Navigation Links
New discovery may lead to immunization against cardiovascular disease
Date:7/31/2008

Low levels of naturally occurring antibodies may represent an increased risk of developing cardiovascular disease, particularly stroke in men. This discovery, published in the academic journal Atherosclerosis, has now led to attempts to develop an immunization against cardiovascular disease.

Atherosclerosis (hardening of the arteries) is an inflammatory disease in which the walls of the blood vessels are thickened and become less elastic. It can cause blood clots and other cardiovascular diseases. It is not known precisely what causes atherosclerosis, but the immune system probably plays an important role. Research scientists suspect that various oxidised forms of what is known as bad cholesterol, LDL (low-density lipoprotein), contribute to the development of the disease. A research team from Karolinska Institutet, in cooperation with Lund University, has now shown that a particular type of naturally occurring antibodies, anti-PC, which are targeted against the lipid portion of the LDL molecule, play an important role in the development of cardiovascular disease.

The findings show that individuals who have low levels of anti-PC are at increased risk of cardiovascular disease. The risk is particularly high in men who develop stroke, with an almost fourfold increase.

This newly discovered risk factor, low levels of anti-PC, is independent of previously known risk factors such as high blood pressure, high blood lipids, diabetes and smoking.

"Our findings suggest that anti-PC can be used as a complement to the traditional risk factors to improve diagnosis and treatment. In addition we are currently developing anti-PC as a vaccine for atherosclerosis and cardiovascular disease," says Professor Johan Frostegrd, who directed the study.

The study is based on data from 349 people who at some time over a 12-year period have suffered a heart attack or stroke and 693 individuals without symptoms of cardiovascul
'/>"/>

Contact: Sabina Bossi
sabina.bossi@ki.s
46-085-248-6077
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The First Surviving Set of African American Sextuplets To Be Profiled on Discovery Healths Then Came 6
2. Fox Learning Systems Selects Prymaks Discovery-180(TM) Technology Assessment to Guide Search for New LMS
3. Discovery first step to new therapies
4. Discovery of key malaria proteins could mean sticky end for parasite
5. 9/11 Workers Refute Citys Allegation of Discovery Abuse and Malingering
6. Discovery of gene mechanism could bring about new ways to treat metastatic cancer
7. MYSTERY ER Season 2 Takes Viewers Behind the Curtain for Real-Life Medical Mysteries on Discovery Health
8. NIAID creates HIV vaccine discovery branch
9. Could new discovery about a shape-shifting protein lead to a mighty morpheein bacteria fighter?
10. Core Informatics Deploys Core LIMS to Support Antibody Discovery at Fabrus
11. Dynamin drug discovery team win prestigious international epilepsy grant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... A new study in the American Journal of ... searches reveals a recurring pattern that could be leveraged ... from San Diego State University, the Santa Fe Institute, ... Google searches (searches that included the term healthy and ... U.S. from 2005 to 2012. They found that on ...
(Date:4/17/2014)... Men who show signs of chronic inflammation in non-cancerous ... actually having prostate cancer than those with no inflammation, ... researchers from the Johns Hopkins Kimmel Cancer Center. , ... stronger for men with so-called high-grade prostate cancer ... indicating the presence of the most aggressive and ...
(Date:4/17/2014)... to a study published today in PLOS Pathogens ... where malaria is common can mount an immune response ... to avoid repeated bouts of high fever and illness ... their bloodstream. The findings may help researchers develop future ... the malaria parasite. , Each year, approximately 200 million ...
(Date:4/17/2014)... published in the April issue of Immunity , ... for Medical Research, says it,s time to take a ... treating sepsis, which kills millions worldwide every year, ... molecules released into the bloodstream to fight an injury ... necessary for maintaining good health without inflammation, wounds ...
(Date:4/17/2014)... MAYWOOD, Il. (April 17, 2014) Doctors who ... disease called lymphangioleiomyomatosis (LAM) can face an agonizing ... progression of the disease and help relieve shortness ... lung transplants, and sirolimus can cause potentially fatal ... said pulmonologist Dr. Daniel Dilling, medical director of ...
Breaking Medicine News(10 mins):Health News:New research shows people are thinking about their health early in the week 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3
... Clinicians to Overcome the Limitations of Conventional Pulse Oximetry, ... Calif., June 3 Masimo, the inventor of Pulse ... announced it has completed the conversion of Duke ... , , "Ultimately, the decision to convert ...
... ... for Christian Community. Christian Care Ministry, Inc. is a not-for-profit religious organization that facilitates ... ... 2009 -- Medi-Share is a member-based program where members share in each ...
... Genetics is pleased to announce the launch of whole-genome ... Oligo Array, which is designed to identify chromosomal abnormalities ... partnership with Baylor College of Medicine , Ambry ... comprehensive, clinically-validated genetic tests available using array comparative genomic ...
... Lauded in Healthcare Category for ,Visionary Application of Information ... , , MADISON, N.J., June 3 ... world,s leading provider of diagnostic testing, information and services, ... Ltd. has been recognized as a Laureate by the ...
... , WASHINGTON, June 3 New questions and valuable answers ... at www.tenquestionstoanswer.org , the latest in the Heinz Family Philanthropies ... designed to help families make the best long-term care decisions. Available ... manage long-term care. , , "We want ...
... STAMFORD, Conn., June 3 FUJIFILM Medical Systems ... today that the company has taken several steps ... company is already an experienced virtualization provider with ... successfully implemented across the U.S. Now, to ...
Cached Medicine News:Health News:Leading University Hospital Completes System-Wide Conversion to Masimo SET(R) Pulse Oximetry 2Health News:Leading University Hospital Completes System-Wide Conversion to Masimo SET(R) Pulse Oximetry 3Health News:Leading University Hospital Completes System-Wide Conversion to Masimo SET(R) Pulse Oximetry 4Health News:Medi-Share Program Announces New Healthcare Program Offerings for Christian Community 2Health News:'Ambry Genetics Announces Launch of Chromosomal Microarray to Offer Whole Genome Analysis' 2Health News:'Ambry Genetics Announces Launch of Chromosomal Microarray to Offer Whole Genome Analysis' 3Health News:Quest Diagnostics India Recognized as Laureate by the Computerworld Honors Program 2Health News:Quest Diagnostics India Recognized as Laureate by the Computerworld Honors Program 3Health News:Quest Diagnostics India Recognized as Laureate by the Computerworld Honors Program 4Health News:New From the Heinz Family Philanthropies: 10 Questions and Valuable Answers to Help Families Manage Long-Term Care 2Health News:New From the Heinz Family Philanthropies: 10 Questions and Valuable Answers to Help Families Manage Long-Term Care 3Health News:New From the Heinz Family Philanthropies: 10 Questions and Valuable Answers to Help Families Manage Long-Term Care 4Health News:New From the Heinz Family Philanthropies: 10 Questions and Valuable Answers to Help Families Manage Long-Term Care 5Health News:Fujifilm Takes Virtualization Technology to Next Level 2Health News:Fujifilm Takes Virtualization Technology to Next Level 3
(Date:1/15/2014)... GARDENS, Fla. , Jan. 15, 2014  In an unprecedented effort ... and TB in ambulances and other transport vehicles, an advanced and ... by rescue personnel for the first time. In ... contact with these deadly pathogens, West Palm Beach ...
(Date:1/15/2014)... 2014 The Cadence Fitness & Health Center has ... Medical Fitness Association, a non-profit organization assisting medically integrated ... The Cadence Fitness & Health Center is the only ... in the Chicagoland area. "The certification means ...
(Date:1/15/2014)... LAVAL, Quebec , Jan. 15, 2014  Valeant Pharmaceuticals ... VRX) announced that the applicable waiting period under the ... to the previously announced tender offer by its indirect ... the outstanding shares of common stock of Solta Medical, ...
Breaking Medicine Technology:Superbugs No Longer Ride In Rescue Vehicles 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... COLUMBUS, Ohio, June 15, 2011 EndoSphere Inc. ... and international issued and pending patents, announced today that ... company a patent covering the use of its endoscopically ... obesity and type 2 diabetes. U.S. Patent ...
... Corp. (the "Company") (NASDAQ OTC: VSHC) is pleased to be ... fourth quarter of fiscal 2011 to be between $1,050,000 and ... high since inception and represents a substantial increase from previous ... provide further guidance regarding year end revenues for the entire ...
Cached Medicine Technology:EndoSphere Inc. Receives Patent for Obesity Treatment 2Visual Healthcare Provides Fourth Quarter Revenue Guidance 2
Specimen-ID™, a Positive Specimen Identification System, assures the permanent link at the bedside between patient and laboratory specimen to prevent sample identification errors....
... The CAREt™ System is a ... state-of-the-art medication safety while improving ... assists in managing a myriad ... hand-held device linked real-time to ...
wCareMed™ utilizes barcode scanning technology to support medication administration. It is a simple to use point of care application that provides access to patient information on a lightweight,...
Med Administration Check closes the loop on the medication use process by automatically validating and documenting medication administration....
Medicine Products: