Navigation Links
New findings on the formation of body pigment
Date:10/16/2009

The skin's pigment cells can be formed from completely different cells than has hitherto been thought, a new study from the Swedish medical university Karolinska Institutet shows. The results, which are published in the journal Cell, also mean the discovery of a new kind of stem cell.

The body's pigment gives essential protection against UV radiation. It is made up of a substance called melanin, which is produced by pigment cells in the skin called melanocytes. According to the established theory of body pigmentation, these melanocytes bud off from the spinal cord at an early foetal stage and then migrate to the skin where they remain for the rest of their lives.

Scientists at Karolinska Institutet in Stockholm have now shown that most melanocytes actually appear later on in foetal development from an immature cell type that exists in the skin's nerve fibres. These cells, called Schwann cell precursors (SCPs), can also be found in adults. In addition to this, the scientists have demonstrated how neuronal damage in adults can excite the maturation of melanocytes to form hyperpigmentation around the affected nerves.

"Our findings can provide new knowledge of how changes in skin pigmentation occur, not least of the links that have been observed between neurological disease and changes in pigmentation," says Professor Patrik Ernfors, who led the study.

Their results also shed new light on SCP cells, which were previously seen as an immature form of supportive cells the nervous system. The researchers describe how a change in cell signalling can make the SCP cells in the skin develop into pigment cells instead, and argue that SCP cells are really a kind of stem cell.

"This can help science to understand the development of diseases such as melanoma," says Professor Ernfors. "We've always believed that it develops from melanocytes, but maybe it actually originates in the SCP cells."


'/>"/>

Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Source:Eurekalert

Page: 1

Related medicine news :

1. Many Parents Share Genetic Test Findings With Kids
2. New Alzheimers findings: High stress and genetic risk factor lead to increased memory decline
3. Scientists, physicians present latest findings in personalized cancer treatment and prevention
4. Health psychologists discuss latest research findings
5. Incidental findings found when radiologists take a broader look at renal MRA
6. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
7. The Organic Trade Association Hails Preliminary Research Findings Showing Nutritional Benefits of Organic Products
8. Key findings for all veterans seen in depression and suicide study
9. Video: BSP Pharma Inc. Announces Groundbreaking Findings from The Australian Centre for Complementary Medicine Education and Research Joint Health Clinical Study
10. 2007 Life Sciences Compensation Findings Disclosed www.compstudy.com
11. Chemoprevention, naturally: Findings on plant-derived cancer medicines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, ... ... School of Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, ... professionals on guideline updates for the primary prevention of cardiovascular diseases during ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... ... October 12, 2017 , ... The ... demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, ... to meet the highest standard. , These products are also: Gluten Free, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
(Date:9/18/2017)... , Sept. 18, 2017  PMD Healthcare of ... Pharmacy of Kalamazoo, Mich. , have ... service that expedites and streamlines patient and provider access ... 2.0, and wellness management services.  ... used to measure lung function for a variety of ...
(Date:9/13/2017)... , Sept. 13, 2017   OrthoAtlanta has been ... Atlanta Football Host Committee (AFHC) for the 2018 College Football ... 8, 2018, at Mercedes-Benz Stadium in Atlanta, Georgia ... the AFHC "I,m In" campaign, participating in many activities leading ... ...
Breaking Medicine Technology: