Navigation Links
New materials with potential biomedical applications
Date:11/21/2013

Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates were discovered, as their ability to form physical gels in pure water was reported for the first time in a recent study performed in collaboration with the Universities of Jyvskyl and Eastern Finland.

The gelation tendencies of four bisphosphonates were studied in detail under the baton of Academy Research Fellow Elina Sievnen and her group at Department of Chemistry of University of Jyvskyl. Moreover, the structures of the formed gels were investigated in detail by a wide selection of methods. Docent Manu Lahtinen from Department of Chemistry of University of Jyvskyl contributed significantly in the structural analysis part of the study. The examined bisphosphonates were designed and prepared under the supervision of Professor Jouko Vepslinen at the School of Pharmacy of the University of Eastern Finland (Kuopio Campus). The study is part of the doctoral thesis of postgraduate student Aino Alanne from the School of Pharmacy of the University of Eastern Finland.

The current study increases our understanding of the factors affecting on processes leading to gelation and may provide new materials for innovative applications in biomedicine. This kind of materials could, for example, serve as substitutes to restore, maintain, and/or improve the function of bone tissue. Moreover, they might act as scaffolds to mimic the extracellular matrix and provide support for cell adhesion, migration, and proliferation.

The study was published in the prestigious international Journal of Materials Chemistry B: Materials for biology and medicine, and the article was featured in the cover art of issue 45 (2013).

Supramolecular gels are responsive and reversible

Physical, also known as supramolecular, gels form when low molecular mass compounds interact with one another by forming a network, which finally adsorbs the solvent into its structure. Supramolecular gels differ from the traditional chemical (polymeric) gels as being reversible. They can be subjected to a stimulus, e.g. heating, to which they respond by changing forms. After the exposure ceases, the gel is re-formed.

Supramolecular gels have several applications in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.


'/>"/>

Contact: Jouko Vepsäläinen
jouko.vepsalainen@uef.fi
358-403-553-256
University of Eastern Finland
Source:Eurekalert

Related medicine news :

1. No Added Cancer Risk From Hip Replacement Materials: Study
2. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
3. A TECNALIA study reveals the loss of nanomaterials in surface treatments caused by water
4. Aldrich Materials Science discovers liquid-free preparation of metal organic frameworks
5. Contemporary Product Solutions Released their Winter Dental Magazine by Evaluating Dental Products and Dental Materials From a "Total Team" Perspective
6. SFU materials and particle science attract government funding
7. Huntsman Advanced Materials Launches Commercial Acceleration Program with SpecialChem to Support Epoxy Specialty Components Business
8. Spiritual Life Coaching School Holistic Learning Center Releases Official Client Materials
9. UTSA engineering dean C. Mauli Agrawal receives award from Society for Biomaterials
10. Launch of Chinese-German Center for Bio-Inspired Materials at Mainz University Medical Center
11. New Evaluation of the Heart Truth® Professional Education Materials Released
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2019)... ... July 10, 2019 , ... Women's Excellence is excited to offer laser vaginal rejuvenation. Laser ... such as , painful sex , vaginal dryness ... , urinary urgency , vaginal pH imbalances , recurrent ...
(Date:7/9/2019)... ... July 09, 2019 , ... A2LA is pleased to announce the accreditation ... oils, and solids. GEL Laboratories is based in Charleston, South Carolina, and is the ... first laboratory in the field of environmental testing to expand their scope to include ...
(Date:7/9/2019)... Ohio and MT. PROSPECT, Ill. (PRWEB) , ... ... ... of patient flow, staff workflow, and asset tracking technology, today announced a validated ... call platform. , Midmark RTLS has been enhancing Rauland’s nurse call platform with ...
(Date:7/9/2019)... ... July 09, 2019 , ... ... it is expanding to the Canadian marketplace through a new strategic partnership with ... pig health and production management technology to Canada’s swine industry. The partnership is ...
(Date:7/9/2019)... ... July 08, 2019 , ... East Valley Implant and Periodontal Center (EVIP) ... the East Valley of Arizona. With two impressive practices in Mesa and Scottsdale, the ... Established in 2003, EVIP is led by founder and practicing periodontist Dr. Todd Jorgenson. ...
Breaking Medicine News(10 mins):
(Date:7/10/2019)... ... July 10, 2019 , ... ... double-blind, placebo controlled clinical study from Ohio State University Wexner Medical Center ... containing urolithins, fulvic acid, and micro minerals. Natreon is committed to continued ...
(Date:7/10/2019)... ... July 10, 2019 , ... DidCBDWork.com is ... for the past 18 months, does CBD actually work? It seems like depending on ... oil. , DidCBDWork.com instead aims to get testimonials of real CBD users, who ...
(Date:7/9/2019)... FALLS CHURCH, Va. (PRWEB) , ... July 10, ... ... Firms, and Their Suppliers, **An interactive workshop presented by Cerulean Associates LLC and ... Bethesda, MD, https://www.fdanews.com/fdadataintegrity , Early Bird Savings: Register by Sept. 23 ...
Breaking Medicine Technology: