Navigation Links
New genomic test spares patients chemotherapy with no adverse effect on survival
Date:3/22/2012

Vienna, Austria: Testing a breast cancer tumour for its genomic signature can help identify which patients will need adjuvant systemic therapy (additional chemotherapy) after surgery, and spare its use in those for whom it is not necessary, according to the results of a study to be presented to the 8th European Breast Cancer Conference (EBCC-8) today (Thursday). Dr. Sabine Linn, an Associate Professor of Medical Oncology at The Netherlands Cancer Institute, Amsterdam, The Netherlands, will say that this is the first study where such a test has been incorporated in decision-making about adjuvant systemic therapy, and that the results are promising.

Adjuvant chemotherapy is used in order to destroy any microscopic cancer cells that might still be present in the body after surgery. Although it is effective, the side effects can be distressing. "Based on our data, the use of the genomic test could lead to a reduction of nearly 30% in the use of adjuvant chemotherapy without compromising patient outcomes," Dr. Linn will say. "This percentage may vary somewhat due to different guidelines used in different countries. These findings are important both for quality of life and for cutting down unnecessary healthcare costs."

The researchers studied follow-up data from 427 patients with early breast cancer who had taken part in a study called RASTER (MicroarRAy prognoSTics in breast cancER). Their cancers had not yet spread to the lymph nodes (node-negative). By looking for a particular selection of 70 genes in a tumour, the Mammaprint test can predict which patients are at low and which at high risk of distant disease (metastasis); this enables doctors to select which patients could be spared the side effects of chemotherapy without adversely affecting their chances of disease-free survival. The study aimed to assess the feasibility of implementing the test in daily clinical practice in The Netherlands, as well as its effect on adjuvant systemic treatmen
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researcher Uses Genomics to Predict His Odds for Disease
2. VIB and BGI organize joint genomics meeting, Feb. 15, 2012, Belgium
3. Genome Research publishes special issue: Cancer Genomics
4. Traumatic injury sets off a genomic storm in immune system pathways
5. Blood-based genomic test better than imaging test for ruling out obstructive coronary artery disease
6. Toronto-based genomics center gets $5 million injection
7. From genomic data to new cancer drug
8. Dana-Farber, Brigham and Womens launch large-scale genomic database project
9. Structural Genomics Project creates blueprint for infectious disease and biodefense research
10. Lung tumors in never-smokers show greater genomic instability than those in smokers
11. Novel analysis method organizes genomic cancer data
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... Dallas, Texas (PRWEB) July 13, 2014 ... of aGVHD in the 6MM, from 8,062 diagnosed incident ... 2023, at an Annual Growth Rate (AGR) of 4.35%, ... have the highest number of diagnosed incident cases of ... whereas Spain will have the lowest number of diagnosed ...
(Date:7/13/2014)... 13, 2014 According to the Kidney Disease ... step by step guide on what to do to eliminate ... quickly. Vkool writes in its review that readers can easily ... to revitalize their kidney health. Vkool also informs in its ... reverse their damaged kidney functions naturally. The book consists of ...
(Date:7/13/2014)... Hills, California (PRWEB) July 13, 2014 ... Danny Musico has formed a promotional partnership with Aqua ... plant based Omega-3 EPA supplement . The collaboration ... is a celebrity fitness trainer , actor, model, ... Hollywood’s go-to trainer for A-List celebrities, he has prepared ...
(Date:7/13/2014)... Ann Arbor, MI (PRWEB) July 13, 2014 ... online learning program he has just launched at http://www.HealthYourself101.com ... management of visceral obesity. , Power has set out ... and its ill effects that’s actually – dare we say ... , “The program,” says Power, “aims to engage the remote ...
(Date:7/13/2014)... Recently, iFitDress.com, one of the most ... outfits, has added a new selection of beautiful ... has launched a promotion for these evening gowns. Now, ... is now providing thousands of graceful gowns in its ... Britain, America, France, Italy and many other countries. They ...
Breaking Medicine News(10 mins):Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 3Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 4Health News:New and Beautiful Evening Dresses Unveiled by iFitDress.com 2
... , , MILWAUKEE, July 16 ... the nation in two different specialties, according to US News and ... same publication, St. Luke,s and Aurora Sinai Medical Center were recognized by ... , , (Logo: ...
... American Association for Homecare Applauds ,Medicare Home Oxygen ... Confusion, Service Disruption, and Reduced Access to Care for More than ... ARLINGTON, Va., July 16 The American Association for Homecare ... the Medicare Home Oxygen Therapy Act of 2009, which would protect ...
... CAMBRIDGE, Mass., July 16 Biopure Corporation (Nasdaq: ... petition for relief under Chapter 11 of the United States Bankruptcy ... Massachusetts. Biopure will continue to manage and operate its businesses ... the supervision of the Bankruptcy Court. , , ...
... , NORCROSS, Ga., July 16 Immucor, ... providing automated instrument-reagent systems to the blood transfusion industry, today ... and Chief Operating Officer. , , ... have worldwide responsibility for manufacturing and distribution as well as ...
... of problems right away, study notes , THURSDAY, July 16 ... soldiers from the Iraq and Afghanistan wars seen at VA ... a new study shows. , Curiously, the researchers from the ... diagnoses were not made in the first year that a ...
... , , NEW YORK and LOS ANGELES, July ... The Cleaner , with Benjamin Bratt starring as ... show,s co-executive producer Warren Boyd. What,s encouraging about The Cleaner ... the nature of addictive behavior. With more than 23 million Americans ...
Cached Medicine News:Health News:Aurora's Milwaukee Hospitals Recognized in US News and World Report 2Health News:Congressmen Mike Ross and Kendrick Meek Introduce Bill to Protect Medicare Patients Who Require Medical Oxygen Therapy at Home 2Health News:Congressmen Mike Ross and Kendrick Meek Introduce Bill to Protect Medicare Patients Who Require Medical Oxygen Therapy at Home 3Health News:Immucor Appoints Chief Operating Officer 2Health News:Many Veterans Need Mental Health Care 2Health News:Many Veterans Need Mental Health Care 3Health News:Many Veterans Need Mental Health Care 4Health News:Coming Clean About The Cleaner - Phoenix House's Chief Clinical Officer David Deitch on Intervention, and the Recovery Process That Follows 2Health News:Coming Clean About The Cleaner - Phoenix House's Chief Clinical Officer David Deitch on Intervention, and the Recovery Process That Follows 3
(Date:7/11/2014)... ANGELES , July 11, 2014 /PRNewswire-iReach/ -- ... e-liquid, a vegetable-glycol solution for use in portable ... of the active ingredients in cannabis, cannabidiol offers ... personal vaporizer devices, and other vaporizer technology. ... Cannabis naturally contains 483 different compounds which ...
(Date:7/11/2014)... -- Research and Markets has announced the ... Film Industry Report 2014" report to their offering. ... Global And Chinese Medical X-Ray Film Industry Report 2014 ... state of the Global medical X-ray film industry with ... provides a basic overview of the industry including definitions, ...
(Date:7/11/2014)... , July 11, 2014  Australian drug delivery company, ... it has raised A$19.3 million via a placement of ... , the U.S., Asia ... from a share purchase plan (SPP) to be offered ... be made in two tranches. "This capital ...
Breaking Medicine Technology:VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2Global and Chinese Medical X-ray Film Industry Report 2014 2Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3
... Inc. ( www.spirusmed.com ), a leading developer of diagnostic ... of pan-endoscopies in an average time of 60 minutes, ... power a single use spiral component. The initial clinical ... ability to navigate the intestinal tract. ...
... Cantel Medical Corp. (NYSE: CMN ), announced ... medical face masks - the SecureFit™ series by Crosstex ... of medical face masks. The SecureFit™ series of masks ... as a major hindrance to their effectiveness.  Medical face ...
Cached Medicine Technology:Recent Patient Series Demonstrates Spirus Medical's Power Spiral Endoscope Enables Unprecedented Access to GI Tract 2Recent Patient Series Demonstrates Spirus Medical's Power Spiral Endoscope Enables Unprecedented Access to GI Tract 3Cantel Medical Corp. Launches New Medical Face Mask Addressing Issue of Fit 2Cantel Medical Corp. Launches New Medical Face Mask Addressing Issue of Fit 3
Inquire...
Legionella provides rapid, accurate results that aid in the presumptive diagnosis of Legionella infection (Legionnaires' Disease)....
... The advanced design of the ... its sleek, modern configuration, now ... color to complement any office ... designed to integrate into existing ...
The AP250 Auto Projector is a remote-controlled, programmable, random-access, high-resolution, ophthalmic projector....
Medicine Products: