Navigation Links
New findings shed light on why smokers struggle to quit
Date:1/5/2009

DURHAM, NC Just seeing someone smoke can trigger smokers to abandon their nascent efforts to kick the habit, according to new research conducted at Duke University Medical Center.

Brain scans taken during normal smoking activity and 24 hours after quitting show there is a marked increase in a particular kind of brain activity when quitters see photographs of people smoking.

The study, which appears online in Psychopharmacology, sheds important light on why it's so hard for people to quit smoking, and why they relapse so quickly, explains Joseph McClernon, an associate professor in the department of psychiatry and behavioral sciences at Duke University Medical Center.

"Only five percent of unaided quit attempts result in successful abstinence," says McClernon. "Most smokers who try to quit return to smoking again. We are trying to understand how that process works in the brain, and this research brings us one step closer."

The Duke researchers used a brain-imaging tool called functional MRI to visualize changes in brain activity that occurs when smokers quit. The smokers were scanned once before quitting and again 24 hours after they quit. Each time they were scanned while being shown photographs of people smoking.

"Quitting smoking dramatically increased brain activity in response to seeing the smoking cues," says McClernon, "which seems to indicate that quitting smoking is actually sensitizing the brain to these smoking cues."

Even more surprising, he adds, is the area of the brain that was activated by the cues. "We saw activation in the dorsal striatum, an area involved in learning habits or things we do by rote, like riding a bike or brushing our teeth. Our research shows us that when smokers encounter these cues after quitting, it activates the area of the brain responsible for automatic responses. That means quitting smoking may not be a matter of conscious control. So, if we're really going to help people quit, this emphasizes the need to do more than tell people to resist temptation. We also have to help them break that habitual response."

New treatment options at Duke are aiming to do just that. One area of research is focusing on the use of a nicotine patch prior to quitting smoking.

In previously published research, Jed Rose, Director of the Duke Center for Nicotine and Smoking Cessation Research and co-author of this paper as well, showed that wearing the patch and smoking a cigarette with no nicotine proved successful at breaking the learned behavior. "The smoking behavior is not reinforced because the act of smoking is not leading them to get the nicotine," Rose said. "Doing this before people actually quit helps them break the habit so they start smoking less. We're seeing people quit longer this way."


'/>"/>

Contact: Debbe Geiger
Debbe.Geiger@duke.edu
919-660-9461
Duke University Medical Center
Source:Eurekalert

Related medicine news :

1. Bionovo to Present Recent Findings of BN108, its Anticancer Agent, at the 31st Annual San Antonio Breast Cancer Symposium
2. Breast cancer in men: Mammography and sonography findings
3. Initial Survey Findings on Diabetes Awareness Released by PatientAssistance.com
4. Best Practice Database Provides Key Findings for Biopharma Product Launch Evaluation
5. Tibotec presents interim findings for TMC435, an investigational genotype 1 hepatitis C treatment
6. NABP Findings Underscore Dangers of Purchasing Prescription Medicine Online and From Foreign Sources
7. New National Public Opinion Survey Reveals Important Findings on Oral Health Care Perceptions
8. New findings may improve treatment of inherited breast cancer
9. Curemark CEO Presents Autism Findings at Prestigious Neurobiology Conference at Oxford
10. Endoscopic ultrasound highly accurate in evaluating ambiguous radiographic findings of the pancreas
11. Positive Findings Published on Emergent Technology for Treating Chronic Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/6/2016)... ... December 06, 2016 , ... TopConsumerReviews.com recently gave a best-in-class 5 star rating ... Scooters give freedom to people who need help getting around. For some, advancing age ... long period of rehabilitation after an illness or accident. There is a wide variety ...
(Date:12/6/2016)... ... December 06, 2016 , ... ... magazine’s 2017 Training Top 125 for their industry leading training methods that engage ... recognizes USA as among the global elite in employer-sponsored training and development programs. ...
(Date:12/5/2016)... ... 2016 , ... Edward Buckingham MD , and the ... the newest Sciton laser in January 2017. The Halo is the first and ... wavelengths for exceptional results. Outperforming more traditional lasers, the innovative Halo automatically customizes ...
(Date:12/5/2016)... (PRWEB) , ... December 05, 2016 , ... ... announced it has been featured in SuperbCrew magazine, a leading online tech news ... world. This interview, now featured on SuperbCrew.com, explores the state of enterprise mobility ...
(Date:12/5/2016)... Novato, CA (PRWEB) , ... December 05, 2016 ... ... company, has extended its partnership with leading global lifestyle design firm kathy ireland® ... , Worldwise® and kathy ireland® Worldwide entered into an exclusive licensing agreement three ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... , Dec. 5, 2016 Sanovas, Inc., ... accelerator, announced today the launch of its wholly owned subsidiary, ... Logo - http://photos.prnewswire.com/prnh/20161202/445250LOGO   Logo - http://photos.prnewswire.com/prnh/20161202/445251LOGO   ... ... There are ...
(Date:12/5/2016)... -- Wellbridge Health and Gateway Health proudly announce a dynamic collaboration ... Medicaid plan members with specific high risk needs. ... this group of consumers, Wellbridge combines technology and population expertise ... into members, daily behaviors and lifestyle. ... , , ...
(Date:12/5/2016)... 5, 2016  Recently Zymo Research announced an ... known as Horvath,s Clock. Based on this technology, ... service to academic and biopharma scientific researchers to ... other than sperm. The service quantifies ... age versus chronological age following drug treatments and ...
Breaking Medicine Technology: