Navigation Links
New evidence for epigenetic effects of diet on healthy aging
Date:12/6/2012

New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by ageing but are also affected by what we eat.

The study showed that whilst age had the biggest effects on these molecular changes, selenium and vitamin D status reduced the accumulation of epigenetic changes, and high blood folate and obesity increased them. These findings support the idea that healthy ageing is affected by what we eat.

Researchers from the Institute of Food Research led by Dr Nigel Belshaw, working with Prof John Mathers and colleagues from Newcastle University, examined the cells lining the gut wall from volunteers attending colonoscopy clinic. The Institute of Food Research is strategically funded the Biotechnology and Biological Sciences Research Council and this study was also funded by the Food Standards Agency.

The study volunteers were free from cancer or inflammatory bowel disease and consumed their usual diet without any supplements. The researchers looked for specific epigenetic modifications of the volunteers' genes that have been associated with the earliest signs of the onset of bowel cancer an age-related disease. These epigenetic marks, known as DNA methylation, do not alter the genetic code but affect whether the genes are turned on or off. These methylation marks are transmitted when cells divide, and some have been associated with the development of cancer. The investigators studied the relationship between the occurrence of these epigenetic marks at genes known to be affected in cancer, and factors including the volunteers' age, sex, body size and the levels of some nutrients in the volunteers' blood. The biggest influence on gene methylation was age. This fits with the fact that the biggest risk factor for bowel cancer is age, with risk increasing exponentially over 50 years old.

The findings, published in the journal Aging Cell, showed that men tended to have a highe
'/>"/>

Contact: Andrew Chapple
andrew.chapple@ifr.ac.uk
44-016-032-51490
Norwich BioScience Institutes
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Largest coronary artery disease study shows evidence of link between inflammation and heart disease
2. McKinney Orthodontics Educates on New Evidence that Crooked Teeth are Genetic
3. Researchers identify physiological evidence of chemo brain
4. Researchers find evidence that brain compensates after traumatic injury
5. Merck and Regenstrief Institute establish evidence-based care collaboration
6. More Evidence That Truvada Can Help Prevent HIV
7. More Evidence Acupuncture Can Ease Chronic Pain
8. Researchers find first evidence for a genetic cause for Barretts esophagus
9. Little evidence of health benefits from organic foods, Stanford study finds
10. Review finds some evidence for chemo brain in breast cancer survivors, Moffitt Cancer Center says
11. Nurse leader resistance perceived as a barrier to high-quality, evidence-based patient care
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New evidence for epigenetic effects of diet on healthy aging
(Date:10/22/2014)... October 22, 2014 Best Cheap Hosting ... the world. The site has recently announced that iPower ... supplier for people from around the world. , “iPower ... operation today and is providing various kinds of useful ... company insists on offering excellent customer service and a ...
(Date:10/22/2014)... Mission Viejo, CA (PRWEB) October 22, 2014 ... that Jay Cormier, Sr. Vice President of Sales, will ... at the upcoming Meetings Technology Expo on October 28, ... will also be hosting a booth as well as ... on how Lintelus Meeting can create a more engaging ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. ... fertilization (IVF) are only about half as likely as white ... new research indicates, and the racial disparity persists even when ... percent of white patients became pregnant after IVF, compared to ... 4,000 IVF cycles over two years to tease out the ...
(Date:10/22/2014)... Oct. 21, 2014 (HealthDay News) -- Measures taken by ... in Ebola-ravaged Liberia may have limited the spread of ... report. The Firestone Natural Rubber Co. provides health ... residents of nearby densely populated communities. Between Aug. ... suspected Ebola cases among those 80,000 people. That incidence ...
(Date:10/20/2014)... 2014 With a mere 19 days ... made a brief fundraising stop at the  Law ... Fresh from a debate last night with his opponent ... for the first seven minutes because Crist had an ... the incident in one word: "weird." , Before touching ...
Breaking Medicine News(10 mins):Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3
... , FRIDAY, March 11 (HealthDay News) -- It may be ... environmental health concern in the United States, much less one ... country. But a radioactive gas known as radon is ... according to the U.S. National Cancer Institute. "It,s the ...
... carcinoma in situDCISwho later develop invasive breast cancer in ... from breast cancer than those who do not develop ... 11 in the Journal of the National Cancer ... have compared breast conserving surgery (lumpectomy) to mastectomy and ...
... , FRIDAY, March 11 (HealthDay News) -- Text ... are tailored to the individual, according to researchers who conducted ... functional MRI was used to pinpoint the brain regions most ... "a war that consists of a series of momentary self-control ...
... March 11 (HealthDay News) -- Taking aspirin to protect ... people at increased risk for the disease due to ... according to a new study. Previous research has ... anti-inflammatory drugs (NSAIDs) have a reduced risk of colorectal ...
... Dr. Bang H. Hoang and colleagues have been presented the ... advancing the understanding of how bone cancer spreads. The ... the recent American Academy of Orthopaedic Surgeons annual meeting. Since ... honors bestowed by the AAOS and the Orthopaedic Research Society. ...
... , FRIDAY, March 11 (HealthDay News) -- Watching your team ... score can be thrilling, but there may be a drawback: ... study has found that traffic deaths at the game site ... the "nail-biter" game is over. Researchers at North Carolina ...
Cached Medicine News:Health News:Invisible and Odorless, Radon Poses Risks to Lungs 2Health News:Invisible and Odorless, Radon Poses Risks to Lungs 3Health News:Invisible and Odorless, Radon Poses Risks to Lungs 4Health News:DCIS patients who get invasive breast cancer have higher mortality 2Health News:Text Messages May Help Smokers Kick the Addiction, Small Study Finds 2Health News:Aspirin May Protect Against Colorectal Cancer -- But Only in Certain People 2Health News:Fans of Winning Teams Linked to Fatal Crashes 2
(Date:10/22/2014)... Oct. 22, 2014  Recently published clinical studies of ... already substantial database of evidence. This data has led ... Stretta therapy for sufferers of refractory GERD. ... supporting Stretta therapy as a safe and effective ... Stretta therapy available to nearly 50 million Americans. The ...
(Date:10/22/2014)... SHANGHAI , Oct. 22, 2014   ... and WuXi PharmaTech (Cayman) Inc. (NYSE: WX ... comprehensive genomic profiling to biopharmaceutical companies conducting clinical trials ... Under the terms of the collaboration, Foundation Medicine will ... of Foundation Medicine,s FoundationOne® assay at the WuXi Genome ...
(Date:10/20/2014)... 20 de octubre de 2014  PneumRx, Inc. ... de la pulmonología intervencional, anunció hoy la conclusión ... 3 meses antes de lo programado. El Estudio Clínico ... dispositivo de investigación (IDE) aprobada por la FDA ... de espiral de reducción de volumen pulmonar PneumRx ...
Breaking Medicine Technology:Recent Clinical Study Data Confirms Efficacy of Stretta Therapy - Spurs Additional Insurance Coverage and Financing Round 2Foundation Medicine and WuXi PharmaTech Announce Strategic Collaboration to Offer Best-in-Class Comprehensive Genomic Profiling in China 2Foundation Medicine and WuXi PharmaTech Announce Strategic Collaboration to Offer Best-in-Class Comprehensive Genomic Profiling in China 3Foundation Medicine and WuXi PharmaTech Announce Strategic Collaboration to Offer Best-in-Class Comprehensive Genomic Profiling in China 4Foundation Medicine and WuXi PharmaTech Announce Strategic Collaboration to Offer Best-in-Class Comprehensive Genomic Profiling in China 5PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3
... Kendall provides hospitals and alternate ... of tracheostomy care trays which offer ... infection control. Designed with the guidance ... total-care trays provide exactly what is ...
... Kendall provides hospitals and alternate care ... tracheostomy care trays which offer the ... control. Designed with the guidance of ... trays provide exactly what is required ...
... Kendall provides hospitals and alternate care ... tracheostomy care trays which offer the ... control. Designed with the guidance of ... trays provide exactly what is required ...
Indications For Usage: ,Bypass upper airway obstructions, provide long term ventilation, support and/or manage tracheal/bronchial secretions....
Medicine Products: