Navigation Links
New discovery in fight against deadly meningococcal disease
Date:5/23/2013

"Neisseria meningitidis is an important human pathogen that can cause rapidly progressing, life threatening meningitis and meningococcal sepsis in humans," Professor Jennings said.

"Until now we have not known how it attaches to the human host. It has been a long-standing mystery how it attaches to the airway to colonise"

People can be carriers of the bug and not get any symptoms, while some people progress to invasive disease. To understand why, we need to know the detail of how the bacterium colonises the airway. Now that the pathway has been identified we can study this process to understand how invasive disease occurs. This is especially important considering the rapidly progressing and serious outcomes of meningococcal disease.

"If you understand how the bug first attaches and how it first signals its attachment then we may identify new risk factors or treatment procedures," Professor Jennings said.

The findings were published Friday in the highly regard PLOS Pathogens journal as featured research "Dual Pili Post-translational Modifications Synergize to Mediate Meningococcal Adherence to Platelet Activating Factor Receptor on Human Airway Cells."

The paper states: There is no fully protective vaccine against this pathogen in current use and the key processes that dictate the transition from harmless carriage of the bacterium in the airway (the case for the vast majority of colonised hosts) to invasive disease are largely undefined. A key missing link in this organism's interaction with the human host is the identity of the receptor that is the first point of contact for the organism within the airway.

Professor Jennings said the receptor is used by a range of airway pathogens and the bacterium mimics a human structure to attach to this receptor.

"It's not actually protein that attaches to the receptor but decor
'/>"/>

Contact: Helen Wright
helen.wright@griffith.edu.au
047-840-6565
Griffith University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
2. Washingtons Life Sciences Discovery Fund awards commercialization grants
3. Discovery could help to develop drugs for organ transplant and cancer patients
4. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
5. H1N1 discovery paves way for universal flu vaccine: UBC research
6. Scientists make breakthrough in bile duct cancer with discovery of new gene mutations
7. Researchers make promising discovery in pursuit of effective lymphoma treatments
8. Discovery suggests new combination therapy strategy for basal-like breast cancers
9. Discovery of Gene May Lead to New Male Contraceptive
10. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
11. Illnesses in Colorado childrens hospital prompts discovery of contaminated alcohol pads
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2015)... BC (PRWEB) May 25, 2015 According ... http://www.idataresearch.com ), market growth in hip external fixation market ... the aging U.S. population and advancements in infection prevention ... increases. These fractures are currently accounting for the largest ... commonly associated with falls and accidents. As a result, ...
(Date:5/25/2015)... San Rafael, CA (PRWEB) May 25, 2015 ... Field for a free two-hour instructional clinic. Irish National ... with campers and give them a taste of her coaching ... San Anselmo and Novato. Camps in Novato are at Lynwood ... 3). , Novato High School - June 6th, 2015 ...
(Date:5/24/2015)... Pacific Prime has announced that they have launched the ... the cost of individual international health insurance. Titled: The Cost of ... cost of health insurance in six top expat destinations, which are ... Hong Kong , Singapore , China ... the UK , Article 2 presents an in-depth ...
(Date:5/24/2015)... Raleigh, NC (PRWEB) May 24, 2015 ... published a paper on air quality compliance issues that ... of American workers. Surviving Mesothelioma has just posted an ... it now. , The group found airborne asbestos ... inspection data collected between 1984 and 2011. , “Asbestos ...
(Date:5/24/2015)... May 24, 2015 Medicx Media ... Media strategy executive Jay Krihak as its head ... to ramp up its expertise and leadership position ... Pharmaceutical and Health sectors. , Krihak is an ... Most recently, Krihak led sales planning teams for ...
Breaking Medicine News(10 mins):Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 2Health News:DePuy Synthes and Stryker Lead Orthopedic External Fixation Trauma Device Market Due to Increased Hip Fractures in the U.S. 3Health News:US Sports Camps and Nike Soccer Camps Offer Complimentary Instructional Clinic with Fiona's Soccer Camp 2Health News:Pacific Prime Releases 2nd Article of Cost of Health Insurance Report 2Health News:New Analysis Finds Too Many Employers Ignored OSHA Asbestos Guidelines, According to Surviving Mesothelioma 2Health News:Medicx Media Solutions Expands Executive Team 2
... ... Products LLC is proud to announce the unveiling of its brand ... prices directly to the American Consumer. TouchstoneSaunas.com offers premium quality ... home. Constructed from the highest quality materials to provide many ...
... ... and Earth Day Celebration Saturday, April 17. , ... Golden, CO (PRWEB) April 17, 2010 -- Panorama Orthopedics & Spine ... and Arbor Day April 17. As part of its companywide green initiative, launched last year, ...
... As a ... team of expert negotiators who will act as buying agents for their elite group of ... New York, NY ... The Leading Physicians of the World is even further empowering their members by representing their ...
... A major ... debate surrounding the provision of open educational resources (OER) by revealing the key factors surrounding ... ... Dr Ann Hemingway investigated the barriers and enablers of free online public health education as ...
... ... Success , ... MA (Vocus) April 16, 2010 -- Blue Cross Blue Shield of Massachusetts ... over 160 firefighters in seven cities/towns (Arlington, Framingham, Hingham, Hudson, Ludlow, Peabody and Rockland) ...
... (April 15, 2010) -- Nine-year-old Morgan LaRue is the first ... that will magnetically lengthen her leg, sparing her the possibility ... The implant and extension took place at Texas Children,s Cancer ... Children,s Cancer Center or the device, please see http://bit.ly/MorganLaRue ...
Cached Medicine News:Health News:Touchstone Saunas Goes Online to Provide Premium Quality Infrared Saunas 2Health News:Panorama Orthopedics and the City of Westminster Join Forces to Improve the Environment through Tree Giveaway 2Health News:Exclusive Medical Organization, The Leading Physicians of the World Negotiates Equipment Contracts on Their Members Behalf 2Health News:BU Study Contributes to Online Health Education Debate 2Health News:BU Study Contributes to Online Health Education Debate 3Health News:Firefighters Walk Over 60,000 Miles in Blue Cross Blue Shield of Massachusetts' Fitness Challenge 2Health News:Firefighters Walk Over 60,000 Miles in Blue Cross Blue Shield of Massachusetts' Fitness Challenge 3Health News:Firefighters Walk Over 60,000 Miles in Blue Cross Blue Shield of Massachusetts' Fitness Challenge 4Health News:Texas Children's Cancer Center first in Texas to magnetically lengthen 9-year-old's leg as she grows 2
(Date:5/22/2015)... InspireMD, Inc. (NYSE MKT: NSPR) ("InspireMD" or the "Company"), ... that its CGuard TM Embolic Prevention System reported positive ... Musialek , at the EuroPCR conference on May ... PARADIGM, an investigator-initiated P rospective evaluation of ... revascularization I n symptomatic and increased-risk asymptomatic carotid artery ...
(Date:5/22/2015)... Richmond Pharmacology is a ... a worldwide reputation for excellence in clinical trials. ... peer reviewed medical journals. Its officers are engaged ... discussions about rules for transparency and publication of ... , Clinical research is conducted worldwide, ...
(Date:5/21/2015)... CHICAGO , May 21, 2015 /PRNewswire-USNewswire/ ... lump along the side of his neck, ... and took a couple weeks off from ... didn,t go away.                               ... Rendino, 26, was referred to Michel ...
Breaking Medicine Technology:InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 2InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 3InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 4Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 2Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 4
... LAWRENCE, Mass., Nov. 9, 2010 NxStage Medical, ... manufacturer of innovative dialysis products, today announced that ... Brown, Chief Financial Officer, will participate in the ... Healthcare Summit Boston Harbor Hotel Boston, MATuesday, November ...
... ATLANTA, Nov. 9, 2010 The addition of ... associated with a rapid clinical response, improved function ... of adult rheumatoid arthritis (RA) patients reflecting those ... prior TNF-inhibitor use).  These positive clinical trial data ...
Cached Medicine Technology:NxStage Announces Fourth Quarter 2010 Investor Conference Schedule 2New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 2New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 3New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 4New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 5New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 6New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 7New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 8New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 9New Cimzia® (certolizumab pegol) Data Show a Significant, Rapid Clinical Response and Reduced Disease Activity Among Diverse Patient Populations With Active Rheumatoid Arthritis (RA) 10
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
This is a single-action instrument that features a spring handle....
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
Medicine Products: