Navigation Links
New grant awards aim to prevent autoimmune diseases
Date:9/11/2012

SEATTLE (Sept. 11, 2012) - Benaroya Research Institute at Virginia Mason (BRI) recently received two major grant awards to explore how to regulate the immune system, as part of a nationwide collaborative program to prevent autoimmune diseases. The awards will provide BRI scientists with $4.7 million from the National Institutes of Health to discover molecular mechanisms and new therapy targets through in-depth studies of immune function in cells from research participants in the BRI autoimmunity biorepositories.

"We're committed to working with NIAID (National Institute of Allergy and Infectious Diseases) and the U01 Cooperative Study Group to identify and address key gaps in current research in autoimmunity prevention," said BRI Director Gerald Nepom, MD, PhD. "We're pleased that reviewers and funders of this program have confidence in BRI's ability to play a pivotal role in this initiative, and are looking forward to this important research collaboration."

BRI Associate Director Jane Buckner, MD, will lead a $2.6 million grant to understand how the immune system becomes unbalanced in individuals with autoimmune diseases in order to determine how the immune response might be manipulated to prevent autoimmunity in people.

"Our growing understanding of the genetics of autoimmune diseases has led us to study how alterations in several immune pathways, common to individuals with Type 1 diabetes, multiple sclerosis and Crohn's disease, contribute to a loss of immune balance," said Dr. Buckner. "If we can suppress the components that contribute to these diseases and enhance the correct immune system responses early in the diseases, we can work toward preventing them."

BRI Principal Investigator Paul Bollyky, MD, PhD, will head up a $2.1 million grant to look at how the extracellular matrix (the natural substance that holds cells together in every tissue) affects Type 1 diabetes. "We know little about how the tissue environment
'/>"/>

Contact: Kay Branz
kbranz@benaroyaresearch.org
206-342-6903
Immune Tolerance Network
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
2. Washingtons Life Sciences Discovery Fund awards commercialization grants
3. University of Cincinnati researchers win $3.7M grant from US Department of Defense
4. $9 million grant awarded to UH to study, treat learning disabilities
5. Louisiana Tech University professor earns NSF Early Career Development grant
6. Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks
7. Grant awarded to help improve problem-solving skills for deaf and hard-of-hearing students
8. 2 Grand Challenges Explorations grants for global health
9. Clemson professor awarded nearly $600,000 4-year grant to study language of plants
10. LA BioMed receives Grand Challenges Explorations grant
11. UC San Diego Superfund Research Program receives $15 million grant renewal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... 2014 Mediaplanet announced distribution ... March 12th, a campaign that aims to raise awareness ... with industry leader TEALUX , a premium loose ... the campaign provides readers with educational insight about the ... propel the industry forward and make conscious organic choices ...
(Date:7/28/2014)... Irresistible infants have met their match with a ... online gifting company specializes in homemade chicken noodle soup and creates ... package starts with home-from-the-hospital essentials every new parent will love:, ... rolls , 6 cookies , a ladle ... ready to heat and eat upon delivery, so parents can relax ...
(Date:7/28/2014)... 28, 2014 A St. Jude Children’s ... survivors of childhood cancer more than doubled their risk ... failing to follow a heart-healthy lifestyle. The results appear ... Almost 32 percent of the 1,598 adult survivors of ... umbrella term for health risk factors like high blood ...
(Date:7/28/2014)... Congress 2014 promises to be bigger, better and more ... of the Congress Programme Committee. The European Society of ... event every year in August. Record numbers of Hot ... the congress is on track to host the largest ... why an extra hot line session has been added ...
(Date:7/28/2014)... Taiwan has developed a new optical technology that may ... sooner, when it is more easily treated. If the ... may pave the way for the early detection and ... neuropathy, which is common among people with both Type ... the autonomic nerves controlling vital organs like the heart ...
Breaking Medicine News(10 mins):Health News:Mediaplanet's "Organic Living" Campaign Raises Awareness About What Nature Invented, With the Help of Partner TEALUX 2Health News:Spoonful of Comfort Announces "New Baby" Gift Package 2Health News:Unhealthy Habits More than Double Risk of Metabolic Syndrome in Childhood Cancer Survivors 2Health News:Unhealthy Habits More than Double Risk of Metabolic Syndrome in Childhood Cancer Survivors 3Health News:Unhealthy Habits More than Double Risk of Metabolic Syndrome in Childhood Cancer Survivors 4Health News:ESC Congress 2014 focuses on innovations in cardiology 2Health News:ESC Congress 2014 focuses on innovations in cardiology 3Health News:Wearable device for the early detection of common diabetes-related neurological condition 2
... point out that, consumption of bacon and other processed meat ... ,Dr Dominique S Michaud and other researchers from Boston’s Harvard ... more than 5 portions of bacon every week were more ... by 60% in those who eat bacon regularly, and by ...
... Commonly used drugs that are used in treatment of ... determined by a research, published by the Journal of ... in brain damage. The effects may be long lasting. ... 'chemobrain'.Chemobrain refers to the side effects that are seen ...
... Consumption of milk fortified with specific micronutrients—zinc, iron, ... E—significantly reduce diarrhea and acute lower// respiratory illness ... from the Johns Hopkins Bloomberg School of Public ... Annamalai University in India. The study was published ...
... over laden with salt especially the processed salty snacks instead ... difficulty for them to consume foods with lower concentration of ... intake. ,Disasters like childhood hypertension and early development ... many and can be corrected by reducing the salt content ...
... becoming exceedingly health conscious thus there is a noted ... population. It’s a known fact that moderate// consumption of ... not very safe for any health professional to recommend ... professional says,” I never advocate unrestrained intake. My recommendations ...
... Welfare is procuring a pre-fabricated, self-contained, container based mobile ... of art operation theatre, diagnostic facilities including CT scan, ... generator. ,This container based hospital would be ... road, rail or air to the disaster sites in ...
Cached Medicine News:Health News:Fortified Milk Reduces Morbidity in Preschool Children 2
(Date:7/28/2014)... NORWALK, Conn. , July 28, 2014  UBM ... , a leading online community for medical imaging professionals, ... value in value-based payment models . The ... in identifying how the radiologist,s reimbursement is determined ... article features insight from leaders in the field, who ...
(Date:7/28/2014)... Colo. , July 28, 2014  Array ... financial results for the fourth quarter and ... a conference call to discuss those results ... Chief Executive Officer and Michael Carruthers ... call.Conference Call InformationDate:Tuesday, August 12, 2014Time:9:00 a.m. ...
(Date:7/28/2014)... , July 28, 2014  A prospective study ... Sweden has validated the performance of ... and has associated volumetrically assessed breast density measurements ... Epidemiology, Biomarkers & Prevention (DOI: 10.1158/1055-9965.EPI-13-1219), the ... tool for widespread breast cancer risk assessment," was ...
Breaking Medicine Technology:Diagnostic Imaging Delves into Measuring the Radiologist's Value 2Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 2Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 3Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 4
... Feb. 25, 2011 HASCO Medical, Inc. (OTC Bulletin ... managed healthcare provider that serves patients in Alabama, Florida, ... offering making available an additional 8,000+ products available for ... now makes it easy and affordable for patients throughout ...
... Feb. 25, 2011 NorTech, in partnership with ... announce the winners of its annual Innovation Awards ... most innovative organizations and leaders. This ... awards, representing innovations from a broad range of ...
Cached Medicine Technology:HASCO Medical Expands Online Offering 2NorTech, Crain's Cleveland Business Announce 2011 Innovation Award Winners 2NorTech, Crain's Cleveland Business Announce 2011 Innovation Award Winners 3NorTech, Crain's Cleveland Business Announce 2011 Innovation Award Winners 4NorTech, Crain's Cleveland Business Announce 2011 Innovation Award Winners 5
... Basic Laboratory Needs, Synergy systems produce ultrapure water ... 1 to 1.2 L/min to meet the basic ... incorporates a dual-wavelength UV lamp (185 nm and ... of organic contaminants (< 5 ppb TOC when ...
... speed, stability and durability. Back-lighted Display. ... multiple units of measure, piece counting ... and GLP/GMP/ISO output including date and ... Built-in, motor-driven internal calibration mass for ...
... for speed, stability and durability. Back-lighted ... modes, multiple units of measure, piece ... print, and GLP/GMP/ISO output including date ... Touch-key calibration with external weights only ...
TOPLOAD 3200/0.01G, BL3200H. Touch-key external calibration only. Requires calibration weights (either 2000g or 3000g). 120/240V A/C adapter, Lock-down Ring, In-use Protective Cover....
Medicine Products: