Finland.

The gelation tendencies of four bisphosphonates were studied in detail under the baton of Academy Research Fellow Elina Sievnen and her group at Department of Chemistry of University of Jyvskyl. Moreover, the structures of the formed gels were investigated in detail by a wide selection of methods. Docent Manu Lahtinen from Department of Chemistry of University of Jyvskyl contributed significantly in the structural analysis part of the study. The examined bisphosphonates were designed and prepared under the supervision of Professor Jouko Vepslinen at the School of Pharmacy of the University of Eastern Finland (Kuopio Campus). The study is part of the doctoral thesis of postgraduate student Aino Alanne from the School of Pharmacy of the University of Eastern Finland.

The current study increases our understanding of the factors affecting on processes leading to gelation and may provide new materials for innovative applications in biomedicine. This kind of materials could, for example, serve as substitutes to restore, maintain, and/or improve the function of bone tissue. Moreover, they might act as scaffolds to mimic the extracellular matrix and provide support for cell adhesion, migration, and proliferation.

The study was published in the prestigious international Journal of Materials Chemistry B: Materials for biology and medicine, and the article was featured in the cover art of issue 45 (2013).

Supramolecular gels are responsive and reversible

Physical, also known as supramolecular, gels form when low molecular mass compounds interact with one another by forming a network, which finally adsorbs the solvent into its structure. Supramolecular gels differ from the traditional chemical (polymeric) gels as being reversible. They can be subjected to a stimulus, e.g. heating, to which they respond by changing forms. After the exposure ceases, the gel is re-formed.

Supramolecular gels have several applications in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.


'/>"/>

Contact: Jouko Vepsäläinen
jouko.vepsalainen@uef.fi
358-403-553-256
University of Eastern Finland
Source:Eurekalert

Related medicine news :

1. No Added Cancer Risk From Hip Replacement Materials: Study
2. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
3. A TECNALIA study reveals the loss of nanomaterials in surface treatments caused by water
4. Aldrich Materials Science discovers liquid-free preparation of metal organic frameworks
5. Contemporary Product Solutions Released their Winter Dental Magazine by Evaluating Dental Products and Dental Materials From a "Total Team" Perspective
6. SFU materials and particle science attract government funding
7. Huntsman Advanced Materials Launches Commercial Acceleration Program with SpecialChem to Support Epoxy Specialty Components Business
8. Spiritual Life Coaching School Holistic Learning Center Releases Official Client Materials
9. UTSA engineering dean C. Mauli Agrawal receives award from Society for Biomaterials
10. Launch of Chinese-German Center for Bio-Inspired Materials at Mainz University Medical Center
11. New Evaluation of the Heart Truth® Professional Education Materials Released
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... , ... February 05, 2016 , ... The event is ... Day Block Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund nearly $100,000 ... owner of Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect of this ...
(Date:2/5/2016)... ... 05, 2016 , ... Freed-Hardeman University President Joe A. Wiley ... joint enrollment and degree completion agreement. The agreement, which begins with the ... FHU|Dickson. , The agreement allows students to be jointly admitted to both ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... franchises from across the country gathered at the La Valencia Hotel in San ... PROSHRED Chicago was named the year’s most outstanding franchise, walking away with ...
(Date:2/5/2016)... ... ... Boar’s Head Brand®, one of the nation’s leading providers of premium delicatessen ... stress out of your party preparation – follow these easy, yet delicious recipes with ... game. , “The key to hosting a successful game-day party is creating a flavorful ...
(Date:2/5/2016)... ... ... Stuart Bentkover, MD, FACS is thrilled to announce the arrival ... tattoo removal today, Dr. Bentkover is the only doctor in Central Massachusetts to offer ... been approved by the Food and Drug Administration (FDA) as a safe and efficient ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016 Dehaier Medical ... or the "Company"), which develops, markets and sells ... China and international markets, ... which aims to concentrate the Company,s resources to ... respiratory business and to focus more on its ...
(Date:2/5/2016)... Site Profile: --> Site ... People, announced their latest primary healthcare case study where speech recognition ... and to save the practice money. Site Profile: ... Challenge: --> ,- Wirral CCG ,- VoicePower client since ... Wirral CCG ,- VoicePower client since 2013 Challenge: ...
(Date:2/4/2016)... Feb. 4, 2016  Edwards Lifesciences Corporation (NYSE: ... structural heart disease and critical care monitoring, announced today ... (ASR) agreement with Morgan Stanley & Co. LLC to ... is part of the Company,s previously authorized program to ... stock.  --> --> ...
Breaking Medicine Technology: