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New data demonstrate potential for early detection of Alzheimer's disease
Date:6/16/2009

MONTREAL, CANADA, JUNE 16, 2009 Data published in the June issue of the Journal of Alzheimer's Disease demonstrated that minimally-invasive biospectroscopy was able to identify changes in oxidative stress (OS) levels in blood plasma, which may prove to be a useful biomarker in the early detection of Alzheimer's disease. There is currently no accepted laboratory test for diagnosing Alzheimer's disease.

Researchers at McGill University and the Lady Davis Institute for Medical Research (LDI) at the Jewish General Hospital (Montreal, Canada), have shown that near-infrared (NIR) biospectroscopy can identify a chemical signature, or biomarker, in blood that distinguishes Alzheimer's disease from normal aging and possibly other neurodegenerative conditions. Diagnosis of Alzheimer's disease is currently based solely on a patient's medical history and neurological examination, is labor-intensive and expensive, and often inconclusive in early stages of the illness. The availability of a biologic marker that reliably differentiates Alzheimer's disease from normal aging and other dementing conditions would represent a major achievement in the management of this common neurodegenerative disorder.

"There is an urgent need for an accurate diagnostic test to aid in the early diagnosis and management of Alzheimer's disease," said Hyman M. Schipper, MD, PhD, FRCPC, lead author of the study and Professor of Neurology and Medicine at McGill University. Dr. Schipper is also Founding Director of the Centre for Neurotranslational Research and a member of the Bloomfield Centre for Research in Aging at the LDI. "Our observations give us hope that biospectroscopy will offer a new approach to the early diagnosis of Alzheimer's disease and other neurodegenerative disorders." Dr. Schipper is a noted expert in brain aging and neurodegeneration. Dr. David Burns of the Department of Chemistry at McGill University, an experienced biospectroscopist, was a co-investigat
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Contact: Gina Cella
ginacella@comcast.net
781-334-4692
IOS Press
Source:Eurekalert

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