Navigation Links
New laser technique opens doors for drug discovery
Date:3/15/2011

ng on collaborating with the Bornhop group.

Lasers aid measurement

BSI is deceptively simple. It measures the binding force between two molecules mixed in a microscopic liquid-filled chamber by shining a red laser like those used in barcode scanners through it. When the geometry of the chamber is correct, the laser produces an interference pattern that is very sensitive to what the molecules are doing. If the molecules begin sticking together, for example, the pattern begins to shift.

In the new study, the researchers created synthetic membranes that contained a small protein, called GM1, that is a primary target that cholera toxins bind with in order to get into a cell. When they mixed these membranes with cholera toxin B, they measured a binding force consistent with that obtained by other methods.

The researchers performed similar validation tests with naturally derived membranes and three membrane proteins, one associated with breast cancer, another associated with pain and inflammation and the neurotransmitter GABA known to aid in relaxation and sleep and to regulate anxiety.

When they mixed the membranes containing each of these proteins with molecules known to bind with them, the BSI technique provided measurements that agreed with the values obtained by other methods, the scientists reported.

Patents pending

Vanderbilt has applied for and received three patents on the process and has several other patents pending.

The university has issued an exclusive license to develop the technology to Molecular Sensing, Inc. Bornhop is one of the founders of the start-up and serves as its chief scientist.


'/>"/>

Contact: David F. Salisbury
david.salisbury@vanderbilt.edu
615-343-6803
Vanderbilt University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Minimally invasive surgeries: Laser suturing
2. Laser Technology Might Help Doctors Diagnose Melanoma
3. Lasers ID deadly skin cancer better than doctors
4. Smart lasers could make cancer biopsies painless, help speed new drugs to market
5. Colorful brains, cooling lasers, disease-detecting lights and more
6. Mayo Clinic finds early success with laser that destroys tumors with heat
7. Portable laser devices to improve disease diagnosis
8. Laser may reduce prostate surgerys sexual side effects
9. NIST researchers measure high infrared power levels from some green lasers
10. The Laser Warehouse Increases its Inventory of Used Cosmetic Lasers to Meet Growing Demand
11. Skin Laser and Surgery Specialists Offers New eMatrix™ Treatment for Acne Scarring
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New laser technique opens doors for drug discovery
(Date:3/6/2015)... 06, 2015 The Gluten-Free Certification ... Association, is pleased to announce that Dufflet Pastries, ... has expanded their product line of gluten-free treats ... scrumptious and as satisfying as any of their ... and never contains hydrogenated fats or oils, artificial ...
(Date:3/6/2015)... (PRWEB) March 06, 2015 FCPX developers ... from Pixel Film Studios. , “Pro3rd Hue is a lower ... Austin, CEO of Pixel Film Studios. “Blurring the line between ... , Pro3rd Hue is a set of 30 customizable lower ... X. With Pro3rd Hue, FCPX users can complement any design ...
(Date:3/6/2015)... The producers of Health Briefs TV ... Washington and vicinity. This is a city which is full ... many outdoor activities. It is also a city where healthcare ... hospitals call the city home and provide care from the ... TV program will be broadcast on CBS KLEW-TV during the ...
(Date:3/6/2015)... Fluid Running® Owner, Jennifer Conroyd, an ... Fluid Running® method 3 years ago when ... She hit upon the trifecta of combining matched-bpm music, ... maximum-resistance, deep water running technique. She not only completed ... running workout that made the experience both enjoyable and ...
(Date:3/6/2015)... March 06, 2015 As the Mayo ... be discussed, Ford & Associates Nationwide Legal Services, A.P.C., ... 2015 filed lawsuit: Verduzco v. Daiichi Sankyo, Inc., Case ... California. , “In light of a recently filed ... Benicar to evaluate and explore the Mayo Clinic's Benicar ...
Breaking Medicine News(10 mins):Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 2Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 3Health News:Dufflet Pastries® Impressive Collection of Brownies, Cakes, Pies and Cakelets® Now Includes a Gluten-Free Line Certified By the GFCP. 4Health News:A New Plugin Entitled Pro3rd Hue was Released Today from Pixel Film Studios Exclusively for FCPX 2Health News:The Health Briefs TV Show to Air in Spokane, Washington 2Health News:Fluid Running®, the Revolutionary, No-Impact Running Workout, Expands Nationally with New Training Workshop 2Health News:Fluid Running®, the Revolutionary, No-Impact Running Workout, Expands Nationally with New Training Workshop 3Health News:Mayo Clinic's Benicar Case Study Findings Prompts Commentary from Ford & Associates Nationwide Legal Services in Wake of a Recently Filed Benicar Lawsuit 2Health News:Mayo Clinic's Benicar Case Study Findings Prompts Commentary from Ford & Associates Nationwide Legal Services in Wake of a Recently Filed Benicar Lawsuit 3Health News:Mayo Clinic's Benicar Case Study Findings Prompts Commentary from Ford & Associates Nationwide Legal Services in Wake of a Recently Filed Benicar Lawsuit 4
... biomedical sciences, they are playing a key role: living ... media populating incubators in laboratories around the world. But ... their culture dishes? Under the microscope, different cell lines ... these important research objects stop growing without apparent reason ...
... sunlight may be associated with the development of certain ... by researchers at the National Institute of Environmental Health ... "This study found that women who lived in ... developed an autoimmune muscle disease called myositis were more ...
... BEIJING, July 30 /PRNewswire-Asia-FirstCall/ -- China Medical Technologies,Inc. ... China-based medical device,company that develops, manufactures and markets advanced ... independent internal,investigation and the expected reporting in late August ... year ended March 31, 2009 and the,quarter ended June ...
... are more apt to have joint replacement, study finds , ... protein strongly predict the risk of hip and knee joint ... shows. , The research involved 912 healthy people in Italy, ... knee or hip replacement between 1990 and 2005. Those with ...
... CAMBRIDGE, MA, July 30 /PRNewswire/ - rL Solutions, the ... today that it will be sponsoring the 2009 MITSS ... award at the MITSS 8th Annual Dinner and Fundraiser ... Copley Place Hotel. , MITSS established this award in ...
... , , SAN FRANCISCO, ... the city,s leading privately supported, non-profit animal welfare organization, has launched its ... Whether traveling out of town or staying home, out in the ... and easy reference: http://www.sfspca.org/promotions/summer-health-and-safety.html , ...
Cached Medicine News:Health News:New test for safer biomedical research results 2Health News:Sun exposure may trigger certain autoimmune diseases in women 2Health News:China Medical Technologies Announces the Substantial Completion of an Independent Internal Investigation and Expected Timing of Reporting of Unaudited Financial Results for the Quarter and Fiscal Year ended March 31, 2009 and the Quarter ended June 30, 20 2Health News:China Medical Technologies Announces the Substantial Completion of an Independent Internal Investigation and Expected Timing of Reporting of Unaudited Financial Results for the Quarter and Fiscal Year ended March 31, 2009 and the Quarter ended June 30, 20 3Health News:China Medical Technologies Announces the Substantial Completion of an Independent Internal Investigation and Expected Timing of Reporting of Unaudited Financial Results for the Quarter and Fiscal Year ended March 31, 2009 and the Quarter ended June 30, 20 4Health News:Biomarker Could Predict Severe Osteoarthritis 2Health News:rL Solutions to Sponsor 2009 MITSS HOPE Award 2Health News:The San Francisco SPCA Launches Online Guide for Summer Pet Health & Safety 2Health News:The San Francisco SPCA Launches Online Guide for Summer Pet Health & Safety 3
(Date:3/5/2015)... , March 5, 2015 Vermillion, ... solutions company focused on gynecologic disease, announced today ... results before the market open on Wednesday, March ... and webcast at 8:30am Eastern. Conference Call & ... at 8:30am Eastern/5:30am Pacific Domestic: , 800-753-9057International: , ...
(Date:3/5/2015)... TUSTIN, Calif. , March 5, 2015  BioPhotas, ... energy products that use patented photo-therapeutic technologies to treat ... has partnered with the Semper Fi Fund to provide ... members in need of pain management solutions.  ... reported, "The first Marine who used the Celluma at ...
(Date:3/5/2015)... N.J. , March 5, 2015  Medical ... which specializes in high complexity, state-of-the-art, automated DNA-based ... new Human Papillomavirus (HPV) testing which utilizes cutting ... Each year, approximately 12,000 women are ... United States . Genital Human Papillomaviruses (HPV) ...
Breaking Medicine Technology:Vermillion to Report Fourth Quarter and Year-End 2014 Financial Results and Host an Investor Conference Call on March 25 2BioPhotas, Inc. and the Semper Fi Fund Work Together to Provide Pain Relief to Injured Service Members 2BioPhotas, Inc. and the Semper Fi Fund Work Together to Provide Pain Relief to Injured Service Members 3Medical Diagnostic Laboratories, L.L.C., the Institute for Biomarker Research Announces New HPV Tests 2Medical Diagnostic Laboratories, L.L.C., the Institute for Biomarker Research Announces New HPV Tests 3
... Calif., Dec. 6, 2011 A new study ... clinics across the United States witnessed opiate prescriptions for ... 2008.  Dr. Michael Lowenstein, co-medical director for the Waismann ... , warns that this increase signals the gaining popularity ...
... a pioneer in the innovative treatment of extracorporeal ... that the first patient has been enrolled in ... of the company,s photopheresis technology in the treatment ... An estimated 15,000 new patients worldwide are diagnosed ...
Cached Medicine Technology:Rise in Opioid Use for Abdominal Pain Points to Larger Problem Warns Waismann Method Medical Director 2Rise in Opioid Use for Abdominal Pain Points to Larger Problem Warns Waismann Method Medical Director 3First Patient Enrolled in Therakos Phase Two Study for Treatment of Graft-versus-Host Disease 2First Patient Enrolled in Therakos Phase Two Study for Treatment of Graft-versus-Host Disease 3
... The Z-View Aberrometer is the first ... needs of the dispensing Eye Care Practitioner. ... pending) the Z-View Aberrometer quickly and accurately ... well as sphere, cylinder and axis to ...
... American Industrial Laboratories, Inc. specializes in ... eyebank and laboratory specular microscopes, digital ... camera digital upgrade package. Our software ... image data correlation with rapid image ...
... user friendly computerized medical record system whose ... productivity of the practice as well as ... It provides clinical templates for commonly presenting ... also contains an exhaustive database to cover ...
... The Z-1 applanation tonometer is ... 3Z slit lamp or most "Zeiss" ... provides highly accurate intra-ocular pressure readings. ... the slit lamp and the prism ...
Medicine Products: