Navigation Links
New devices to boost nematode research on neurons and drugs
Date:2/6/2008

A pair of new thin, transparent devices, constructed with soft lithography, should boost research in which nematodes are studied to explore brain-behavior connections and to screen new pharmaceuticals for potential treatment of parasitic infections in humans, report 10 scientists at three institutions.

The tools -- an artificial soil device and a waveform sampler device, both of which can be held easily in a human hand -- are detailed in a paper appearing online ahead of regular publication by the Journal of Neurophysiology.

The devices take advantage of a microfluidic fabrication technique, which allows for the presence of channels, chambers or ports, for gas permeability and transparency and for using fluids to deliver stimuli with precision. The major improvement over previous tools is that these new ones are agarose-free, using micron-scale channels and pillars that mimic real soil particles.

The newly reported devices provide a near natural environment for soil-dwelling roundworms (Caenorhabditis elegans, or C. elegans) that measure barely a millimeter in length. The nematodes move normally, but slightly compressed so that highly sensitive microscopes can be used to monitor individual fluorescent-injected neurons in real time during experiments.

"There is a commonality between these devices that is really going to help us understand how the nervous system works," said lead researcher Shawn Lockery, a professor of biology and member of the Institute of Neuroscience at the University of Oregon.

"The artificial soil device consists of a hexagonal array of microscopic pillars sandwiched between a glass cover slip and a bulk material from which the pillars protrude," Lockery said. "The worm wanders around in a one-centimeter square area as a river of mostly water flows through it. We can change the solution the nematode is exposed to in ways that are relevant to the research that is being conducted."

For i
'/>"/>

Contact: Jim Barlow
jebarlow@uoregon.edu
541-346-3481
University of Oregon
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Integrated Laser Therapies Launches, Offers Low-power, Therapeutic Laser Devices and Training for Therapists and Consumers
2. GPS Devices Measure Severity of Peripheral Artery Disease
3. QED International Associates Announces Changes to the HealthShares(TM) European Medical Products and Devices Index
4. Hiemstra Approved to Manufacture Medical Devices in New CER
5. SYMLIN Pen-Injector Devices Now Available
6. Advertisements for Medical Devices, Implants Should Carry Warnings of Dangerous Side Effects, Infections
7. Radiology Support Devices Introduces New Breathing Phantom System
8. SPO Medical Unveils New Oximetry Devices for European Markets
9. Hazardous Advanced Micro Devices (A.M.D.) Clean Room Chemicals Caused Multiple Birth Defects, Lawsuit Alleges
10. DeviceSpace Career Fair Opens Doors for Hundreds of Medical Device and Diagnostics Career Candidates
11. QED International Associates Announces Changes to the HealthShares(TM) Composite, HealthShares(TM) Cardio Devices, and the HealthShares(TM) Orthopedic Repair Indexes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New devices to boost nematode research on neurons and drugs
(Date:7/11/2014)... 11, 2014 As transvaginal mesh ... Johnson & Johnson’s Ethicon Inc. unit continue to ... that the Texas Attorney General’s Office has acknowledged ... surgical mesh products used to treat pelvic organ ... report from kens5.com, the probe began nearly two ...
(Date:7/11/2014)... (HealthDay News) -- People with the lowest incomes may have ... disease (PAD), a new study suggests. People with PAD ... limbs, most often the legs. The condition causes leg pain ... throughout the body. People with PAD have a higher risk ... nearly 6,800 people with PAD who took part in the ...
(Date:7/11/2014)... UK (PRWEB) July 11, 2014 Microbiology ... of the in-vitro diagnostics industry, which is expected to ... ten years. The sector owes its growth to the ... to people’s health worldwide and a major factor leading ... technologies, threat of bio-terrorism, and a broader availability of ...
(Date:7/11/2014)... The Europe Well Intervention Market report defines ... analysis and revenue forecast. The well intervention services market in ... 2013 to $3.4 billion by 2018, at a CAGR of ... of the Europe Well Intervention Market report, to get an ... glimpse of the segmentation in the Europe well intervention market, ...
(Date:7/11/2014)... MA (PRWEB) July 11, 2014 ... at least $50 billion in fuel costs ... immediately. The current GHG standards ... have taken it upon themselves to install ... include: , 1.    Idle reduction technologies , 2.    Efficient ...
Breaking Medicine News(10 mins):Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 2Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 3Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 4Health News:Poor More Prone to Leg Circulation Trouble 2Health News:World Virology and Bacteriology Testing Sector Discussed in Comprehensive VPG Research Report Published at MarketPublishers.com 2Health News:World Virology and Bacteriology Testing Sector Discussed in Comprehensive VPG Research Report Published at MarketPublishers.com 3Health News:Europe Well Intervention Services Market is Expected to Reach $3.4 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:Europe Well Intervention Services Market is Expected to Reach $3.4 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 2Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 3
... Oriental medical practice of Acupuncture along with commonly ... disabling side effects of chemotherapy for breast cancer ... (NIH) are to be believed. , , ,According ... NIH, electro-acupuncture was more effective in controlling vomiting ...
... causing 160,000 deaths annually from lung, mouth, bladder and other ... of the colon or rectum, according to results of a ... ,As many as 12% of all colorectal cancer deaths in ... cancer is not currently considered a smoking-related cancer, but data ...
... is often difficult to diagnose and many a times ... reaction (PCR) is emerging as a promising technique for ... of bacteria by facilitating rapid amplification of small amounts ... the Millennium International Urology Congress in India. Presence ...
... prescription drug, levothyroxine sodium (Unithroid) for hypothyroidism in adults ... States by the FDA. , ,The thyroid hormaone ... metabolic processes within the body in all age groups. In ... intellectual development. , ,Low levels of thyroid hormone or ...
... has become an ever-growing menace on the Internet. ... have listed 500 health related web-sites that are ... serve as a guideline for surfers to be ... sites. The information can be accessed on http://www.ratbags.com/rsoles/categories.htm, ...
... after the start of an El Ni?o event in ... ,Bangladesh can expect a surge of cholera cases, according ... with subsequent ,cholera outbreaks. , ,Details of the ... of the journal Science by ecologists at Cornell University ...
Cached Medicine News:Health News:El Ni?o cycles linked to cholera outbreaks , 2
(Date:7/10/2014)... Virginia , 11. Juli 2014 ... von Kameras für die molekulare Bildgebung, ... hat heute die CE-Zulassung für sein ... CE-Zeichen kann Dilon das Produkt jetzt ... auf den Großteil der europäischen Länder ...
(Date:7/10/2014)... 2014  Breg, Inc., a premier provider of ... FreeRunner™ knee brace with new innovations to help ... return to active lifestyles.  FreeRunner,s patent-pending design acts ... support when patients need it most, and the ... Patellofemoral issues are the most common cause ...
(Date:7/10/2014)... , July 10, 2014  RESMED INC. (NYSE: ... quarter and fiscal year ended June 30, 2014 results on ... market close. A press release with ResMed,s results will be ... will host a webcast to discuss operating results and future ... at 1:30 p.m. US Pacific Time and the live webcast ...
Breaking Medicine Technology:Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2
... technology has enabled more and more laboratory testing to ... laboratory is hardly threatened with extinction. National volume data ... ever before, and the huge range of their capabilities, ... volumes of tests assures them an abiding and pivotal ...
... S. Singer, M.D., Ph.D. Harvard Medical School ,Contributing ... and 40,000 deaths per year, breast cancer undoubtedly ... problems. Recently, efforts to develop early detection ... progress. This is particularly true at the ...
Cached Medicine Technology:Immunoassay Systems - Your Laboratory Workhorse 2Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy 2Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy 3
The PDC Smart® Key Fob can be programmed on demand using a 13.56 MHz RFID reader/writer and is ideal for long-term use applications such as electronic access control or loyalty programs....
... provide healthcare professionals witha patient'sname and ... speak, cant remember, oris unconscious. VeriMed ... individuals. The application can help these ... comparable level of care by rapidly ...
... The optional Kisses component of ... to assist nursing staff in ... while in the hospital. ... have an easy, effective and ...
VerdaSee Portal ID is a family of solutions that provide automated tracking and tracing of assets as they enter or leave designated areas within a healthcare facility....
Medicine Products: