Navigation Links
New evidence that 'gout' strongly runs in the family
Date:12/2/2013

It's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed that 'gout' strongly runs in families.

Researchers in the Division of Rheumatology, Orthopaedics and Dermatology studied the whole population of Taiwan (23 million) where gout is most prevalent in the world. The findings have just been published in the leading rheumatology journal, Annals of the Rheumatic Diseases.

By examining 4.2 million identifiable families, the scientists found compelling evidence that the disease clusters in families, with increased risks for people with first and second degree relatives suffering from gout.

Gout is a kind of inflammatory arthritis, with sudden onset of acute pain, redness and swelling in peripheral joints, most commonly the joint in the big toe. It is caused by the deposition of monosodium urate crystals, which is related to high uric acid in the blood. The resulting acute arthritis and lumps around the joint cause disability due to pain and loss of joint function.

There is also increasing evidence that gout is not only a disease of joints but also is associated with major cardiovascular (heart attack, stroke) and renal diseases (kidney failure).

Previous studies had suggested that gout often clusters within families, which is indirect evidence for a role of genetic factors in causation. However, one recent classic twin study paradoxically found strong heritability for high uric acid but no evidence for heritability in gout.

Lead researcher on the project, Dr Chang Fu Kuo, said: "Our results confirm the clinical belief that gout strongly clusters within families. In Taiwan the risk of an individual with any first-degree relative suffering from gout is approximately twice that of the normal population.

"The risk increases with the number of the first-
'/>"/>

Contact: Emma Rayner
emma.rayner@nottingham.ac.uk
44-011-595-15793
University of Nottingham
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers find evidence of banned antibiotics in poultry products
2. Report says new evidence could tip the balance in aspirin cancer prevention care
3. More Evidence Bilingualism Aids Thinking Skills
4. Novel biomarkers reveal evidence of radiation exposure
5. Antiretroviral treatment for preventing HIV infection: an evidence review for physicians
6. WSU study finds overwhelming evidence of hidden heart disease in hypertensive African-Americans
7. Study shows no evidence medical marijuana increases teen drug use
8. Study of Retired NFL Players Finds Evidence of Brain Damage
9. New evidence for link between obesity and circle of friends
10. Cochrane finds no reliable evidence on effectiveness of electric fans in heatwaves
11. Study Gives First Evidence That Adult Human Lungs Can Regrow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... (PRWEB) July 12, 2014 As reported in ... Institute of Standards and Technology), the June 25th, 2014 Supreme ... electronic discovery world. It was also met with ... depending on whether it was seen from an individual privacy ... much is fact, there is now precedent which will require ...
(Date:7/12/2014)... A recent article released by Seattle's well known plastic ... those seeking cosmetic surgical procedures in summer months . ... heat begins to enliven the rainy Pacific Northwest, many people ... they didn’t work out as much during the winter as ... surge of people eager to look their best for their ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Restore My ... Sen and Samantha Pearson, a couple boasting very impressive ... launch Restore My Vision Today as a way to ... ophthalmologists have become in their respective patients’ treatments ... privy to a “secret” trove of pertinent information relevant ...
(Date:7/12/2014)... 2014 The largest pure occupational medicine ... to announce that it will be opening its fifth ... will join four Atlanta-based Nova Medical Centers’ locations. The ... Deans Bridge Road, and will be open from 8:30 ... “With Nova’s treatment philosophy of rapid return-to-work and decreased ...
(Date:7/11/2014)... DressyQuinceanera.com, a well-known wedding dress manufacturer and retailer, has ... online category. Furthermore, the firm has announced that all ... to 62% off. , The brand new Quinceanera Dama ... quality and style. All items in the new collection ... the company’s other items: lace evening dresses, short bridesmaid ...
Breaking Medicine News(10 mins):Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 2Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 3Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 4Health News:Mobile Device Forensics Guidelines Play Key Role in Supreme Court’s Smartphone Evidence Warrant Decision 5Health News:Best Summer Cosmetic Surgeries Revealed in Article By Seattle Plastic Surgeon 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 3Health News:Nova Medical Centers To Open New Facility in Augusta, Georgia 2Health News:DressyQuinceanera.com: Beautiful Quinceanera Dama Dresses At Low Prices 2
... women's infant mortality rates in Florida is widening, Florida ... on Wednesday, the Tallahassee Democrat reports. ... Health Service division, the state's racial gap in infant ... are twice as likely to have premature babies in ...
... Japanese firm announced this week that it has developed ... significantly improve// the efficacy of chemotherapy drugs and reduce ... (NDT), the US subsidiary of Nitto Denko Corporation, says ... and biocompatible polymer material which can be loaded with ...
... The African Malaria Network Trust (AMANET) has received a ... & Melinda Gates// Foundation. ,According to the ... the four-year grant is aimed at strengthening institutional capacity ... ,It also aims at fostering and promoting discussion, ...
... drug Avastin has been tested for the first time against ... ,Duke University researchers used Avastin, known chemically as bevacizumab, ... recurrent brain tumors called gliomas. Good news -- the two ... any other therapy. ,Gliomas are mostly incurable in ...
... confirmed the presence of bird flu in their county. This ... ministry. ,The lethal H5N1 virus was found in ... was suspected, later it was diagnosed as the case of ... necessary precautions are being followed. ,Culling of birds ...
... stated a tobacco industry memo from 1969. For half a ... smoking and cancer. Now, with that effort long since failed, ... again attempting to manufacture doubt. ,"The tobacco industry ... saying that everyone knew but no one had proof," said ...
Cached Medicine News:Health News:New Cost-cutting Cancer Drug Delivery System 2Health News:New Cost-cutting Cancer Drug Delivery System 3Health News:Tobacco Companies Obstructed Science 2Health News:Tobacco Companies Obstructed Science 3
(Date:7/10/2014)... 10, 2014  RESMED INC. (NYSE: RMD ) ... fiscal year ended June 30, 2014 results on Thursday, July ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:7/10/2014)... 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... completed the sale to Galderma of all rights to ... by Valeant for $1.4 billion in cash, pursuant to ... completed its acquisition of Galderma. "We ... to a company that is firmly committed to the ...
(Date:7/10/2014)... Israel , July 10, 2014   ... Diabetes Management Solution, today announced the appointment of ... independent member of its Board of Directors. ... legal and business experience to LabStyle as an ... and legal and corporate governance expert. He currently ...
Breaking Medicine Technology:ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4
... Valeritas, Inc., a medical technology ... innovative drug delivery solutions, announced today that the ... company,s V-Go Disposable Insulin Delivery Device for use ... delivery of insulin in preset basal rates and ...
... Dehaier Medical Systems Ltd. (Nasdaq: DHRM ... in the development, assembly, marketing and sale of ... today announced that management will present at the ... (Logo: http://photos.prnewswire.com/prnh/20100422/CNTH001LOGO ) Rodman & ...
Cached Medicine Technology:Valeritas Receives FDA 510(k) Clearance for the V-Go™ Disposable Insulin Delivery Device for Use with NovoLog® 2Valeritas Receives FDA 510(k) Clearance for the V-Go™ Disposable Insulin Delivery Device for Use with NovoLog® 3Dehaier Medical Announces March Investor Presentations 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: