Navigation Links
New form of endoscopic scanning improves detection of precancerous condition
Date:4/12/2010

>"Barrett's esophagus often develops in individuals who suffer from heartburn and gastrointestinal reflux disease [GERD] which occurs when stomach acid flows backward into the esophagus," explains Ram Chuttani, MD, Director of Interventional Gastroenterology and Endoscopy at BIDMC and a coauthor of the study. "Over time, repeated exposure to stomach contents can result in further progression of the precancerous nature of Barrett's. Known as dysplasia, these precancerous changes occur on a cellular scale, and can currently only be diagnosed by staining numerous cell samples taken from multiple biopsies of different parts of the esophagus," he adds, noting that in spite of multiple biopsies, dysplasia and even cancer may be missed due to inherent sampling errors that can occur when tiny samples are obtained from large surface areas.

The new EPSS instrument, developed by Perelman, enables the endoscopist to more thoroughly search for these dysplastic changes on a subcellular scale. EPSS works by using light-scattering spectroscopy, an optical method that relates color of reflected light to the size, shape and refractive index of the illuminated particle.

"The idea behind light scattering spectroscopy is rooted in the same principles as the formation of a rainbow," explains Perelman. "In a rainbow, white light from the sun is refracted and reflected by tiny water droplets in the atmosphere, which form a colorful spectrum which you see with your eyes. Light scattering spectroscopy employs a bright arc lamp in place of the sun, targets epithelial cells and cell nuclei instead of water droplets, and is viewed through a spectrometer rather than just the human eye. In the case of EPSS, instead of viewing a beautiful arc, the information obtained from these spectra tells us whether or not the esophageal cells we are viewing are dysplastic.

A clinically useful technique in the detection of dysplasia in Barrett's esophagus must rapidly survey a compa
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Why does percutaneous endoscopic gastrostomy fail to eliminate gastroesophageal reflux?
2. ASGE issues guidelines on management of antithrombotic agents for endoscopic procedures
3. Chronic sinusitis patients experience improved quality of life after endoscopic sinus surgery
4. New endoscopic treatment may spare Barretts esophagus patients from surgery
5. Endoscopic resection of a large ileal lipoma
6. A new endoscopic technique for gastrointestinal perforations: the over-the-scope-clip
7. New e-Forms Management Tools from Access Bridge the Gap Between MEDITECH Magic and Scanning and Archiving for Hospitals
8. SecureWorks Extends PCI Approved Scanning Vendor Solutions
9. Scanning for skin cancer: Infrared system looks for deadly melanoma
10. News brief: Contrast agent with MRI improves detection of lymph nodes metastases
11. Nuclear Power Plant Improves Site Security with Blast Resistant Guard Booth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... -- Planning on seconds at Thanksgiving Day dinner this ... as gastroesophageal reflux disease (GERD) -- a few steps may ... nose and throat specialist at Lenox Hill Hospital in New ... on Thanksgiving: Pace yourself. Rather than ... throughout the day. It,s also a good idea to have ...
(Date:11/28/2014)... Austin, Texas (PRWEB) November 28, 2014 ... of prediabetes testing and treatment, helped employees learn ... complimentary on-site diabetes blood screening at a local ... Stop Diabetes @ Work initiative. , As ... @ Work program , PreDiabetes Centers is co-hosting ...
(Date:11/28/2014)... 2014 Mabel’s Labels , the ... and an award-winning company established by four moms, today ... and Tricia Mumby have been honored with a 2014 ... the PROFIT Award for Excellence in Entrepreneurship. , All ... Tricia Mumby) accepted the award on behalf of Mabel’s ...
(Date:11/28/2014)... UniWigs.com, a leader in the wig industry, has ... the next Monday. This promotion features: , > ... up to 70% off (no coupon code needed), ... shipping on orders over $49 , Visit http://www.uniwigs.com for ... Nov. 28th to Dec. 1st and the first 100 shoppers each ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 "Most of my ... me to use crutches," said an inventor from Findlay, Ohio. ... convenient way to support my foot, which inspired me to ... to offer a convenient way to support an injured foot. ... around. It eliminates the need for crutches. The design redistributes ...
Breaking Medicine News(10 mins):Health News:Don't Let Chronic Heartburn Spoil Your Thanksgiving Feast 2Health News:PreDiabetes Centers Offers Workplace Diabetes Screening at Local School 2Health News:Mabel's Labels’ Co-Founders Named A Winner In The 2014 RBC Canadian Women Entrepreneur Awards Program; A Second-Time Win For The Brand 2Health News:Mabel's Labels’ Co-Founders Named A Winner In The 2014 RBC Canadian Women Entrepreneur Awards Program; A Second-Time Win For The Brand 3Health News:Pre-X'mas Crazy Sale Starts from $0 at UniWigs.com 2
... 28 A few spaces remain for the U.S. ... on Nov. 4-5, 2009. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ) ... and journalists and will focus on how FDA employs ... This year,s symposium will feature an address by FDA ...
... inflammatory diseases, researchers say , WEDNESDAY, Oct. 28 (HealthDay ... that fish oils benefit people with rheumatoid arthritis and ... an ingredient in fish oils called DHA into a ... can lead to various diseases, the scientists from Queen ...
... get a boo-boo, we might know to put a bandage on ... it all better. But, what if something happens to our ... for dental emergencies can quickly get back to smiling again. , ... http://inr.mediaseed.tv/oneClip_C/?feed=Ss8P5Rb1iQulYDAELUR0M_kpwKp_6YSM , Medialink is a division of ...
... , What Women Want, Think Should Be Done and at ... new poll released Wednesday by the Independent Women,s Forum ... should be Congress,s top priority and that a majority (51 percent) ... the proposals being considered today. The poll, conducted by WomanTrend, ...
... Collagen Matrix, Inc., the leader in collagen- and mineral-based ... Company,s Founder, President, and Chief Executive Officer was named ... Year category of the 2009 New Jersey Business of ... Certified Public Accountants and Consultants. All finalists will ...
... 28 Atlanta-based Webmedx , the fourth ... of black market sales of medical records in India as ... most reliable way to maintain standards of privacy and security. ... stringent rules for protected health information, the onus on transcription ...
Cached Medicine News:Health News:New Clues to How Fish Oils Help Arthritis Patients 2Health News:Just Released -- New Poll: Healthcare Through Women's Eyes 2Health News:Shu-Tung Li, Founder and CEO of Collagen Matrix, Inc. Honored as 2009 New Jersey Executive of the Year Finalist and Company Named One of Fifty Fastest Growing Companies 2Health News:Webmedx Reacts to News of Confidential Medical Records Being Sold on the Black Market 2
(Date:11/28/2014)... Chinese magnesium alloy maker DongGuan Eontec Co., ... alloy bone fixation screw has received Chinese regulatory inspection ... instrument and that the company acknowledges receipt of the ... Science and Technology Daily journalists Wang Xiangming and ... founder, Professor Li Yangde , has been a ...
(Date:11/27/2014)... 27, 2014 Hovione announced today ... Application with the U.S. Food and Drug Administration (FDA). ... developing improved drug delivery options for established drugs. ... novel formulation using a new patented crystalline base form ... widely prescribed oral antibiotics for acne. Currently, there are ...
(Date:11/26/2014)... 2014   Royal Philips (NYSE: ... availability of its portfolio of diagnostic X-ray ... Opta[i] , ProGrade and PrimaryDiagnost[ii]. With new releases ... the U.S., and availability of all these solutions ... customers innovative solutions designed to meet the needs ...
Breaking Medicine Technology:Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 3Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 4Hovione Files its First Investigational New Drug Application With the FDA 2Philips expands global reach of diagnostic X-Ray solutions 2Philips expands global reach of diagnostic X-Ray solutions 3
... The automated solution for Western Blot analysis ... a fully automated Western Blot Analyzer for ... that reveal the presence of infectious diseases ... enables fast and accurate screening of allergies ...
... Advantages of using the Antigen-Antibody Pens-Using ... designed and developed specialized fountain pens, called ... deliver or write/mark the blotting membranes in ... specially formulated antigen-bonded colored dyes helps to ...
... of pure water, Complete, Compact Systems for ... compact S.D.S. Storage and Distribution Systems are ... of purified water produced by Elix or ... of stored water, provide effective protection against ...
... Liters of pure water, Complete, Compact Systems ... Water,Millipores compact S.D.S. Storage and Distribution Systems ... liters of purified water produced by Elix ... purity of stored water, provide effective protection ...
Medicine Products: