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New developments in biomarkers for epithelial ovarian cancer

AMSTERDAM, November 29th 2007 With the genomic revolution radical improvement has been made in methods of detection of ovarian cancer. This is of the utmost importance, since the chances of successful treatment are strongly enhanced with early detection. In a special issue of Disease Markers, published by IOS Press, eleven articles explore new developments in the identification and understanding of biomarkers for epithelial ovarian cancer.

Many of these biomarkers may serve not only as markers of clinical and biology interest but also as potential therapeutic and imaging targets which could significantly improve the survival of patients with this disease, states Prof. Michael J. Birrer (National Cancer Institute, Center for Cancer Research, Cell and Cancer Biology Department, MD, USA).

Discussed in the issue are new hypotheses on the molecular development of ovarian cancer, SP markers of risk, biomarkers that are specific for the different histological subtypes, and new biomarkers and approaches for the early detection of ovarian cancer. Furthermore, new molecular technologies have allowed for the analysis and characterization of specific cellular components of ovarian tumors identifying biomarkers of tumor associated immune and endothelial cells.


Contact: Wilbert van der Sluijs
IOS Press

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