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New findings show Enbrel significantly reduced levels of C-reactive protein
Date:2/1/2008

r phototherapy.

What important information do I need to know about taking prescription Enbrel (etanercept)"

ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body's immune system makes called TNF. People with an immune disease, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and psoriasis, have too much TNF in their bodies. ENBREL can reduce the amount of TNF in the body to normal levels, helping to treat your disease. But, in doing so, ENBREL can also lower the ability of your immune system to fight infections.

All medicines have side effects, including ENBREL. Possible side effects of ENBREL include:

  • Serious infections

    • Many occurred in people prone to infection, such as those with advanced or poorly controlled diabetes

    • Some serious infections have been fatal
    • Rare cases of tuberculosis have occurred
  • What not to do
    • Do not start ENBREL if you have an infection, such as an open sore or the flu, or are allergic to ENBREL or its components

  • What to do
    • Tell your doctor if you are prone to infection or have had hepatitis B

    • Stop ENBREL if a serious infection occurs
    • Contact your doctor if you have questions about ENBREL or develop an infection
    • Tell your doctor if you have ever been treated for heart failure
    • Serious nervous system disorders, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes

    • Tell your doctor if you have ever had any of these disorders or if you develop them after starting ENBREL
  • Rare reports of serious blood disorders (some fatal)
    • Contact your doctor immediately if you develop symptoms, such as persistent fever, bruising, bleeding, or paleness
  • In medical studies of all TNF blockers, including ENBREL, a higher rate of lymph
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Contact: Sonia Fiorenza
fiorenza@amgen.com
805-447-1604
Porter Novelli
Source:Eurekalert

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