Navigation Links
New link between estrogen and breast cancer
Date:8/24/2007

The female sex hormone estrogen turns on a gene linked to breast cancer, according to new research by Brisbane scientists.

The cancer biology team from UQ's Diamantina Institute for Cancer, Immunology and Metabolic Medicine, believe their finding will help explain the link between breast cancer and high levels of estrogen.

What we've shown is that the ability of estrogen to switch this gene on is important for the growth of breast cancer cells, Diamantina cancer biology research leader Professor Tom Gonda said.

The gene they studied, known as MYB, is found in about 70 percent of all breast cancers and is one of several dozen genes called oncogenes that promote cancer growth.

What's important in breast cancer is the ability of estrogen to turn on MYB rather than there being a mutation in the gene itself, Professor Gonda said.

He said the next step was to take the results, which come from isolated cancer cells grown in the laboratory, and test them in laboratory mice that are a better model for human patients.

We're trying to show directly that MYB can induce cancerous changes in normal breast cells.

Professor Gonda and his colleagues at UQ worked with researchers in Melbourne, Adelaide and the United States and published their findings this month in the prestigious scientific journal Proceedings of the National Academy of Sciences of the USA.

He said a drug that blocks the action of MYB might be used to treat breast cancer in the future but he warned that would take many years of hard work.


'/>"/>

Contact: Professor Gonda
communications@uq.edu.au
61-732-402-524
Research Australia
Source:Eurekalert

Page: 1

Related medicine news :

1. CDC reveals relationship between prepregnant weight and heart defects in infants
2. Link between Constipation and Parkinsons Disease
3. Is there a link between bones and memory?
4. Comparison between warfarin and aspirin
5. Link Between Ear Infections And Asthma
6. Understanding The Link Between Metabolic Syndrome And Drinking Patterns
7. The Link Between High-dose Steroid Use And Heart Disease Questioned
8. No link between blood groups and prostate cancer
9. Link Between Infection And Heart Disease
10. Link between chlorine byproducts and pregnancy risks
11. No link between bad weather and rheumatism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and ... explains one of the most popular and least understood books in the Holy Scriptures, ... puzzling descriptions that have baffled scholars for centuries. Many have tossed it off as ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: , ... to enable prevention of a major side effect of chemotherapy in children. Cisplatin ... patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... , Oct. 5, 2017  In response ... of Oral and Maxillofacial Surgeons (AAOMS) released prescribing ... – to be used as a first-line therapy ... Recognizing the ... AAOMS White Paper "Opioid Prescribing: Acute and Postoperative ...
(Date:10/4/2017)...  According to the Centers for Disease Control and Prevention (CDC), ... Urgent Care is helping communities across Massachusetts , ... offering no-cost* flu shots through the end of the month. ... regulations. ... a flu shot is by the end of October, according to the ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, ... 8th Day Software and Consulting, LLC , and named ... 8th Day Software, based in Tennessee , ... 8th Day expands EnvoyHealth,s service offerings for health care ... "In an interoperable ...
Breaking Medicine Technology: