Navigation Links
New lupus drug results from Scripps Research technology
Date:3/10/2011

LA JOLLA, CA March 9, 2011 For Immediate Release Scientific advances at The Scripps Research Institute were key to laying the foundation for the new drug Benlysta (belimumab), approved today by the U.S. Food and Drug Administration. Benlysta, which treats the most common type of lupus, is the first in a new class of pharmaceuticals that prevents the body from attacking its own critical tissues.

"I am deeply gratified that our scientific findings have proven so valuable to drug discovery," said Richard A. Lerner, MD, president of Scripps Research. "This development underlines the importance of basic academic science in laying important groundwork for life-saving medical advances."

Benlysta, developed by GlaxoSmithKline and Human Genome Sciences, is the first new drug treatment for lupus in 50 years.

Short-Circuiting the Cycle of Lupus

Benlysta was approved for systemic lupus erythematosus, a chronic, life-threatening inflammatory disease affecting the joints, skin, kidneys, blood, heart, and lungs. It is often simply referred to as "lupus" (although there are other types of lupus, including one that affects solely the skin). Estimates of the number of Americans affected by sytemic lupus erythematosus range from 161,000 to 1.5 million, according to the U.S. Centers for Disease Control. Lupus can occur at any age, but first appears largely in 15- to 40-year-olds, the majority of whom are women.

Lupus is an autoimmune disease, which occurs when a person's body produces an immune response against its own tissues instead of solely attacking foreign invaders such as viruses, bacteria, and other toxins.

Symptoms can include debilitating fatigue, painful and swollen joints, fever, skin rash, and kidney problems. The disease can also lead to arthritis, kidney failure, heart and lung inflammation, central nervous system abnormalities, inflammation of the blood vessels, and blood disorders.

Benlysta (itself a type of immune molecule
'/>"/>

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
2. Antibodies linked to cardiovascular disease increase in patients with active lupus
3. New Clues to Lupus Link With Heart Disease
4. Psychotherapy Can Help People With Lupus Cope
5. Sisters Helping Sisters: A New Lupus Research Study to Follow Sisters of Lupus Patients
6. Lupus Awareness Month Kicks Off at Rockefeller Center: EHE International Donates Display Window to S.L.E. Lupus Foundation for May
7. Genealogy may affect clinical differences in systemic lupus erythmatosus patients
8. Chinese systemic lupus erythematosus data reveal differences in epidemiology across continents
9. Researchers uncover biological rationale for why intensive lupus treatment works
10. Overactive Blood Platelets May Play Role in Lupus
11. Correction: Abatacept found ineffective in treatment of non-life threatening lupus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... (PRWEB) March 03, 2015 Human ... that it’s offering a new master health insurance plan ... its clients with a group platform removing potential cost ... Master Health Plan has been in effect since January ... clients with much need medical cost savings. , The ...
(Date:3/3/2015)... March 03, 2015 The authors Tracey Webb ... care for the future is a good and healthy ... UK) the authors have a created an ingenious book that ... vegetarian & vegan meals. , “Crude Food” shows readers ... and allergies, mainly caused by over processed refined foods ...
(Date:3/3/2015)... March 03, 2015 AliCare Medical ... care management programs and a member of the ... of Julie O’Brien as President. O’Brien formerly served ... Officer. In her new role, she will continue ... aspects of AMM’s call center operations, including clinical ...
(Date:3/3/2015)... 03, 2015 Motion 5 ... Environment from Pixel Film Studios. , “inMotion3D Environment is ... into 360° viewing area inside Motion 5” said Christina ... the line between professional and amateur making this plugin ... turn their 2D HDRI images into 360° viewing area ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 ... user-friendly website that focuses on providing an interactive ... schools, and addiction treatment for clients ranging in ... interventions on the site have a wide variety ... spectrum disorders, severe learning disabilities, drug rehabilitation, failure ...
Breaking Medicine News(10 mins):Health News:HCBR Group Offers Master Healthcare Plan through Humana 2Health News:New book ‘Crude Food’ gives readers ingenious ways to create healthy meals 2Health News:New book ‘Crude Food’ gives readers ingenious ways to create healthy meals 3Health News:Julie O'Brien Named President of AliCare Medical Management 2Health News:Julie O'Brien Named President of AliCare Medical Management 3Health News:A New Plugin Entitled inMotion3D Environment Was Released Today from Pixel Film Studios Exclusively for Motion 5 2Health News:All Kinds of Therapy – New Website for Behavioral Health and Substance Abuse Treatment Launches Today 2
... ... 440 Series motorized and mobile medical procedure table that reduces possible healthcare personnel and patient ... (PRWEB) May 10, ... has released the following information about a new mobile procedure table for use ...
... ups risk for early death, and too much could signal illness, ... sleep less than six hours a night are 12 percent more ... to eight hours of slumber, a new study has found. , ... too much -- more than nine hours a night -- doesn,t ...
... ... of our team of Judges and Management Team, iCMG is happy ... Award competition! These international awards along with "John Zachman award for ... for significant achievements in the field of Enterprise and IT Architecture. ...
... Health grant will help University of Central Florida researchers ... by multiple sclerosis and other neurological disorders. Stephen ... and a member of UCF,s Hybrid Systems Laboratory, has ... million project. His team will study the breakdown of ...
... May 2010 Flavour is literally the spice of ... of the table would be unthinkable. Yet just this ... dementias, with patients developing abnormal eating behaviours including changes ... research has revealed evidence that these behaviours are linked ...
... ... Collection is now available at SleepHappens.com. , ... (PRWEB) May 10, 2010 -- Mattress Warehouse is proud to ... Dreamwell Collection is exclusive to Mattress Warehouse and features unique BeautyStyle aesthetics and BeautyFeel ...
Cached Medicine News:Health News:Innovative Motorized and Mobile Medical Procedure Table Developed By MTI, Inc. 2Health News:6 to 8 Hours of Shut-Eye Is Optimal for Health 2Health News:iCMG Architecture Awards for Truly Outstanding Enterprise and IT Excellence 2Health News:iCMG Architecture Awards for Truly Outstanding Enterprise and IT Excellence 3Health News:$1.9 million grant to help UCF find multiple sclerosis 'nerve-ana' 2Health News:Dementia takes away the meaning of flavors 2Health News:Mattress Warehouse Announces Its New Simmons Mattress Lineup 2
(Date:3/2/2015)... , March 2, 2015  DURECT Corporation ... Epigenomic Regulator Program, and the successful completion of ... lead product candidate DUR-928.  DUR-928 is an endogenous, ... broad applicability in metabolic diseases such as nonalcoholic ... and in acute organ injuries such as acute ...
(Date:3/2/2015)... -- Intrexon Corporation (NYSE: XON ), a ... quarter and full year results for 2014.  ... , Acquired ActoGeniX, a European clinical stage biopharmaceutical ... and other innovative products.  Its proprietary TopAct™ platform ... Lactococcus lactis ) to generate biologically-contained ActoBiotics™ for ...
(Date:3/2/2015)... SAN DIEGO, March 2, 2015 Halozyme Therapeutics, Inc. (NASDAQ: ... fourth quarter and full year ended December 31, 2014. Financial ... and a net loss of $5.3 million, or $0.04 per ... net loss of $22.0 million, or $0.19 per share, for ... year 2014 include revenues of $75.3 million and a net ...
Breaking Medicine Technology:DURECT Announces Epigenomic Regulator Program including a New NAFLD/NASH and Acute Organ Injury Product Candidate in Development 2DURECT Announces Epigenomic Regulator Program including a New NAFLD/NASH and Acute Organ Injury Product Candidate in Development 3DURECT Announces Epigenomic Regulator Program including a New NAFLD/NASH and Acute Organ Injury Product Candidate in Development 4DURECT Announces Epigenomic Regulator Program including a New NAFLD/NASH and Acute Organ Injury Product Candidate in Development 5Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 2Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 3Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 4Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 5Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 6Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 7Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 8Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 9Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 10Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 11Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 12Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 13Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 14Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 15Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 16Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 17Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 18Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 19Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 20Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 21Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 22Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 23Intrexon Announces Fourth Quarter and Full Year 2014 Financial Results 24Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 2Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 3Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 4Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 5Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 6Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 7Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 8Halozyme Reports Fourth Quarter And Full Year 2014 Financial Results 9
... CHARLOTTE, N.C., July 25, 2011 A leading international ... patients to ask their dentists about the potential for ... and holders that fasten patients, protective bibs in place. ... Research by Dr. John Molinari, Director of Infection Control ...
... In a comparative pharmacokinetic (PK) study, Upsher-Smith ... topiramate in development for the management of epilepsy ... twice-daily immediate-release topiramate (Topamax®*) in its extent of ... demonstrated a slower absorption profile compared with Topamax®. ...
Cached Medicine Technology:Question Your Dentist About Potential for Cross-Contamination, Leading Infection-Control Scientist Tells Fox News 2PK Study Comparing Upsher-Smith's Extended-Release Topiramate Formulation (USL255) With Topamax® Published Online In Epilepsia 2PK Study Comparing Upsher-Smith's Extended-Release Topiramate Formulation (USL255) With Topamax® Published Online In Epilepsia 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: