Navigation Links
New generation asthma drug could improve metabolism
Date:6/5/2011

Formoterol, a new generation asthma medication, shows great promise for improving fat and protein metabolism, say Australian researchers, who have tested this effect in a small sample of men. The researchers presented their results on Saturday 4 June 2011 at The Endocrine Society's 93rd Annual Meeting in Boston.

The research team comprises members of Professor Ken Ho's lab from Sydney's Garvan Institute of Medical Research as well as Professor Ric Day, a clinical pharmacologist from St. Vincent's Hospital.

Study leader, endocrinologist Dr Paul Lee, focused his PhD research on how various hormones affect metabolism. Of central importance is a class of hormones called catecholamines, which regulate heart rate, metabolism and breathing.

Formoterol is a synthetic catecholamine, the metabolic effects of which have not previously been studied in people. Therapy doses given to animals, however, have shown that it stimulates metabolism without affecting the heart.

"We have known for a long time that catecholamine influences the way the body handles nutrients, in particular fat and protein," said Lee.

"The generation of drugs before formoterol was exploited in the livestock industry around 20 years ago to reduce the fat and increase the protein content of meat. Unfortunately, these older drugs also caused a faster heart rate."

"Formoterol is a new generation of this class of medication. It is highly selective for the kind of catecholamine receptors found in the lungs, and not those in the heart."

"The new drug is also more selective for a similar receptor found in muscle and fat. In theory at least, it should have beneficial metabolic effects like the older class of medication without affecting the heart."

Lee sourced the drug in its oral form, found the dose needed to give a metabolic effect, and gave it to 8 healthy men over a week.

"Energy metabolism increased by more than 10%, fat
'/>"/>

Contact: Alison Heather
61-292-958-128
Research Australia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 30 Years Into the Epidemic, a Generation With HIV Comes of Age
2. Fetal programming of disease risk to next generation depends on parental gender
3. Columbia researchers work to prevent blindness from age-related macular degeneration
4. Targeted regeneration could be key to boosting coalfield communities
5. Mayo Clinic finds new genetic cause of neurodegeneration
6. In vivo RNAi screening identifies new regulators of liver regeneration
7. AACR and Landon Foundation support the next generation of researchers with INNOVATOR Awards
8. Mothers obesity may lead to infertility in the next generation
9. LRI awards wide-ranging research grants to drive next generation of scientific discovery in lupus
10. BNCT, a new-generation radiation treatment, is effective in advanced head and neck cancer
11. In search of cancers common ground: A next-generation view
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/2/2014)... (PRWEB) August 02, 2014 Apervi, ... orchestration platform simplifying data engineering for big data, ... is one of the first Enterprise data engineering ... Spark. Databricks, the company founded by the creators ... as a means to encourage new development on ...
(Date:8/2/2014)... (PRWEB) August 02, 2014 CEDR ... nation's number one provider of customized medical and dental ... major dental-industry conferences this fall. CEDR’s CEO will be ... September and early December. , From September 4-6, CEDR ... Office Managers (AADOM) Dental Managers Conference in San Diego, ...
(Date:8/1/2014)... Recently, iFitDress.com, one of the most famous dress suppliers ... top bridesmaid dresses online. At the moment, all the ... 52% off. According to the company’s senior spokesman, the special ... The company’s stock is limited. Those who are thinking of ... soon as possible. All its products are delicately made by ...
(Date:8/1/2014)... in St. Louis helps explain why brain tumors occur ... than similar tumors in females. For example, glioblastomas, the ... often in males, who suffer greater cognitive impairments than ... researchers found that retinoblastoma protein (RB), a protein known ... male brain cells than in female brain cells. , ...
(Date:8/1/2014)... 2014 Stryker hip lawsuits ( ... 2012 Rejuvenate and ABG II Modular-Neck Hip Stem ... Bergen County Superior Court, Bernstein Liebhard LLP reports. ... Court has issued a Final Amended Stipulated ... hard copy and electronic materials produced by any ...
Breaking Medicine News(10 mins):Health News:Databricks Certifies Apervi Conflux Director TM on Spark, Supercharging the Data to Insight Journey 2Health News:Databricks Certifies Apervi Conflux Director TM on Spark, Supercharging the Data to Insight Journey 3Health News:Nuanced Media Client, CEDR HR Solutions, to Speak at Upcoming Major Dental Conferences 2Health News:Nuanced Media Client, CEDR HR Solutions, to Speak at Upcoming Major Dental Conferences 3Health News:iFitDress.com: Top Bridesmaid Dresses For The Global Customers 2Health News:Study reveals one reason brain tumors are more common in men 2Health News:Stryker Hip Lawsuit News: New Order Issued in New Jersey Stryker Hip Recall Litigation, Bernstein Liebhard LLP Reports 2Health News:Stryker Hip Lawsuit News: New Order Issued in New Jersey Stryker Hip Recall Litigation, Bernstein Liebhard LLP Reports 3
... inflammation and loss of cartilage in joints, is likely ... // ,Researchers led by David Felson, a professor ... with symptomatic osteoarthritis of the knee for 30 months. ... the online edition of BBC News. ,The ...
... for capacity Building', Ministry of Health and Family ... Rs. 1.50 crores or actual, whichever is less, ... State Hospitals of towns/cities located on National Highways. ... Road Transport and Highways and Ministry of Health ...
... an amazing figure at the cost of their own health. ... large population is opting for laxative abuse. ,Assumptions about ... which proved that 20% of women who wanted to lose ... students. ,Though these women start with few pills a ...
... 9th of November, urging parents to prevent use of fluoridated ... dentists are concerned about the exposure to fluoride at such ... teeth it might permanently damage them, apart from which it ... cancer boys. ,This advice is not noticed by many ...
... of food poison. Then, fame came as a temporary ... 'miracle poison' and used for an increasing number of ... Mayo Clinic Health Letter covers how this drug works ... ,Botulinum toxin blocks communication between nerves and muscles. Food ...
... the increasing number of children pronounced as juvenile diabetics, it ... such diseases //on their little ones. What used to ... silently attacking children, and it is imperative that parents and ... hand. ,New data from the International Diabetes ...
Cached Medicine News:Health News:Laxatives are Not the Right Option for Losing Weight 2
(Date:8/1/2014)... 1, 2014 According to ... (Traditional Wound Closure, Anti infective), Basic (Films, Cleansing), Advanced ... Skin Substitutes), Pressure Relief Devices, NPWT) - Global ... Care Market is expected to reach $18.3 Billion ... at a CAGR of 3.2% from 2014 to ...
(Date:8/1/2014)... MEETING, Pa. , Aug. 1, 2014 ... it will host a conference call to report its ... 2014 at 9:00 AM ET. CEO Dr. J. ... will discuss second quarter earnings, provide a corporate update, ... update will include clinical development plans for VGX-3100, Inovio,s ...
(Date:7/31/2014)...  According to data released today by the Centers ... Medicare Part D premium is expected to remain stable ... projected, the Pharmaceutical Care Management Association (PCMA) said. ... a bright spot in American health care. By offering ... using cutting edge, cost-saving tools like pharmacy networks and ...
Breaking Medicine Technology:Wound Care Market Worth $18.3 Billion by 2019 2Wound Care Market Worth $18.3 Billion by 2019 3Inovio Pharmaceuticals to Host Second Quarter 2014 Financial Results Call on August 11, 2014 2Inovio Pharmaceuticals to Host Second Quarter 2014 Financial Results Call on August 11, 2014 3
Stainless steel bone clamp....
Designed for proximal femoral elevation in total hip replacement or in other surgery with a similar need for bone manipulation....
To elevate, dissect, scrape and apply traction to bone and soft tissue....
The AV Plus DX pacing lead is designed for use with the St. Jude Medical Affinity VDR pulse generator. This single-lead pacing system provides reliable pacing therapy with the added benefits of AV sy...
Medicine Products: