Navigation Links
New evidence for epigenetic effects of diet on healthy aging
Date:12/6/2012

New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by ageing but are also affected by what we eat.

The study showed that whilst age had the biggest effects on these molecular changes, selenium and vitamin D status reduced the accumulation of epigenetic changes, and high blood folate and obesity increased them. These findings support the idea that healthy ageing is affected by what we eat.

Researchers from the Institute of Food Research led by Dr Nigel Belshaw, working with Prof John Mathers and colleagues from Newcastle University, examined the cells lining the gut wall from volunteers attending colonoscopy clinic. The Institute of Food Research is strategically funded the Biotechnology and Biological Sciences Research Council and this study was also funded by the Food Standards Agency.

The study volunteers were free from cancer or inflammatory bowel disease and consumed their usual diet without any supplements. The researchers looked for specific epigenetic modifications of the volunteers' genes that have been associated with the earliest signs of the onset of bowel cancer an age-related disease. These epigenetic marks, known as DNA methylation, do not alter the genetic code but affect whether the genes are turned on or off. These methylation marks are transmitted when cells divide, and some have been associated with the development of cancer. The investigators studied the relationship between the occurrence of these epigenetic marks at genes known to be affected in cancer, and factors including the volunteers' age, sex, body size and the levels of some nutrients in the volunteers' blood. The biggest influence on gene methylation was age. This fits with the fact that the biggest risk factor for bowel cancer is age, with risk increasing exponentially over 50 years old.

The findings, published in the journal Aging Cell, showed that men tended to have a highe
'/>"/>

Contact: Andrew Chapple
andrew.chapple@ifr.ac.uk
44-016-032-51490
Norwich BioScience Institutes
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Largest coronary artery disease study shows evidence of link between inflammation and heart disease
2. McKinney Orthodontics Educates on New Evidence that Crooked Teeth are Genetic
3. Researchers identify physiological evidence of chemo brain
4. Researchers find evidence that brain compensates after traumatic injury
5. Merck and Regenstrief Institute establish evidence-based care collaboration
6. More Evidence That Truvada Can Help Prevent HIV
7. More Evidence Acupuncture Can Ease Chronic Pain
8. Researchers find first evidence for a genetic cause for Barretts esophagus
9. Little evidence of health benefits from organic foods, Stanford study finds
10. Review finds some evidence for chemo brain in breast cancer survivors, Moffitt Cancer Center says
11. Nurse leader resistance perceived as a barrier to high-quality, evidence-based patient care
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New evidence for epigenetic effects of diet on healthy aging
(Date:1/22/2015)... The U.S. Pharmacopeial Convention is pleased to ... Pharmacy Services at North Carolina State’s College of Veterinary ... Beal Award for Distinguished Volunteer Service—the organization’s highest award. ... contributions of volunteer experts to direct its work to ...
(Date:1/22/2015)... Chemo Duck Program is pleased to announce the release of the ... with cancer. The Chemo Duck App, available on iTunes for use ... to help children of all ages living with cancer adjust to ... entertained, educated and at ease while waiting for clinic visits or ...
(Date:1/22/2015)... EAGAN, Minn. (PRWEB) January 22, 2015 Blue ... discover those Minnesotans who exemplify what it means to “Live ... a chance for people to share their stories about how ... adversity or simply inspired others by living in the moment. ...
(Date:1/22/2015)... Thousand of GranuFlo lawsuits ( http://www.granuflolawsuit2014.com/ ... GranuFlo and NaturaLyte dialysis concentrates continue to move forward ... Court, District of Massachusetts, Bernstein Liebhard LLP reports. According ... remanded a case filed by the state of Louisiana ...
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
Breaking Medicine News(10 mins):Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 2Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 3Health News:Gigi Davidson, Pioneer in Veterinary Pharmacy and Leader in Pharmacy Compounding, honored with USP’s Beal Award for Dedication to Public Health 4Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3
... ... distributors for growing national meal company Diet-to-Go , ... (PRWEB) February 9, 2010 -- Diet-to-Go, a national leader ... the Philadelphia area by adding a pair of prestigious new Partners-in-Health, 12th Street Gym ...
... ... technology: simplicity, mobility, and automation. When the iPad was announced on January 27th, we ... we,ve dedicated more than a week of intensive software development to it, it,s clear that ... application to the next level. , ...
... ... on his laptop computer when his rig hit a disabled car and killed the driver. ... New York, NY (PRWEB) February 9, 2010 ... his laptop computer, according to New York state police. His truck crashed into her disabled car ...
... of most electronic media is not associated with headaches, at ... olds, published in the open access journal BMC Neurology ... mobile phones or television and the occurrence of headaches or ... every day was associated with a pounding head. Astrid ...
... , LITTLE FALLS, N.J. ... reading to stay informed about key developments? MedPage Today publishes the Most ... Past Week will be published Every Monday and will be available by ... Reviewed , ICU Catheter Infections Can Be Virtually ...
... , PORT-AU-PRINCE, Haiti , Feb. 8 ... face more than just staggering physical needs such as food and shelter, ... humanitarian agency spoke to had lost loved ones--including friends, extended family or ... normal routines in order to recover, the Christian aid group ...
Cached Medicine News:Health News:Diet-to-Go Welcomes 2 Key Philadelphia Fitness Centers as Partners-in-Health 2Health News:Diet-to-Go Welcomes 2 Key Philadelphia Fitness Centers as Partners-in-Health 3Health News:The Case for the iPad: Mobile Charge Capture for Physicians 2Health News:The Case for the iPad: Mobile Charge Capture for Physicians 3Health News:The Case for the iPad: Mobile Charge Capture for Physicians 4Health News:New York Truck Driver Watching Porn Kills Mother, Appalls Personal Injury Lawyers Such As David Perecman 2Health News:New York Truck Driver Watching Porn Kills Mother, Appalls Personal Injury Lawyers Such As David Perecman 3Health News:MedPage Today(R) 'What Your Physicians Are Reading' 2Health News:MedPage Today(R) 'What Your Physicians Are Reading' 3Health News:Haiti, a Nation in Mourning 2Health News:Haiti, a Nation in Mourning 3Health News:Haiti, a Nation in Mourning 4
(Date:1/23/2015)... N.Y. , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. ... its Phase I trial of Lixte,s lead compound, LB‑100, is ... John S. Kovach , M.D., the founder ... planned to be completed at a single site. Accrual of ...
(Date:1/23/2015)... 2015  CytoSorbents Corporation (NASDAQ CM: CTSO), a critical ... adsorber to reduce deadly inflammation in critically-ill and ... net of transaction costs, in non-dilutive funding as ... Certificate Transfer Program sponsored by the New Jersey ...
(Date:1/23/2015)... BOSTON , January 23, 2015 Heptares ... is delighted to announce that the Malcolm Campbell ... Congreve (Vice President of Chemistry), Fiona Marshall ... (Chief Executive Officer and co-founder) for the seminal contributions to ...
Breaking Medicine Technology:Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4
... It's easy on delicate ... design and hydrophilic coating provide ... lubricating gel. It's easy to ... the catheter with its own ...
... delicate urethral tissues. The gentle, ... provide nearly friction-free movement, without ... to maintain sterility. You simply ... own sterile water, avoiding contamination ...
The latex-free, PVC-free Antibacterial Hydro Personal catheter combines two remarkable innovations into one exclusive catheter that delivers an antibacterial agent while providing the virtually frict...
... Rochester Medical's line ... the intermittent catheters you ... All four product configurations ... and antibacterial hydro - ...
Medicine Products: