Navigation Links
New drug found effective against rare form of basal cell skin cancer
Date:6/6/2012

New York, NY (June 6, 2012) A clinical study has demonstrated that a new drug, a targeted molecular therapy called vismodegib (trade name Erivedge), can dramatically shrink basal cell skin cancers and prevent the formation of new ones, in patients with basal cell nevus syndrome (BCNS). This rare genetic condition causes dozens, and sometimes hundreds or thousands, of skin cancers on each patient's body. The primary treatment option is surgical removal. These study results are significant as they indicate the possibility of an alternative treatment with oral medication; although side effects remain a consideration.

The phase II clinical study, led by researchers at NewYork-Presbyterian Hospital/Columbia University Medical Center (NYPH/CUMC) and Children's Hospital of Oakland Research Institute (CHORI), was published today in the online edition of the New England Journal of Medicine.

"In its current formulation, vismodegib is appropriate only for BCNS patients with very large numbers of basal cell skin cancers. Still, this is a huge step forward, pointing to the day when we can offer every one of these patients an alternative to repeated surgery, which can be disfiguring and burdensome," said study co-leader David R. Bickers, MD, the Carl Truman Nelson Professor and chairman of dermatology at CUMC and director of dermatology at NewYork-Presbyterian Hospital/CUMC. The study was co-led by Ervin H. Epstein, Jr., MD, a senior scientist at CHORI.

The study is the first to evaluate vismodegib in patients with BCNS. Forty-two patients were randomized to receive either vismodegib (taken orally) or a placebo, for a maximum of 18 months. Overall, the study tracked more than 2,000 existing surgically eligible basal cell skin cancers (SEBs) and documented 694 new SEBs, on the 42 patients.

Patients taking vismodegib experienced an average of 2.3 new SEBs, compared with 29 for patients in the placebo group. Among patients taking t
'/>"/>

Contact: Elizabeth Streich
estreich@columbia.edu
212-305-3689
Columbia University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. One-third of antimalarial medicines sampled in 3 African nations found to be substandard
2. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
3. Highmark Foundation Awards $120,000 to the American Heart Association
4. Stuttering Foundation Hails New Research
5. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
6. Alzheimers Foundation of America Applauds Social Security for Speeding Disability Benefits for Early-Onset Alzheimers Disease
7. Corbett Accel Healthcare Group Mourns Passing of Founder Frank J. Corbett
8. Reliv Foundation Donates $450,000 In Nutritional Supplements to Haitian Relief Efforts
9. Kaiser Foundation Health Plan and Hospitals Report Fourth Quarter and Fiscal Year 2009 Financial Results
10. Instaflex Announces Proceeds Agreement with Arthritis Foundation
11. AMERICAN IDOL to Benefit the UN Foundation Fund for Haiti Thursday, February 25, on FOX
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Delhi, India (PRWEB) August 29, 2014 RBS ... named Remove Scam Book. The service is to help ... negative reviews against them on Scam Book. The service would ... results and make Scam Book complaints fully invisible on Google. ... the service. , On being asked how company can ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 A home should be ... up if unaddressed. That’s why Amica Insurance is sharing some tips ... Safety Council suggests taking the following safety measures: , Kitchen, ... – in their original containers, and keep them away from food. ... wall bracket near an exit. , Bathroom , ...
(Date:8/29/2014)... across the Arabian Peninsula and spread to Europe several ... of several hundred people since its discovery in 2012. ... how easily the pathogen spreads from human to human. ... the University of Bonn have now come to the ... transmission is low. Still, a third of infected persons ...
(Date:8/29/2014)... Glendale Botox experts at Glenoaks ... throughout the month of September. This special offer features 10 ... of Juvederm. Patients can take advantage of this special offer ... Botox experts will work with patients to determine if Botox ... is Botox? , Botox is a treatment made from ...
(Date:8/29/2014)... VHA Central Atlantic recognized Novant ... care, honoring nine facilities for meeting or exceeding national ... Novant Health, providing quality, affordable healthcare for our communities ... MD, executive vice president and chief medical officer. “These ... experience for each and every one of our patients.” ...
Breaking Medicine News(10 mins):Health News:RBS Reputation Management Announces a New Online Reputation Management Service 2Health News:Improve Home Safety with Tips from Amica Insurance 2Health News:MERS: Low transmissibility, dangerous illness 2Health News:MERS: Low transmissibility, dangerous illness 3Health News:Glenoaks Laser Center is Now Offering a Special Promotion on Botox for the Month of September 2Health News:Novant Health Recognized for Excellence in Clinical Care 2Health News:Novant Health Recognized for Excellence in Clinical Care 3
... Poster Presented at Annual Meeting of the American Academy of ... ... 11 NeoStrata today released new,clinical research that validates the benefits ... as a complement to,medical anti-aging treatments such as lasers and microdermabrasion. ...
... research from the UC Davis M.I.N.D. Institute and Center ... the blood of mothers of children with autism bind ... The study authors also found that the reaction was ... form of autism, which occurs when a period of ...
... Deerfield Spa is pleased,to announce the appointment of ... Science., "Jeanine brings outstanding credentials to Deerfield,s ... experience enable her,to fine tune our offerings so ... regimen at the spa, but also learn skills ...
... MyClyns(TM) - the Only Non-Alcohol Product that can be ... Sprayed Directly into the ... today that its revolutionary new product for use after a,potential pathogenic ... upgraded its web site, added a customer,service center and deployed regional ...
... New Patent Expands Geographic Coverage, ... Inc. (OTC Bulletin Board: CARN) today ... granted patent application No. 200600484, titled,"Delivery ... Comprising Anionic,Polysaccharides," relating to the Company,s ...
... University of Oregon scientists say they,ve discovered a ... birth defect in humans that has challenged medical ... zebrafish are present in humans and other vertebrates. ... 10-member research team isolated a disruption in early ...
Cached Medicine News:Health News:NeoStrata Research Validates Anti-Aging Benefits of At-Home AHA Peels As Complement to In-Office Non-Invasive Cosmetic Procedures 2Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 2Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 3Health News:Some cases of autism may be traced to the immune system of mothers during pregnancy 4Health News:Deerfield Spa Appoints New Fitness Director 2Health News:First Responders Acquire Revolutionary MyClyns(TM) Protective Spray 2Health News:First Responders Acquire Revolutionary MyClyns(TM) Protective Spray 3Health News:Carrington's DelSite Drug Delivery Technology Granted Patent From Eurasian Patent Office 2Health News:Carrington's DelSite Drug Delivery Technology Granted Patent From Eurasian Patent Office 3Health News:Oregon researchers discover a mechanism leading to cleft palate 2
(Date:8/28/2014)... NEW YORK , Aug. 28, 2014 /PRNewswire/ ... report is available in its catalogue: ... http://www.reportlinker.com/p02343464/North-America-Laparoscopes-Market-Outlook-to-2020.html North ... GlobalData,s new report, "North America Laparoscopes Market ... the North America Laparoscopes market. The report provides ...
(Date:8/28/2014)... , Aug. 28, 2014 /PRNewswire-iReach/ -- CountryFocus: ... Poland (Photo - ... CountryFocus: Healthcare, Regulatory and Reimbursement Landscape Poland " ... key trends in the healthcare market and provides ... healthcare infrastructure. Most importantly, the report provides valuable ...
(Date:8/28/2014)... Tianyin Pharmaceutical Co., Inc. (NYSE Amex: ... specializes in patented biopharmaceutical, modernized traditional Chinese medicine ... today updates the timeline for the GMP certification ... The Company is scheduled to submit the ... & Drug Administration,s (CFDA) review in the week ...
Breaking Medicine Technology:North America Laparoscopes Market Outlook to 2020 2North America Laparoscopes Market Outlook to 2020 3North America Laparoscopes Market Outlook to 2020 4North America Laparoscopes Market Outlook to 2020 5North America Laparoscopes Market Outlook to 2020 6North America Laparoscopes Market Outlook to 2020 7North America Laparoscopes Market Outlook to 2020 8North America Laparoscopes Market Outlook to 2020 9North America Laparoscopes Market Outlook to 2020 10North America Laparoscopes Market Outlook to 2020 11Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 2Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 3Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 4Poland & Turkey Pharmaceutical Market worth $15 billion & $21.5 billion Respectively by 2020 5TPI Submits Dataset for GMP Inspection at Qionglai Facility (QLF) 2
... Continues Biocatalysis Business Growth With a Further $4m R&D Investment -- CRAIGAVON, Northern Ireland, October 7, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we ...
... N.J., Oct. 7 Novartis Pharmaceuticals Corporation today ... Gilenya™ (fingolimod) 0.5 mg daily, a first-line oral ... was approved by the US Food and Drug ... For people with MS and healthcare professionals seeking ...
Cached Medicine Technology:Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 2Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 3Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 4Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 5Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 6Almac Continues Biocatalysis Business Growth With a Further $4m R&D Investment 7Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 2Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 3Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 4Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 5Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 6Novartis Committed to Supporting Patients and Healthcare Professionals with Education Programs and Support Services that Enhance Access to Gilenya 7
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... ELISA products make us a leader in ... faster integration into the busy laboratory, our ... and run-to-run consistency. Our Infectious Disease ELISA ... wide range of serological assays including ToRCH, ...
... disease ELISA products make us a leader ... for faster integration into the busy laboratory, ... reliability and run-to-run consistency. Our Infectious Disease ... a wide range of serological assays including ...
Medicine Products: