Navigation Links
New lung cancer staging system (TNM 7) better predicts local/regional recurrence, study shows
Date:3/31/2011

The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, according to a study published in the April issue of the Journal of Thoracic Oncology.

Being able to better define which patients might experience a cancer recurrence is important, especially given the controversies surrounding the use of adjuvant therapies, particularly postoperative radiation therapy (RT), for patients with non-small cell lung cancer (NSCLC).

In 2009, the International Association for the Study of Lung Cancer (IASLC) published its 7th edition of the tumor, node, metastasis (TNM) classification, which was developed in collaboration with the American Joint Committee on Cancer and the Union Internationale Contre le Cancer. The changes were based on an analysis of a large international database.

Researchers at Duke University School of Medicine in Durham, N.C., analyzed 709 patients who had undergone surgery for non-small cell lung cancer between 1995 and 2005. Stage was assigned based on both TNM 6 and TNM 7. The 5-year actuarial risk of local/regional recurrence (LRR) for all patients was 23%. None of the patients received any adjuvant chemotherapy or radiation therapy.

When patients were converted from TNM 6 to TNM 7, about 13% were placed in a higher stage and 8% in a lower stage. For most malignancies, increasing stage is generally associated with a higher risk of disease recurrence.

Five-year rates of local/regional recurrence for stages IA, IB, IIA, IIB and IIIA disease using TNM 6 were 16%, 26%, 43%, 35% and 40%, respectively. Using TNM 7, the corresponding rates were 16%, 23%, 37%, 39% and 30%.

"The TNM 7 system seems to be a better predictor for LRR after surgery for NSCLC than TNM 6," researchers wrote in the study. "This information may prove to be valuable when designing future studies of postoperative RT."


'/>"/>

Contact: Rene McGaw
renee.mcgaw@ucdenver.edu
303-724-5796
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related medicine news :

1. Soy increases radiations ability to kill lung cancer cells, study shows
2. New therapeutic target for lung cancer
3. U.S. Cancer Rates Continue to Fall
4. US cancer death rates in decline, national report finds
5. Pilot study examines stress, anxiety and needs of young women with a unique breast cancer
6. OHSU Doernbecher discovers new approach to drug resistance in aggressive childhood cancer
7. Attacking bowel cancer on 2 fronts
8. Researchers find possible clues to tamoxifen resistance in breast cancer patients
9. Quitting Smoking Cuts Cancer Risk After Liver Transplant
10. Tet further revealed: Studies track protein relevant to stem cells, cancer
11. Benefits of Radiation Therapy Outweigh Risks of a Second Cancer: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... Inverse Effects of Midlife Occupational and Leisure Time Physical ... occupational physical activity in midlife increases the risk of ... decreases the risk. This is found in a study ... years. The study was conducted at the Gerontology Research ... Health. , Heavy physical labor is often repetitive, wears ...
(Date:4/23/2014)... depletion of self-control, according to research published in ... Psychological Science. , Self-control can be difficult sticking ... a boring textbook are hard things to do. Considerable ... self-control for a long period seems to "deplete" our ... "It is as if self-control is a limited resource ...
(Date:4/23/2014)... of Alzheimer,s disease has been a rapidly evolving ... the latest crook in the research road, scientists ... between proteins associated with the disease. The report, ... Neuroscience , could have important implications for developing ... and colleagues explain that for years, research has ...
(Date:4/22/2014)... industry leaders visited the New Jersey Institute of ... S. Bloom for the launch of the New ... provides a new model for business innovation through ... assets and investment. U.S. Senator Cory Booker, Panasonic ... Taylor, New Jersey Lieutenant Governor Kim Guadagno, New ...
(Date:4/22/2014)... researchers have characterized a set of clock genes that ... types of species, from flies to humans. Over 15 ... there are more. A team from the Perelman School ... big-data approaches could find them. , To accelerate ... professor of Pharmacology and first author Ron Anafi, MD, ...
Breaking Medicine News(10 mins):Health News:Midlife occupational and leisure-time physical activity limits mobility in old age 2Health News:ADHD drug may help preserve our self-control resources 2Health News:Government and industry leaders herald launch of NJIT's New Jersey Innovation Institute 2Health News:Bioinformatics profiling identifies a new mammalian clock gene 2
... networks in fruit flies has led researchers to a sensitive ... most common type of kidney cancer. In the journal ... at the University of Chicago shows that the biomarker known ... renal cell carcinomas but not by normal kidney tissue. , ...
... new 30" in groundbreaking new calendarHAGATNA, Guam, Jan. 27 ... natural calendar to promote her "Look Good Naked" theme ... is beautifully captured au natural and semi-nude in high-quality ... in her beautiful cottage home. "I wanted to show ...
... HCA Healthcare announces the following Webcast:, What: ... 10:00 EST, Where: http://www.videonewswire.com/event.asp?id=55052 , How: ... web at the, ... +1-615 344 ...
... Jan. 27 /PRNewswire-FirstCall/ - QLT Inc. ("QLT") (NASDAQ: ... modified "Dutch Auction" tender offer (the "Offer"), which expired at ... on the preliminary report of the depository for the Offer, ... shares (the "Shares") at a price of US$2.50 per Share, ...
... -- The University of Texas at San Antonio (UTSA) ... College of Engineering has been awarded a $199,884, 24-month ... energy combustion. , "This is one of the first ... combustion, gasification and energy efficiency," said Efstathios Michaelides, mechanical ...
... adds affordable, professionally refurbished Hill-Rom hospital beds to its ... ... -- DRE Medical Equipment — named by Business First of Louisville ... refurbished Hill-Rom hospital beds . DRE’s extensive lineup of economically-priced ...
Cached Medicine News:Health News:Roadkill study could speed detection of kidney cancer 2Health News:QLT announces preliminary results of tender offer 2Health News:QLT announces preliminary results of tender offer 3Health News:UTSA receives federal funding for fossil fuel research 2Health News:DRE Medical Equipment Now Sells Reconditioned Hill-Rom Hospital Beds 2Health News:DRE Medical Equipment Now Sells Reconditioned Hill-Rom Hospital Beds 3
(Date:1/15/2014)... , Jan. 15, 2014 Massachusetts General ... AMGN ) announced today that they ... and validate new therapeutic targets and develop novel ... disorder that affects millions worldwide. The MGH-Broad-Amgen collaboration ...
(Date:1/15/2014)... , Jan. 15, 2014  Humberto C. Antunes,  Galderma  worldwide ... from the Journal of Drugs in Dermatology ... Conference (ODAC). The event is January 17-20, 2014, at the Omni ... . The ODAC is a distinguished ...
(Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers and distributors ... able to protect their most important business assets, ... ) Because of the highly-competitive ... remains one of the most litigious industry sectors ...
Breaking Medicine Technology:Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Intellectual Property Insurance for Medical-related Products and Services 2
... WA – June 25 – MediQuest Therapeutics,Inc., ... for inflammatory and infectious diseases, today announced,the ... of Vascana,– a topical formulation designed to ... primary end point and demonstrated statistical,significance, with ...
... Company updates progress and upcoming,milestones on its ... /PRNewswire-FirstCall/ - SemBioSys,Genetics Inc. , a biotechnology ... metabolic and cardiovascular disease,today announced positive preclinical ... insulin. The Company,presented its findings at the ...
Cached Medicine Technology:MediQuest Concludes Confirmatory Phase III Study of Raynaud’s,Therapy 2SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 2SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 3SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 4
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Medicine Products: