Navigation Links
New electrically-conductive polymer nanoparticles can generate heat to kill colorectal cancer cells
Date:11/20/2012

WINSTON-SALEM, N.C., Nov. 20, 2012 Researchers at Wake Forest Baptist Medical Center have modified electrically-conductive polymers, commonly used in solar energy applications, to develop revolutionary polymer nanoparticles (PNs) for a medical application. When the nanoparticles are exposed to infrared light, they generate heat that can be used to kill colorectal cancer cells.

The study was directed by Assistant Professor of Plastic and Reconstructive Surgery, Nicole H. Levi-Polyachenko, Ph.D., and done in collaboration with colleagues at the Center for Nanotechnology and Molecular Materials at Wake Forest University. This study was recently published online, ahead of print, in the journal, Macromolecular Bioscience (DOI: 10.1002/mabi.201200241).

Levi-Polyachenko and her team discovered a novel formulation that gives the polymers two important capabilities for medical applications: the polymers can be made into nanoparticles that are easily dispersed in water and generate a lot of heat when exposed to infrared light.

Results of this study showed that when colorectal cancer cells incubated with the PNs were exposed to five minutes of infrared light, the treatment killed up to 95 percent of cells. "The results of this study demonstrate how new medical advancements are being developed from materials science research," said Levi-Polyachenko.

The team made polymer nanoparticles and showed that they could undergo repeated cycles of heating and cooling without affecting their heating ability. This offers advantages over metal nanoparticles, which can melt during photothermal treatments, leading to a loss of heating efficiency. This also allows for subsequent treatments to target cells that are resistant to heat-induced killing.

A challenge with other electrically-conductive polymers that have recently been explored for photothermal therapy is that these other polymers absorb across a wide range of infrared
'/>"/>

Contact: Paula Faria
pfaria@wakehealth.edu
336-716-1279
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Singular polymer, multiple functions
2. Applied nanobiomedicine: Exploiting nanoparticles to hunt for hidden cancer cells
3. Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment
4. Researchers find gold nanoparticles capable of unzipping DNA
5. New nanoparticles shrink tumors in mice
6. UCSB scientists examine effects of manufactured nanoparticles on soybean crops
7. Improved nanoparticles deliver drugs into brain
8. Nanoparticles detect biochemistry of inflammation
9. UGA researchers boost efficacy of drugs by using nanoparticles to target powerhouse of cells
10. New technique predictably generates complex, wavy shapes
11. Abnormal gene product associated with prostate cancer generated by unusual mechanism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... understanding of how living things function comes from knowledge ... of life, the receptors that are docking stations for ... and RNA that carry genetic blueprints for building cellular ... access to these structural details, a new grant just ... the U.S. Department of Energy (DOE) will fund the ...
(Date:9/23/2014)... New York, N.Y. (PRWEB) September 23, 2014 ... supplement to join the Royal Sport LTD family of ... 100 calories and 20g of pure Whey protein without ... , This ‘Ultra Clean’ protein is available on shelves ... Royal Sport LTD website—where the brand is offering a ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 ADOMANI, Inc. ... serving as President and CEO. He is a 13-year veteran ... former President and CEO of A-Z Bus Sales of Colton, ... of their success, growing their top line revenues, profit and ... their gas or diesel to all-electric or plug-in hybrid ...
(Date:9/23/2014)... 2014 Airbus Helicopters Inc. (AHI) is ... as the 2014 Vision Zero Aviation Safety Award ... database, a free flight safety service the company provides ... - Air Medical Specialist for Airbus Helicopters Inc., presented ... check during the Air Medical Transport Conference Annual Community ...
(Date:9/23/2014)... special issue of the European Journal of Cancer ... research presented during the 1st EORTC Cancer Survivorship Summit ... diagnosis, targeted therapeutics, and more personalized multimodal treatments has ... to a large and rapidly increasing number of cancer ... confronted with a broad spectrum of late adverse treatment ...
Breaking Medicine News(10 mins):Health News:New NIH/DOE grant for life science studies at NSLS-II 2Health News:New NIH/DOE grant for life science studies at NSLS-II 3Health News:Sports Nutrition Brand, Royal Sport LTD, Introduces 'Clean,' Gluten Free Protein Supplement, Royal Sport Ultra Clean 100™ 2Health News:ADOMANI Announces Jim Reynolds to Take Over as President and CEO 2Health News:Protean wins Airbus Helicopters Vision Zero Aviation Safety Award 2Health News:Protean wins Airbus Helicopters Vision Zero Aviation Safety Award 3Health News:Protean wins Airbus Helicopters Vision Zero Aviation Safety Award 4
... a significantly enhanced quality of life in old age ... less afraid of death than their less religious peers ... professor of sociology at the University of New Hampshire. ... her collaborator, Paul Wink, professor of psychology at Wellesley ...
... for chronic obstructive pulmonary disease (COPD), can be ... new study. The research, presented at CHEST 2006 ... of the American College of Chest Physicians (ACCP), ... a large proportion of subjects with significant impairment. ...
... years will soon be assessed by a new random-dot stereotest ... article published in the November 2006 // issue of Investigative ... children, 38 with various visual impairments and 18 with normal ... alone with their heads stabilized by a chin and front ...
... law which makes possession of child pornography material a federal ... is a pedophile or become one based on the child ... number of cases are going to court and attorneys are ... person has child porn on their computer," said Dr. Humberto ...
... diabetes in middle age could face more complications later in ... new study.// ,Elizabeth Selvin of the Johns Hopkins Bloomberg ... than 2,800 people aged 65 and above with diabetes who ... the online edition of health Magazine WebMD. ,The ...
... Researchers from the Autonomous University of Tamaulipas are putting teeth ... of pacifiers by babies in their first year of birth, ... alignment in complete disarray. ,Researchers are armed to ... children between the ages of 4 and 5 who were ...
Cached Medicine News:Health News:Religious Adults Have a Higher Quality of Life than Their Peers 2Health News:Large Community Spirometry Screening Proves Successful 2Health News:Does Child pornography lead to Child abuse? 2Health News:Does Child pornography lead to Child abuse? 3
(Date:9/23/2014)... Pa. , Sept. 23, 2014 The Pennsylvania ... drugs Sat., Sept. 27, as part of National Prescription ... no questions asked. Take-Back Day is a ... Enforcement Administration (DEA), aimed at encouraging the public to ... are prone to abuse and theft. From ...
(Date:9/23/2014)... , Sept. 23, 2014 Galmed Pharmaceuticals ... clinical-stage biopharmaceutical company focused on the development and ... treatment of liver diseases and cholesterol gallstones, announced ... or the FDA, approved its request for Fast ... the treatment of Non-Alcoholic Steato-Hepatitis, or NASH.  ...
(Date:9/23/2014)... -- Vesselon, Inc. today announced the appointment of Jurgen Raths, ... 2014. Dr. Raths, appointment follows Vesselon,s engagement with Spencer ... a private preferred Series A round to facilitate development ... "Jurgen,s deep experience across multiple functional areas of medical ... as we develop our device that can be compared ...
Breaking Medicine Technology:Galmed Pharmaceuticals Announces U.S. FDA Approval of Fast Track Designation of Aramchol for the Treatment of NASH 2Galmed Pharmaceuticals Announces U.S. FDA Approval of Fast Track Designation of Aramchol for the Treatment of NASH 3Vesselon Announces Jurgen Raths, MD to Serve on Board of Directors 2Vesselon Announces Jurgen Raths, MD to Serve on Board of Directors 3
... 2011 Express Scripts (Nasdaq: ESRX ), one ... announced today its intention to release its third quarter earnings ... will hold its quarterly conference call to discuss third quarter ... Time (8:30 a.m. Central Time). This call is ...
... U.S. Food and Drug Administration has issued a proposed ... classification for external pacemaker pulse generators from Class III ... http://photos.prnewswire.com/prnh/20090824/FDALOGO ) External pacemaker pulse generators are ... permanent pacemaker can be implanted. They are also used ...
Cached Medicine Technology:FDA Proposes Lower Risk Classification, Special Controls for External Pacemakers 2FDA Proposes Lower Risk Classification, Special Controls for External Pacemakers 3
DS 7600 Central Station...
... MedSystem III DLE (Drug List Editor) Multi-Channel ... drug infusion technology. The instrument combines three ... clinical versatility in an unparalleled small size. ... MedSystem III Infusion System simplifies the delivery ...
... Freedom Chart Manager provides powerful workflow tools ... management, integrated transcription services, and customized flow ... that eliminates the need for paper charts. ... of a paperless office now and can ...
... ChartingPlus proves itself to over 2,000 ... Designed with the user in mind, ChartingPlus ... powerful and dynamic features to improve documentation ... practice. Our medical content is ...
Medicine Products: