Navigation Links
New data on hormone therapy must lead to re-evaluation of official guidelines
Date:10/18/2007

As opinion leaders in the field of menopause medicine from various areas in the world, we wish to emphasize the following points concerning postmenopausal hormone therapy:

  1. Hormone therapy (HT) remains the most effective treatment for vasomotor symptoms and estrogen-deficient urogenital symptoms.

  2. The initial interpretation of the Womens Health Initiative (WHI) trial failed to recognize the immense importance of age and years since menopause on outcomes of HT. The potential impact of specific hormonal regimens on safety of HT should be considered as well.

  3. The results of the WHI trial were wrongly extrapolated to the whole postmenopausal population, which led to a major change in recommendations and guidelines on HT.

  4. Based on current knowledge, the balance between the benefits and risks of HT is clearly in favor of use in the early postmenopausal years for symptomatic, healthy women.

  5. All previous studies, including the WHI trial, have demonstrated significant positive effect on bone density and reduction in fracture risk among hormone users.

  6. Estrogen has favorable metabolic and cardioprotective effects in healthy, young postmenopausal women. The results for the age group 5059 years in the WHI estrogen-alone arm support this claim. Estrogen slows the pace of development of atherosclerosis if started in the early postmenopausal period.

  7. HT may be associated with a small increase in risk for breast cancer, if taken long term. Combined estrogenprogestogen therapy probably carries a higher risk than that recorded for estrogen alone. Prevalence of stroke and thromboembolism strongly correlates with age; therefore, the impact of the HT-related increased risk in this respect becomes more important in the late menopause. Low-dose estrogen or the transdermal route of administration may lead to a more favorable risk profile.

  8. Progestins, combined with estrogen, may d
    '/>"/>

Contact: Jean Wright
jwright.ims@btopenworld.com
International Menopause Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Thyroid hormone treatment hastens recovery after cardiac surgery
2. Levothyroxine Thyroid Hormone Replacement, Approved for Hypothyroidism
3. Hormone replacement Therapy a headache
4. Ovarian cancer in relationship with Hormone therapy
5. Evaluating The Risks and Benefits of Hormone Therapy
6. Scientists crack mechanism of Leptin-Obesity Hormone
7. Scientists use plant hormones to fight cancer
8. Use parathyroid hormone to fight brittle bone disease
9. Multiple Sclerosis Can Be Treated By Blocking Fat Hormone
10. Hormone contraceptives lead to bone problems
11. Hormone treatment helps obese people slim down
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2015)... ... August 29, 2015 , ... Hamstring ... area with stretching, soft tissue manipulation. Platelet rich plasma injections also have ... research to improve treatment outcomes. This localized treatment seems to address the ...
(Date:8/29/2015)... ... 29, 2015 , ... Vascular Health Sciences announced today that ... Arterosil HP, and that all claims and counterclaims have been irrevocably dismissed. , ... in the United States District Court for the Southern District of Texas for ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... center management, Decatur County Memorial Hospital recently transitioned management companies to partner with ... Center Management for their outpatient wound center. , Transitioning wound care management ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... at the Zoo to celebrate children helping children, a thank you to the ... West Ohio have contributed to the United Methodist initiative to end malaria deaths. ...
(Date:8/28/2015)... , ... August 28, 2015 , ... An article ... local pizza maker Paul LaRocco has gone through to open a pizzeria in Westchester. ... permitting process tends to take several months, but the current process, having already gone ...
Breaking Medicine News(10 mins):Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 2Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2
... Conn. Yale scientists have discovered the molecular pathway ... DNA mutations trigger a signaling cascade, resulting in programmed ... issue of Cell . Mitochondria are cellular ... generate most of the cell,s supply of energy. They ...
... HealthDay Reporter , THURSDAY, Feb. 16 (HealthDay News) ... anymore. In a new small study, women with severe ... drugs at the push of a button, a delivery ... conditions. Roughly 1.5-by-2.5 inches in size, the microchip ...
... patients with septic shock is safe and decreases vasopressor ... from researchers in France. "The benefits and ... remains a matter of controversy," said lead author Frdrique ... Crteil, France. "In our study, external cooling to achieve ...
... Montaner of the British Columbia Centre for Excellence in ... in this week,s PLoS Medicine that the cost-effectiveness of ... analyses have not yet taken into account the beneficial ... The authors comment: "the strategic value of expanded ...
... -- Most men who have surgery for prostate cancer can ... gland are not removed, according to a new study. ... number of his nerves that are spared will play a ... study followed 408 men who underwent a procedure to remove ...
... and grading, schoolteachers have a demanding job, and lately it,s ... challenges, thousands of Florida educators rely on a free, online ... teaching tools and resources, just when they need them. Soon ... Department of Education using federal Race to the Top funds ...
Cached Medicine News:Health News:How mitochondrial DNA defects cause inherited deafness 2Health News:Implanted Microchip Might Be Future of Drug Delivery 2Health News:Implanted Microchip Might Be Future of Drug Delivery 3Health News:Fever control using external cooling reduces early mortality in septic shock patients 2Health News: Nerve-Sparing Prostate Surgery Helps Men Retain Sexual Function 2Health News:$10.5 million grant will expand vast online hub for educators, by educators 2Health News:$10.5 million grant will expand vast online hub for educators, by educators 3Health News:$10.5 million grant will expand vast online hub for educators, by educators 4
(Date:8/28/2015)... 2015  CytomX Therapeutics, Inc., a biopharmaceutical company developing ... the filing of a registration statement on Form S-1 ... to a proposed initial public offering of its common ... the price range for the offering have not yet ... under the symbol "CTMX" on the NASDAQ Global Market. ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... ) has announced the addition of the ... report to their offering. Originally discovered ... as Yoshitomi Pharmaceutical Industries, Ltd) as an inflammatory ... by Senju Pharmaceutical Co., Ltd under the trade ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... ) has announced the addition of the ... Capacity and Production" report to their offering. ... Survey of Biopharmaceutical Manufacturing Capacity and Production is ... contract manufacturing organizations, current and projected future capacity ...
Breaking Medicine Technology:CytomX Files Registration Statement for Proposed Initial Public Offering 2Investigation Report on China's Pranoprofen Market, 2010-2019 212th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2
... N.C., June 20, 2011 Pharmaceutical Institute, the ... pharmaceutical and biotech industry and a subsidiary of ... updates to its Therapeutic Area Essentials™ ... disease state training for pharmaceutical and biotech R&D ...
... dreamed of becoming a pilot for as long as he can ... child opting to play with toy planes instead of cars, and ... a family trip to Disney World.  At 8-years old Baniecki scribbled ... airline pilot and placed it into a time capsule.  Ten years ...
Cached Medicine Technology:Therapeutic Area Essentials "Class of 2011" Brings Current Disease State Training to Pharma 2Pilot's Dream Comes True Thanks to New Robotic Surgery 2Pilot's Dream Comes True Thanks to New Robotic Surgery 3Pilot's Dream Comes True Thanks to New Robotic Surgery 4
Stedman's Medical Dictionary includes charts and tables and navigation and search tools....
English and Spanish translations of all medical terms and phrases used in clinician-patient interactions....
ICDMeister is an electronic reference containing 15,000 of the 2006 ICD-9-CM diagnosis codes. Use whichever of the four different approaches for finding codes that you ....
CPTMeister is a coding reference based on the Physicians' Current Procedural Terminology (CPT) codes developed by the American Medical Association. It is an iSilo document composed of more than 2,000...
Medicine Products: