Navigation Links
New lung cancer staging system (TNM 7) better predicts local/regional recurrence, study shows
Date:3/31/2011

The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, according to a study published in the April issue of the Journal of Thoracic Oncology.

Being able to better define which patients might experience a cancer recurrence is important, especially given the controversies surrounding the use of adjuvant therapies, particularly postoperative radiation therapy (RT), for patients with non-small cell lung cancer (NSCLC).

In 2009, the International Association for the Study of Lung Cancer (IASLC) published its 7th edition of the tumor, node, metastasis (TNM) classification, which was developed in collaboration with the American Joint Committee on Cancer and the Union Internationale Contre le Cancer. The changes were based on an analysis of a large international database.

Researchers at Duke University School of Medicine in Durham, N.C., analyzed 709 patients who had undergone surgery for non-small cell lung cancer between 1995 and 2005. Stage was assigned based on both TNM 6 and TNM 7. The 5-year actuarial risk of local/regional recurrence (LRR) for all patients was 23%. None of the patients received any adjuvant chemotherapy or radiation therapy.

When patients were converted from TNM 6 to TNM 7, about 13% were placed in a higher stage and 8% in a lower stage. For most malignancies, increasing stage is generally associated with a higher risk of disease recurrence.

Five-year rates of local/regional recurrence for stages IA, IB, IIA, IIB and IIIA disease using TNM 6 were 16%, 26%, 43%, 35% and 40%, respectively. Using TNM 7, the corresponding rates were 16%, 23%, 37%, 39% and 30%.

"The TNM 7 system seems to be a better predictor for LRR after surgery for NSCLC than TNM 6," researchers wrote in the study. "This information may prove to be valuable when designing future studies of postoperative RT."


'/>"/>

Contact: Rene McGaw
renee.mcgaw@ucdenver.edu
303-724-5796
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1

Related medicine news :

1. Soy increases radiations ability to kill lung cancer cells, study shows
2. New therapeutic target for lung cancer
3. U.S. Cancer Rates Continue to Fall
4. US cancer death rates in decline, national report finds
5. Pilot study examines stress, anxiety and needs of young women with a unique breast cancer
6. OHSU Doernbecher discovers new approach to drug resistance in aggressive childhood cancer
7. Attacking bowel cancer on 2 fronts
8. Researchers find possible clues to tamoxifen resistance in breast cancer patients
9. Quitting Smoking Cuts Cancer Risk After Liver Transplant
10. Tet further revealed: Studies track protein relevant to stem cells, cancer
11. Benefits of Radiation Therapy Outweigh Risks of a Second Cancer: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... 2017 , ... Empower Brokerage, located in Southlake, Texas, intends ... , In February, 2017, Empower Brokerage introduced their new “Performance Partners” program to ... teach how to maximize their sales efforts, as well as how to best ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... stories about real people of God in congregations across the United States. ... Presbyterian minister ordained in 1964 who has served congregations in seven states throughout ...
(Date:3/23/2017)... ... 23, 2017 , ... Demonstrating their commitment to improving health ... departments have been awarded national accreditation through the Public Health Accreditation Board ... network of communities across the nation whose health departments meet rigorous national standards ...
(Date:3/23/2017)... NY (PRWEB) , ... March 23, 2017 , ... 82% of adults are unaware of ... kids do not brush their teeth the minimum two times a day that dentists recommend. ... students missing 51 million hours of school and adults missing 164 million hours of work ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... investment in Los Angeles based healthcare technology company California Healthcom Group (CHG). ... the US, and healthcare arena. With headquarters in California, CHG is a growing, ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Research and Markets has announced the addition of the ... ... capillary electrophoresis market to grow at a CAGR of 7.06% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
(Date:3/23/2017)... Newborns are highly vulnerable to infections ... their young immune systems typically mount weak antibody ... achieving strong vaccine responses in newborn animals, including ... trials — by adding compounds known as adjuvants ... papers, they also describe improved adjuvant formulations that ...
(Date:3/23/2017)... , March 23, 2017 ... from the TACTI-mel trial of IMP321 in combination with ... the first (1mg/kg) cohort experiencing a complete response. Recruitment ... cohort is expected to be fully recruited by Q317. ... the AIPAC breast cancer study are expected mid-year (recruitment ...
Breaking Medicine Technology: