Navigation Links
New genetic lineage of Ebola virus discovered in great apes
Date:11/12/2007

This release is available in French.

The Zaire species of Ebolavirus (ZEBOV) remains the most virulent of the various known species. It alone is responsible for 88% of human deaths from haemorrhagic fever recorded since Ebolas discovery in 1976. It was moreover the species involved in the two-month long epidemic which raged in the Democratic Republic of Congo (DRC) .In spite of the mass of scientific data collected during previous epidemics, the international scientific community has still not succeeded in determining the evolutionary development of the Ebolavirus and more particularly that of ZEBOV. Investigations were restricted by the scarcity of available data. Only 12 gene sequences coding for the glycoprotein (GP), a molecular structure that enables the virus to penetrate a cell before infecting it, have currently been identified. Furthermore, these sequences, isolated from infected humans between 1976 and 2001, appear to belong to a single genetic lineage originating from the first epidemic documented in the DRC in 1976. This apparent genetic uniformity therefore suggested that epidemics that broke out after 1976 all stemmed from the very first one. However, recent discoveries by a joint IRD-CIRMF team have called this hypothesis into question.

Between 2001 and 2006, these scientists discovered 47 animal carcasses in Gabon and the Republic of Congo. Among them were the remains of 18 gorillas and 5 chimpanzees. The rapid tissue decomposition of the carcasses meant that the search for RNA sequences coding for GP was conclusive for only 6 gorillas and one chimpanzee. Nevertheless, phylogenetic analysis of these was able to show that the virus which had contaminated the seven primates belonged to a new genetic lineage of ZEBOV. This lineage, named B, showed 2 to 3% genetic divergence from lineage A, the one in which scientists had hitherto classified all the virus
'/>"/>

Contact: Gregory Flechet
fichesactu@paris.ird.fr
33-014-803-7607
Institut de Recherche Pour le Dveloppement
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. Genetic predisposition increases childhood asthma risk
3. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
4. Test Spots Genetic Damage Done by Smoking
5. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
6. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
7. Genetics Hold Promise, Challenges for Cancer Care
8. Researchers genetically engineer micro-organisms into tiny factories
9. Study Questions Genetic Screening for Treatable Diseases
10. Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
11. Genetic variation affects smoking cessation treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... October 25, 2014 TASC (Total ... and other benefits account management services, announces the ... employers save on taxes, reduce administrative workload, and ... tax savings and the efficient handling of complex, ... Suite that best meets their goals and objectives. ...
(Date:10/25/2014)... 2014 The federal judge overseeing ... ) filed against Boston Scientific Corp. in the ... Southern District of West Virginia has denied a ... in a group of cases filed on behalf ... October 21st, U.S. District Judge Joseph R. Goodwin ...
(Date:10/25/2014)... 2014 (HealthDay News) -- Not getting the right amount ... a new study suggests. Those who sleep less ... per night may be more prone to developing the ... report. The study authors concluded that duration and quality ... patients with inflammatory bowel diseases. "Both short and ...
(Date:10/25/2014)... (HealthDay News) -- October,s shorter, darker days can trigger ... according to an expert. People affected by ... tired, lack motivation and even have trouble getting out ... suicide, said Dr. Angelos Halaris, a professor in the ... Chicago Stitch School of Medicine. "Seasonal affective disorder ...
(Date:10/22/2014)... Isabel Healthcare will participate ... (ASAHP) Conference on October 22-24 in Las Vegas, NV. ... a panel discussion on Technology in Health Professions Education ... a diagnostic decision support tool and clinical education platform ... students and clinical learners. The Isabel tools help clinicians ...
Breaking Medicine News(10 mins):Health News:TASC’s New Suites Offer Tax Savings and Protection 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 4Health News:Sleep Duration Linked to Ulcerative Colitis Risk in Study 2Health News:Dark Days Here for Folks With Seasonal Depression 2Health News:Isabel Healthcare to Participate in The Association of Schools of Allied Health Professions (ASAHP) 2014 Conference 2
... for estrogen-sensitive tumor types, study found , , SUNDAY, April ... amounts, increases the risk of breast cancer and particularly ... shows. , The findings, expected to be presented Sunday ... Cancer Research, in San Diego, are followed by a ...
... Spectrometer is suitable for use in ... potentially explosive atmospheres, PITTSBURGH, April ... The MAX300-IGX Industrial Mass Spectrometer,is suitable for use in potentially ... obtained ATEX,approval for installations in Zone 1 areas. The MAX300-IGX ...
... the University of Pennsylvania School of Medicine and Abramson ... the American Association for Cancer Research that combining two ... lines. The team is currently designing a trial to ... is resistant to many chemotherapies and to cell-death inducing ...
... Calif., April 12 Over 300,healthcare workers at Coastal ... SEIU United Healthcare Workers - West (UHW) in a,secret-ballot ... "Uniting with thousands of other caregivers as a ... difference on the things that matter most," said,Ruth Calderon, ...
... YMCA Healthy Kids Day Saturday, April 12 ... Calif., April 11 The Mt. Diablo Region,YMCA will join ... Kids Day on Saturday, April 12 from 9 a.m. to ... Irvin Deutscher Family YMCA.,An opportunity for kids and families to ...
... researchers got paid but more upset when they owned ... volunteers in clinical studies aren,t overly concerned if researchers ... trust, suggests a U.S. study. , "Though peoples, willingness ... not suffer substantially based on the types of financial ...
Cached Medicine News:Health News:Drinking May Raise Breast Cancer Risk 2Health News:Extrel CMS Announces ATEX Approval for Process Mass Spectrometer 2Health News:Penn researchers find targeted therapy combination overcomes treatment resistance in liver cancer 2Health News:Coastal Communities Hospital Workers Join United Healthcare Workers 2Health News:The Mt. Diablo Region YMCA Invites Families to 'Put Play in Your Day' and Bring Healthy Habits Home During the Nation's Largest Health Day for Children and Families 2Health News:The Mt. Diablo Region YMCA Invites Families to 'Put Play in Your Day' and Bring Healthy Habits Home During the Nation's Largest Health Day for Children and Families 3Health News:Clinical Trial Volunteers Uneasy About Some Financial Ties 2
(Date:10/25/2014)... --  Metanome, Inc. , a Houston ... was the genomic sequencing provider for Seres Health,s ( ... of SER 109, an Ecobiotic® therapeutic for the treatment ... (CDI). Metanome has provided genomic sequencing services ... Such genomic characterization has enabled the study of the ...
(Date:10/25/2014)... 2014 Best Practices designed the Medical ... a forum for sharing insights about the key ... mechanism for creating and sharing solutions through three ... from the Medical Affairs Consortium survey. ... the first roundtable of the 2014-2015 Medical Affairs ...
(Date:10/22/2014)... 22, 2014  Rescheduling of hydrocodone combination products ... pain market, according to a new primary market ... providing market research and consultation exclusively in the ... http://photos.prnewswire.com/prnh/20141021/153440 In August, ... combination products from Schedule III to Schedule II ...
Breaking Medicine Technology:Metanome Selected as Metagenomics Provider for Seres Health Clinical Trial 2Strong Participation in Best Practices' Medical Affairs Consortium Survey 2Hydrocodone: Rescheduled, Repositioned & Reinvented 2Hydrocodone: Rescheduled, Repositioned & Reinvented 3
... COLLEGEVILLE, Pa., March 30, 2007 /PRNewswire-FirstCall/ --,Wyeth ... Inc. and Lundbeck A/S presented clinical study,results ... this,week. Safety analyses suggest bifeprunox, an investigational,treatment ... with a favorable weight and lipid profile, ...
... is STD Awareness Month: Time to Pay Attention ... 2007 /PRNewswire/ -- During,National Sexually Transmitted Disease (STD) ... awareness of, and,testing for, trichomoniasis (also known as ... States. Awareness of the condition,remains low, despite the ...
Cached Medicine Technology:Safety Analyses of Clinical Data for Bifeprunox in Patients with,Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar,to Placebo 2Safety Analyses of Clinical Data for Bifeprunox in Patients with,Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar,to Placebo 3Safety Analyses of Clinical Data for Bifeprunox in Patients with,Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar,to Placebo 4Safety Analyses of Clinical Data for Bifeprunox in Patients with,Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar,to Placebo 5Safety Analyses of Clinical Data for Bifeprunox in Patients with,Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar,to Placebo 6Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million,Annually 2Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million,Annually 3
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Medicine Products: