Navigation Links
New materials with potential biomedical applications
Date:11/21/2013

Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates were discovered, as their ability to form physical gels in pure water was reported for the first time in a recent study performed in collaboration with the Universities of Jyvskyl and Eastern Finland.

The gelation tendencies of four bisphosphonates were studied in detail under the baton of Academy Research Fellow Elina Sievnen and her group at Department of Chemistry of University of Jyvskyl. Moreover, the structures of the formed gels were investigated in detail by a wide selection of methods. Docent Manu Lahtinen from Department of Chemistry of University of Jyvskyl contributed significantly in the structural analysis part of the study. The examined bisphosphonates were designed and prepared under the supervision of Professor Jouko Vepslinen at the School of Pharmacy of the University of Eastern Finland (Kuopio Campus). The study is part of the doctoral thesis of postgraduate student Aino Alanne from the School of Pharmacy of the University of Eastern Finland.

The current study increases our understanding of the factors affecting on processes leading to gelation and may provide new materials for innovative applications in biomedicine. This kind of materials could, for example, serve as substitutes to restore, maintain, and/or improve the function of bone tissue. Moreover, they might act as scaffolds to mimic the extracellular matrix and provide support for cell adhesion, migration, and proliferation.

The study was published in the prestigious international Journal of Materials Chemistry B: Materials for biology and medicine, and the article was featured in the cover art of issue 45 (2013).

Supramolecular gels are responsive and reversible

Physical, also known as supramolecular, gels form when low molecular mass compounds interact with one another by forming a network, which finally adsorbs the solvent into its structure. Supramolecular gels differ from the traditional chemical (polymeric) gels as being reversible. They can be subjected to a stimulus, e.g. heating, to which they respond by changing forms. After the exposure ceases, the gel is re-formed.

Supramolecular gels have several applications in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.


'/>"/>

Contact: Jouko Vepsäläinen
jouko.vepsalainen@uef.fi
358-403-553-256
University of Eastern Finland
Source:Eurekalert

Related medicine news :

1. No Added Cancer Risk From Hip Replacement Materials: Study
2. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
3. A TECNALIA study reveals the loss of nanomaterials in surface treatments caused by water
4. Aldrich Materials Science discovers liquid-free preparation of metal organic frameworks
5. Contemporary Product Solutions Released their Winter Dental Magazine by Evaluating Dental Products and Dental Materials From a "Total Team" Perspective
6. SFU materials and particle science attract government funding
7. Huntsman Advanced Materials Launches Commercial Acceleration Program with SpecialChem to Support Epoxy Specialty Components Business
8. Spiritual Life Coaching School Holistic Learning Center Releases Official Client Materials
9. UTSA engineering dean C. Mauli Agrawal receives award from Society for Biomaterials
10. Launch of Chinese-German Center for Bio-Inspired Materials at Mainz University Medical Center
11. New Evaluation of the Heart Truth® Professional Education Materials Released
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... The ... Zuckerberg San Francisco General Hospital on April 5-7. The series is a multi-day, ... new habits. The workshops cover a broad range of topics, including coaching skills, ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fisher House Foundation Chairman and CEO ... Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy Kearns Director, VA Southern ... Nevada Healthcare System. This will be the first Fisher House in Nevada, and ...
(Date:2/12/2016)... ... February 12, 2016 , ... Vail knee specialist ... Leaders to Know in 2016 . The list consists of physicians establishing, leading and ... establish this list. , An Ambulatory Surgery Center, also known as an ASC, ...
(Date:2/12/2016)... , ... February 12, 2016 , ... Donor Network West, ... California and Nevada, announced a partnership with San Ramon Regional Medical Center. Under the ... hospital’s facilities as a way to accommodate a more certain time frame for donor ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... surrounding communities by continuing it’s commitment to act as Agents of Change in ... works closely with area homeless families to fulfill immediate needs and help them ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... PRO-DEX, INC. (NasdaqCM: PDEX) today announced financial results ... The Company also filed its Quarterly Report on Form 10-Q ... Securities and Exchange Commission today. --> ... --> --> Net sales for the ... 95%, to $5.4 million from $2.8 million for the three ...
(Date:2/11/2016)... , Feb. 11, 2016   Health 2.0 , ... new health technologies, announced today " 10 Year Global ... health tech over the past ten years.   ... a decade, Health 2.0 has served as the preeminent ... connected with thousands of technologies, companies, innovators, and patient-activists ...
(Date:2/11/2016)... 11, 2016  AfterPill.com is reporting that this week,s ... for all women who are at risk of unintended ... year and raises the risks of unprotected sex in ... According to the Guttmacher Institute, there are 43 ... child-bearing age, who have sex without the intention of ...
Breaking Medicine Technology: