Navigation Links
New made-in-Canada therapy for bladder cancer shows promising results
Date:5/24/2011

Clinical trials for a new bladder cancer therapy show promising interim results. Lead researcher Alvaro Morales says that the breakthrough using the drug Urocidin follows thirty years of his research in this important area.

"I am optimistic about the results of the trial," says Dr. Morales, professor emeritus in the Department of Urology at Queen's University and director of the Queen's University Centre for Applied Urological Research. "Positive results in the next phase of trials will move us very close to a far more effective bladder cancer treatment."

Initial human trials found that Urocidin is effective and much safer than previous treatment options for cases of superficial bladder cancer that is not responsive to Bacillus Calmette-Gurin (BCG) therapy. A recent large North American clinical trial confirmed the initial findings, with 25 per cent of patients becoming disease-free after one year of therapy with the new drug. Patients also tolerated Urocidin well.

Dr. Morales spearheaded BCG as a bladder cancer treatment in the 1970s in collaboration with the Cancer Research Institute of New York. BCG provoked an immune response strong enough to eliminate some bladder cancers without chemicals. It was also the first effective agent approved by the FDA against solid tumors. BCG remains the first choice to treat superficial bladder cancer due to its superior efficacy over chemotherapy drugs, however, as a live bacterium, it has the potential for serious adverse effects.

"There has been a lot of concern about the adverse effects of BCG," explains Dr. Morales. "I've always thought that we should look for something better. Urocidin could be what we're looking for."

Until the discovery of BCG as a bladder cancer therapy, the only alternative short of bladder removal was to put chemicals into the bladder.

Urocidin was developed by Bioniche Life Sciences Inc. A second Phase III clinical trial is underway, f
'/>"/>

Contact: Christina Archibald
christina.archibald@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Nicotine replacement therapy is over-promoted since most ex-smokers quit unassisted
2. Social Anxiety and Panic - Alternative Treatment to Drugs and Therapy
3. Longview Therapy Center, PLLC, Unveils Its Definition Of Hope
4. Short-term radiation therapy successful on breast cancer
5. ASCROs Response to NY Times Articles on Radiation Therapy Incidents
6. Children With Cerebral Palsy Benefitting From New Physical Therapy Regimen
7. DavisPTnetwork Partners with the New York Physical Therapy Association to Provide Online Continuing Education
8. Behavioral therapy improves sleep and lives of patients with pain
9. WHI data confirm short-term heart disease risks of combination menopausal hormone therapy
10. Promising therapy for relapsing multibple sclerosis
11. Split-course palliative radiotherapy confirmed as effective treatment for advanced NSCLC
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New made-in-Canada therapy for bladder cancer shows promising results
(Date:8/27/2015)... Angeles, CA (PRWEB) , ... August 27, 2015 , ... ... that the helpfulness of a doctor is tied directly to the success of a ... patients over a two year period, measured their weight loss over that period, and ...
(Date:8/27/2015)... CA (PRWEB) , ... August 27, 2015 , ... In ... get help, leaving weeks or months later, relapsing and returning again, all at great ... the influence while in sober living homes or soon after leaving facilities who claim ...
(Date:8/27/2015)... , ... August 27, 2015 , ... ... instruments available for quantitative PCR (qPCR) in the last decade. New ... and reduced operating costs. On the flipside, where do lab managers, technicians, and ...
(Date:8/27/2015)... ... August 27, 2015 , ... According to an ... Heart Association have released new guidelines to educate doctors and patients on the best ... these particular guidelines came in 2007, so the new version is taking into account ...
(Date:8/27/2015)... ... 27, 2015 , ... Thriveology Founders, Dr. Carly Letzt Carney and Dr. Mark ... Expo in Denver, Colorado on Saturday, August 29, 2015 at the Marriott DTC, 4900 ... as health authorities, and will present a two part seminar entitled, “How to Thrive ...
Breaking Medicine News(10 mins):Health News:Article on Physician Influence on Weight Loss Highlights the Importance of a Doctor Who Cares, says Dr. Feiz & Associates 2Health News:National Screenings of Documentary Indicate Burgeoning Questions about the Effectiveness of Addiction Treatment Facilities 2Health News:National Screenings of Documentary Indicate Burgeoning Questions about the Effectiveness of Addiction Treatment Facilities 3Health News:Douglas Scientific® Webinar Outlines Comparisons of Varied qPCR Instruments 2Health News:Douglas Scientific® Webinar Outlines Comparisons of Varied qPCR Instruments 3Health News:Article on New Diabetic Care Guidelines Shines Brightly on Weight Loss Surgery, notes Beverly Hills Physicians 2Health News:Article on New Diabetic Care Guidelines Shines Brightly on Weight Loss Surgery, notes Beverly Hills Physicians 3Health News:Internationally-renowned Naturopathic Doctor and Chiropractor Team up to Reveal Secrets of Avoiding Disease 2
... Drug resistance is making many diseases increasingly difficult--and ... M.D., director of the National Institute of Allergy ... Institutes of Health. Extensively drug-resistant tuberculosis and invasive ... recent examples of this problem that pose serious ...
... Week March,10 - 17 unites MS organizations and all ... an effort to shine a spotlight on ways,that we ... someone is,newly diagnosed each hour., (Logo: http://www.newscom.com/cgi-bin/prnh/20010328/NEW004LOGO ... To Join The MS Movement, The National Multiple ...
... APA,s Psychologically Healthy Workplace Awards, ... Nine Honored for Best Practices, ... and making ends meet, three-fourths of Americans,say they are stressed ... of employees reap rewards for employer and employees alike,including benefits ...
... A study by the Woolcock Institute of Medical Research in ... very mild or well-controlled asthma, regular treatment with low dose ... , The study published in this months edition of Primary ... and compared the effects of inhaled corticosteroids (ICS) and placebo ...
... possible to take a simple blood test and predict whether ... predisposing them to the development of Type 2 diabetes. If ... use preventative treatment, slowing down, or even halting that development. ... Sydneys Garvan Institute of Medical Research who have shown conclusively ...
... Essman, Will Ferrell, Tina Fey, Jonah Hill, Kevin James,Conan O,Brien, Rosie O,Donnell, Amy ... Insult Comic Dog And Many More To Be Announced ,Night Of ... $1.99 For 30 Days After Airdate With All Proceeds Going To ... Autism ...
Cached Medicine News:Health News:Confronting the challenge of antimicrobial resistance 2Health News:Confronting the challenge of antimicrobial resistance 3Health News:What Will You Do? Join the Movement to End Multiple Sclerosis During MS Awareness Week March 10-17 2Health News:What Will You Do? Join the Movement to End Multiple Sclerosis During MS Awareness Week March 10-17 3Health News:What Will You Do? Join the Movement to End Multiple Sclerosis During MS Awareness Week March 10-17 4Health News:Top Employers Show Investing In Health and Well-Being Leads to Business Success 2Health News:Top Employers Show Investing In Health and Well-Being Leads to Business Success 3Health News:Top Employers Show Investing In Health and Well-Being Leads to Business Success 4Health News:Treatment for mild asthma leads to improved lung function 2Health News:Low levels of PYY hormone a very early indicator of type 2 diabetes 2Health News:COMEDY CENTRAL(R) Announces Live On-Air Charity Special 'Night Of Too Many Stars: An Overbooked Benefit For Autism Education' Hosted by Jon Stewart on Sunday April 13, at 8 p.m. ET 2Health News:COMEDY CENTRAL(R) Announces Live On-Air Charity Special 'Night Of Too Many Stars: An Overbooked Benefit For Autism Education' Hosted by Jon Stewart on Sunday April 13, at 8 p.m. ET 3
(Date:8/27/2015)...  Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... will be participating in the Goldman Sachs 2015 European ... in London on Thursday, September ... 1927 and headquartered in Warsaw, Indiana ... healthcare.  We design, manufacture and market orthopaedic reconstructive products; ...
(Date:8/27/2015)... 27, 2015 WuXi PharmaTech (Cayman) Inc. (NYSE: ... platform company serving the pharmaceutical, biotechnology, and ... development and manufacturing subsidiary Shanghai SynTheAll Pharmaceutical ... from the Japan PMDA for the manufacture ... commercial drug in July. STA is now ...
(Date:8/27/2015)... , Aug. 27, 2015  Symbiomix today announced ... clinical study, the second pivotal trial of SYM-1219, which ... of bacterial vaginosis (BV). Earlier this year Symbiomix announced ... Symbiomix expects to finish this second pivotal trial by ... Drug Application (NDA) filing with the U.S. Food and ...
Breaking Medicine Technology:WuXi PharmaTech's STA Subsidiary Receives First Approval from Japanese Regulatory Authorities 2Symbiomix Therapeutics Completes Enrollment in Second Pivotal Trial of SYM-1219 for Bacterial Vaginosis, and Receives FDA Fast Track Designation 2Symbiomix Therapeutics Completes Enrollment in Second Pivotal Trial of SYM-1219 for Bacterial Vaginosis, and Receives FDA Fast Track Designation 3Symbiomix Therapeutics Completes Enrollment in Second Pivotal Trial of SYM-1219 for Bacterial Vaginosis, and Receives FDA Fast Track Designation 4
... Texas, July 21, 2011 Assured Pharmacy, Inc. (Other ... medications to more than 3,000 sufferers of chronic pain, ... Pink Current Information with the OTC Markets, using the ... have been posted on the OTC Markets website and ...
... N.J., July 20, 2011 Savient Pharmaceuticals, Inc. (NASDAQ: ... financial results for the second quarter 2011 prior to the ... John H. Johnson, Chief Executive Officer and President, ... will host an investment community conference call beginning at 9:00 ...
Cached Medicine Technology:Assured Pharmacy Upgrades to OTC Pink Current Information 2Assured Pharmacy Upgrades to OTC Pink Current Information 3Savient Pharmaceuticals to Hold Second Quarter 2011 Financial Results Conference Call on Thursday, August 4, 2011 2
... latest addition to the HemoCue glucose product range. ... combines the precision and accuracy of a laboratory ... ease of use. The new pocket size analyser ... date and time for up to 600 measurements. ...
ELISA for the detection of C. difficile toxin A in stool specimens...
... should not suffice, then electronic magnification comes into ... set today. With an electronic television reader, text, ... 70 times. A video camera shows a recorded ... monitor. The television reader has been especially developed ...
... combination of topography, auto-refraction and keratometer in ... devices. The compactness of this instrument is ... space and cost saving solution. Highly ... time and easy handling makes working with ...
Medicine Products: