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New genomic marker for tuberculosis may help identify patients who will develop the disease
Date:8/29/2010

sed to monitor how well a patient's treatment is working," said Dr. Ramilo.

Dr. Mejias says that this study highlights the power that gene expression microarray technology could bring to the diagnosis and treatment of infectious diseases, as the blood transcriptional signatures are not limited to TB. Currently, the infectious disease investigators at Nationwide Children's Hospital are developing transcriptional signatures using blood samples obtained from children with broncholitis and pneumonia and plan to correlate findings with clinical outcomes, similar to the recent TB study.

"It seems that we are developing a tool that can not only diagnose infectious diseases, but also indicate severity and eventually predict which patients are at risk for developing advanced symptoms. These capabilities are desperately needed in order to improve how patients recover from infections," said Dr. Ramilo.


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Contact: Mary Ellen Peacock
MaryEllen.Peacock@NationwideChildrens.org
614-355-0495
Nationwide Children's Hospital
Source:Eurekalert

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