Navigation Links
New form of stem cell communication rescues diseased neurons
Date:2/1/2010

LA JOLLA, Calif., February 1, 2010 -- Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research), the Karolinska Institutet, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School and Universit Libre de Bruxelles have demonstrated in mouse models that transplanted stems cells, when in direct contact with diseased neurons, send signals through specialized channels that rescue the neurons from death. These direct cell-to-cell connections may also play a role in normal development by laying down the blueprint for more mature electrical connections between neurons and other cells. The research was published in the journal Proceedings of the National Academy of Sciences on February 1.

While it was already known that stem cells will seek out diseased cells in the brain, the international group of scientists showed, both in tissue culture and in mice, that the stem cells actively bring diseased neurons back from the brink via cross-talk through gap junctions, the connections between cells that allow molecular signals to pass back and forth. Significantly, the stem cells do not need to differentiate into the specific type of neuron to provide this therapeutic effect. The researchers also believe this protective mechanism may be active in other cell types and play a role in many diseases. For example, some of their preliminary work shows that these mechanisms may rescue damaged neural fibers in adult spinal cord injuries.

"We showed a while ago that stems cells may exert a therapeutic effect on damaged or diseased host systems by secreting therapeutic factors and 'bathing' the dying cells," said Evan Snyder, M.D., Ph.D., director of the Stem Cell and Regenerative Biology program at Sanford-Burnham. "However, we did not know that stem cells can also exert their action through direct cell-to-cell contact. Indeed, we believe that this may be a newly-recognized way in
'/>"/>

Contact: Josh Baxt
jbaxt@burnham.org
858-795-5236
Sanford-Burnham Medical Research Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. IABC Cleveland Presents The Changing Face of Health Care Communications at Feb. 18 Luncheon
2. Gordon S. LaVigne Appointed ALS Association Chief Development and Communications Officer
3. Emerson Network Power Unveils DP40 Power Supply Series for Medical, IT and Telecommunications Applications
4. Huntington Hospital Uses New Technology to Assist Nurses; Voalte iPhone Application Improves Critical Communication at Point-of-Care
5. Music therapy can assist toddlers communication rehabilitation process
6. Lifespace Communities Selects StaffKnex Software for Nurse Scheduling and Employee Communications
7. New Report Examines the Role of Communications Technologies in Humanitarian Crises
8. Wisconsin Department of Transportation Chooses EF Johnson Technologies, Inc. for Statewide First Responder Communications System in $13.2 Million Contract
9. LodgeNet Interactive to Participate in UBS 37th Annual Global Media and Communications Conference
10. Live Webinar: Pandemic + Recession = Webcasting: Cost-Effective Streaming for Public Health Communications
11. Lexi-Comp Focused on Improving Patient Communication in Healthcare Institutions Treating Diverse Patient Populations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... May 03, 2015 NuevaCare announced today ... two upcoming area seminars. The first event will take ... Regional Stroke Conference to be held at The Magnolia ... Wednesday, May 13 during the Dementia Conference to be ... “These seminars offer an excellent opportunity to learn about ...
(Date:5/3/2015)... HealthPostures, a pioneering ergonomics company that ... the , May 5 - 7, 2015 Minnesota Safety ... the conference include its bestselling TaskMate sit stand solutions. ... 6100 TaskMate Executive. Features of the 6100 TaskMate Executive ... extended platform work surface and supply holders. Weighing 50 ...
(Date:5/2/2015)... May 02, 2015 Vancouver fencing company, QS ... provide valuable advice to prospective clients related to their questions ... to install railings around their decks and patios. While that ... that pop up once the person rolls up their sleeve ... installing a railing in finding a gate that matches it. ...
(Date:5/2/2015)... (PRWEB) May 02, 2015 It’s a ... deadly natural disaster strikes anywhere on this planet, cyber ... human sympathy and compassion for their own personal gain. ... Computer Emergency Readiness Team) issued an alert titled ... potential email scams citing the earthquake in Nepal. The ...
(Date:5/2/2015)... Ohio (PRWEB) May 02, 2015 On ... Liverpool City Hospital (ELCH) gathered to celebrate improvements in ... River Valley Health Partners (RVHP), had zero acquired ventilator ... urinary catheter associated infections. ELCH was also recently named ... The management team at ELCH credited the teamwork of ...
Breaking Medicine News(10 mins):Health News:NuevaCare Introduces MnemeTherapy® Approach to Care for Elderly Patients with Alzheimer’s, Stroke and Other Types of Neurodegenerative Conditions 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2
... lower risk of ischemic heart disease or stroke. They remain ... to consume more alcohol., ,This research was reported in ... Health., ,Researchers for the study had said that milk ... of its association with cholesterol levels. However people should not ...
... out that sex differences in sleep patterns do exist, with ... carried out a national survey of 39,588 people of the ... of Taiwan. The researchers considered several factors other than gender ... ,The results of the study had shown that there is ...
... reported that in manning the progress of osteoarthritis// of the ... hip involves joint space narrowing that is accompanied by severe ... lead to total hip replacement operation in patients who may ... process of disease progression. ,The researchers had studied ...
... coughs for months or even// years have a high possibility ... the researchers of Montefiore Cough Center, US, have reported that ... average of nine years, 53% of them were also suffering ... Thoracic Society International Conference 2005. ,The researchers did a ...
... scientists have reported that delaying pregnancy may result in ... and more women deciding to put off pregnancy for ... pregnancy for women across the globe. Delaying in getting ... abnormal number of chromosomes, and other conditions. This is ...
... The Lancet that for identifying the risk of breast cancer ... their families, MRI scanning does score more than mammography. ... breast cancer are predisposed to the disease genetically. These women ... adulthood. Screening young women for this purpose is done more ...
Cached Medicine News:
(Date:4/30/2015)... MOUNTAIN VIEW, Calif., April 30, 2015 Omnicell, Inc. ... and supply management solutions to healthcare systems, today announced ... GAAP results: Revenue for the first quarter ... 14.2% from the first quarter of 2014, and down ... 2014. First quarter 2015 net income as ...
(Date:4/30/2015)... VIEW, Calif. , April 30, 2015  IRIDEX ... will release its first quarter 2015 financial results after ...   In conjunction with the release, the Company will ... 5:00 p.m. Eastern Time on Thursday, ... the quarter and other business developments. Interested ...
(Date:4/30/2015)... PLEASANTON, Calif. , April 30, 2015  Thoratec ... mechanical circulatory support therapies to save, support and restore ... Bank of America Merrill Lynch 2015 Healthcare Conference on ... , President and Chief Executive Officer, will provide an ... Daylight time (1:40 p.m., Eastern Daylight Time). ...
Breaking Medicine Technology:Omnicell Announces First Quarter 2015 Results 2Omnicell Announces First Quarter 2015 Results 3Omnicell Announces First Quarter 2015 Results 4Omnicell Announces First Quarter 2015 Results 5Omnicell Announces First Quarter 2015 Results 6Omnicell Announces First Quarter 2015 Results 7Omnicell Announces First Quarter 2015 Results 8Omnicell Announces First Quarter 2015 Results 9Omnicell Announces First Quarter 2015 Results 10Omnicell Announces First Quarter 2015 Results 11Omnicell Announces First Quarter 2015 Results 12Omnicell Announces First Quarter 2015 Results 13Omnicell Announces First Quarter 2015 Results 14Omnicell Announces First Quarter 2015 Results 15Omnicell Announces First Quarter 2015 Results 16Omnicell Announces First Quarter 2015 Results 17Omnicell Announces First Quarter 2015 Results 18Omnicell Announces First Quarter 2015 Results 19Omnicell Announces First Quarter 2015 Results 20Omnicell Announces First Quarter 2015 Results 21Omnicell Announces First Quarter 2015 Results 22Omnicell Announces First Quarter 2015 Results 23Omnicell Announces First Quarter 2015 Results 24Omnicell Announces First Quarter 2015 Results 25Omnicell Announces First Quarter 2015 Results 26Omnicell Announces First Quarter 2015 Results 27IRIDEX Announces First Quarter 2015 Conference Call and Release Date 2Thoratec Presentation At Bank Of America Merrill Lynch Healthcare Conference To Be Webcast 2
... The Pharmaceutical Research and Manufacturers of America (PhRMA) today ... Board of Directors. "We are pleased to ... of Directors," said PhRMA President and Chief Executive Officer ... most research-intensive sectors in the U.S., they bring to ...
... Spectros white LED patent was validated during reexamination by the ... In a reexamination of U.S. Patent No. 6,711,426, the ... in medical spectroscopy is unique and protectable, and that certain ... under this Spectros patent. "This is a broad ...
Cached Medicine Technology:PhRMA Elects Four New Members to Board of Directors 2PhRMA Elects Four New Members to Board of Directors 3Spectros White LED Patent Scope Affirmed In U.S. Patent Office Reexamination 2
... great versatility in epilation and the ... compactness and easy-transportability of the system. ... developed for Smartepil II plus, and ... for hair removal of tricky areas ...
... new and efficient method applied to dermatological ... ongoing research and development with hundreds of ... light source, but rather a platform for ... horizons in pulsed-light-based technology, the most valid ...
Auto Refkeratomoeter...
The convenience of safe and precise Patient Controlled Analgesia in a flexible system designed with advanced technology. This is progressive, innovative, and effective pain management in a sophistica...
Medicine Products: