Navigation Links
New discovery on early immune system development
Date:11/12/2013

Researchers at Lund University have shed light on how and when the immune system is formed, raising hope of better understanding various diseases in children, such as leukaemia.

The immune system is complex and a number of genetic diseases are attributed to defects in the cells that form its origins. The study from Lund and Oxford University presents unique findings on the formation of these cells.

We know that the first blood stem cells are formed in the aorta region and then travel to the liver, which is the body's major blood-forming organ during the foetal stage. In the liver, the blood stem cells produce the more mature blood cells that form our blood system. At the same time, T- and B-cells are formed, which comprise the basis of our advanced immune system. From birth, this process takes place in the bone marrow and the liver ceases to form blood cells.

Researchers have long believed that the first cells that lead to the development of our immune system, the immune-competent cells, are formed from blood stem cells in the liver while the foetus is developing. Blood stem cells can be found in the liver from day 11󈝸 in a mouse foetus, which is the equivalent of around 6 weeks' gestation in humans.

In the current study, which was performed on mice, researchers showed that these cells linked to our immune system are formed even earlier than this, in the embryo's yolk sac, i.e. before the first blood stem cells are formed. In the human embryo, the yolk sac is one of the three foetal sacs and appears in around the fifth week of pregnancy.

"The question we have posed is whether the immune system is formed in a different way in the foetus than in an adult and how early in the development of the foetus the cells that form our early immune system can be found. Knowledge of this is important because it helps us to understand how and when our immune system begins to form and what can go wrong in that process", explained Charlott
'/>"/>

Contact: Charlotta Böiers
Charlotta.Boiers@med.lu.se
46-709-436-812
Lund University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Episode of Innovations Airing November 18, 2013 via Discovery Channel
2. OU natural products discovery group asks for publics help with citizen science program
3. Innovations with Ed Begley, Jr. Announces New Episode Airing November 14, 2013 via Discovery Channel
4. New discovery could dramatically reduce leishmaniasis treatment doses and side effects
5. Biosimulation Market (For Drug Discovery & Development) Worth $1.2 Billion by 2017 - New Report by MarketsandMarkets
6. Discovery could lead to anti-clotting drugs with less risk of bleeding
7. International group finds 11 new Alzheimers genes to target for drug discovery
8. Biosimulation Market (Drug Discovery & Development) Worth $1.2 Billion by 2017 - New Report by MarketsandMarkets
9. New Case Management Order in New Jersey DePuy ASR Recall Litigation Extends Discovery to June 2014, More than 650 Metal Hip Lawsuits Filed in Consolidated Proceeding
10. The Producers of the In View Series Announce Upcoming Airing on the Discovery Channel
11. Ethicon Transvaginal Mesh Lawsuits Move Forward, With Scheduling of Discovery Conferences in Federal Vaginal Mesh Litigation, Bernstein Liebhard LLP Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Dallas, Texas (PRWEB) October 20, 2014 ... is the must-have source of thousands of facts, figures ... 72 countries and 68 medical sector forecast categories the ... you with global, regional and national views on the ... future outlook. , The report gives you data for ...
(Date:10/20/2014)... 2014 With a mere 19 days ... made a brief fundraising stop at the  Law ... Fresh from a debate last night with his opponent ... for the first seven minutes because Crist had an ... the incident in one word: "weird." , Before touching ...
(Date:10/20/2014)... 2014 Allegheny General Hospital’s (AGH) Cardiovascular ... physicians to repair a damaged mitral valve as the ... system, developed by Abbott Vascular , is designed ... life-threatening condition in which the heart’s mitral valve leaflets ... from the heart’s left ventricle into the left atrium. ...
(Date:10/20/2014)... 2014 The Advocator Group, LLC ... the American Foundation for Suicide Prevention’s (AFSP) Out of ... a not-for-profit organization that hosts hundreds of community walks ... events are used to help understand and prevent suicide ... relationships as well. , The Advocator Group shares ...
(Date:10/20/2014)... NY (PRWEB) October 20, 2014 ... non-profit organization that helps New Yorkers living with ... changes toward health, housing, recovery and self-sufficiency. Each ... transformed the local community through their tireless efforts. ... Marc Shapses , has been selected as ...
Breaking Medicine News(10 mins):Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 2Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 3Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 4Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 2Health News:Savills Studley's Marc Shapses To Be Honored as 2014 "Positive Changemaker" by ASCNYC 3
... impurities in the chocolate? Have the plastic seams been ... parcel? Answers to all these questions are provided by ... millimeter-wave sensor is able to see through all non-transparent ... Physics and Radar Techniques FHR in Wachtberg have developed ...
... Reporter , TUESDAY, Dec. 20 (HealthDay News) -- Sleep problems ... health issues and poorer performance on the job, a new ... from the United States and Canada online or in person ... disorder. The most common problem, suffered by one-third of ...
... -- Starting aquatic therapy within days after total knee replacement ... for those who,ve had a total hip replacement, according to ... knee and hip replacements is increasing, but there is a ... noted the German researchers. Aquatic therapy has been shown ...
... BRUNSWICK, N.J. Despite improvements to diagnostic tools and ... the diagnosis and treatment of depression remain, according ... Journal of Public Health ; print, February 2012. ... Care in Community-Dwelling Elderly in the United States," lead ...
... News) -- Precautionary measures need to be used in ... sudden death related to overexertion and exhaustion, researchers say. ... due to sickle cell trait during a workout, the ... athletes. University of Michigan researchers evaluated the effect ...
... TUESDAY, Dec. 20 (HealthDay News) -- More Americans now die ... new government report released Tuesday. In 2008, poisoning deaths ... United States and the leading cause of injury death in ... for Disease Control and Prevention. Ninety percent of these ...
Cached Medicine News:Health News:Monitoring food with millimeter waves 2Health News:Many Police Officers Battle Sleep Woes, Study Finds 2Health News:Many Police Officers Battle Sleep Woes, Study Finds 3Health News:Timing of Aquatic Therapy After Joint Replacement Matters 2Health News:Diagnosis, treatment of depression among elderly depend on racial, cultural factors 2Health News:Diagnosis, treatment of depression among elderly depend on racial, cultural factors 3Health News:Screening Alone Not Enough to Prevent Sudden Death in College Athletes 2Health News:Drug Overdoses Kill More Americans Than Car Accidents: CDC 2Health News:Drug Overdoses Kill More Americans Than Car Accidents: CDC 3
(Date:10/20/2014)... , Oct. 20, 2014  PneumRx, Inc. ( www.pneumrx.com ... today announced completion of enrollment in their RENEW Study, ... Study is the FDA-approved IDE pivotal trial for the ... It was anticipated that the study, which ... would take until the end of 2014 to enroll ...
(Date:10/20/2014)... octubre de 2014  PneumRx, Inc. ( www.pneumrx.com ... pulmonología intervencional, anunció hoy la conclusión de la ... antes de lo programado. El Estudio Clínico RENEW es ... investigación (IDE) aprobada por la FDA (Administración de ... de reducción de volumen pulmonar PneumRx RePneu, un ...
(Date:10/20/2014)... BOSTON , Oct. 20, 2014  Indianapolis ... and Toronto -based 3D visualization ... the Congress of Neurological Surgeons Annual Meeting that ... technologies for brain surgery. The collaboration is the ... powerful combination to improve patient outcomes. NICO,s BrainPath® ...
Breaking Medicine Technology:PneumRx Completes RENEW Pivotal Trial Enrollment 2PneumRx Completes RENEW Pivotal Trial Enrollment 3PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5
... & Gamble Company (NYSE: PG ) today announced ... Advisory Panel (SEAP). The new members are: ... Dr. Howard Frumkin – Dean, School of the Public ... Former Secretary, California Environmental Protection Agency ...
... 2011 Following through with plans to expand its Medical ... Florida. Currently operating on a fee for service basis, OMI ... the state. IMD Companies anticipates that OMI will be servicing ... of time. ABOUT IMD COMPANIES, INC. ...
Cached Medicine Technology:P&G Welcomes New Members to U.S. Sustainability Expert Advisory Panel 2P&G Welcomes New Members to U.S. Sustainability Expert Advisory Panel 3IMD Companies, Inc. Announces OMI Operations in Florida 2
... a bioresorbable implant that is used for ... This proprietary, user-friendly design, shaped like a ... into burr holes and requires no fixation ... superior mechanical strength and the scaffold architecture ...
NIVEA body Good-bye Cellulite Gel-Cream visibly reduces the appearance of cellulite....
... tubes are heparinized glass capillary ... film. These tubes are used ... blood samples for the measurement ... electrolytes (excluding lithium) and can ...
... implant is a sterile off white, moist, ... porcine collagen and its constituent elastin fibres ... implant comes ready to use in double ... impermeable to oxygen, and is sterilised by ...
Medicine Products: