Navigation Links
New criteria for measuring tumor size and progression will help ease workloads in clinical trials
Date:1/19/2009

The first, formal revision of specific guidelines, known as RECIST, used by clinicians to measure tumour size and response to treatment, has been published today (Tuesday 20 January) in a special issue of the European Journal of Cancer [1]. The authors say that the revisions will ease the workload involved in running clinical trials, without compromising study outcomes.

RECIST (Response Evaluation Criteria in Solid Tumours) were first published in 2000 and are used by investigators in phase II and phase III clinical trials of new anti-cancer drugs as a way of measuring the efficacy of the treatment. Tumour shrinkage (objective response) and time to the development of disease progression are both important endpoints in trials, and, increasingly in recent years, trials have been using time to progression (or progression-free survival) as their main endpoint on which to base conclusions about the efficacy of a drug.

The new RECIST (RECIST 1.1 to distinguish them from the original RECIST) answer some of the questions and issues that have arisen since 2000 as a result of changing methodologies and available treatments.

Professor Jaap Verweij (Erasmus University Medical Centre, The Netherlands), the EJC's clinical oncology editor and a co-editor of the special issue on RECIST, said: "This special issue is very important for the cancer community as the updated criteria will affect all clinicians who are running clinical cancer trials. RECIST 1.1 describes a standard approach to solid tumour measurement and definitions for objective assessment of change in tumour size for use in adult clinical trials."

Co-editor, Professor Elizabeth Eisenhauer (National Cancer Institute of Cancer, Ontario, Canada), stressed that the goal of developing RECIST 1.1 was to improve the consistency and standardisation of trials. "Drug development and clinical cancer research is a global enterprise. The more consistent we are in describing what we have seen
'/>"/>

Contact: Emma Mason (media enquiries only)
wordmason@mac.com
44-077-112-96986
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. New appropriate use criteria guide treatment of patients with heart blockage
2. Eligibility criteria contribute to racial disparities in hospice use
3. New Criteria Could Expand Number of Liver Transplant Candidates
4. How Patients Can Meet the Criteria for Insulin Pump Therapy
5. New Rhode Island Hospital study shows inadequate diagnostic criteria for eating disorders
6. Capital BlueCross CEO Says Meaningful Statewide Competition Must Be Key Criteria in Pennsylvanias Review of Proposed Highmark-IBC Merger
7. Landmark Articles Published by QualityMetric Scientists Report Improvements in Short Form Health Status Measures and Establish Criteria for Future Development
8. BMI criteria for obesity surgery should be lowered, UT Southwestern researchers suggest
9. Criteria Predict Womens 5-Year Risk for Fracture
10. New Test Criteria Spots Rheumatoid Arthritis Sooner
11. Health Care Leaders to Use New National Criteria for Patient-Centered Medical Home
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... 2014 The Advocator Group, LLC ... the American Foundation for Suicide Prevention’s (AFSP) Out of ... a not-for-profit organization that hosts hundreds of community walks ... events are used to help understand and prevent suicide ... relationships as well. , The Advocator Group shares ...
(Date:10/20/2014)... October 20, 2014 T.E.N., a ... firm, announced today that William H. Murray, renowned ... 2014 ISE® Luminary Leadership Award winner. Presented annually, ... of an outstanding leader and industry practitioner for ... in advancing the information security industry. , Formerly ...
(Date:10/20/2014)... JZ Fitness, an independently operated wellness ... programming, authorship, international lecturing and community wellness, created by ... release of the JZ Fitness nutrition app, available on ... thousands of individuals on nutrition, Jenn Zerling (“JZ”) has ... require calorie counting or cumbersome food logging. ...
(Date:10/20/2014)... CA (PRWEB) October 20, 2014 AttorneyOne.com, a ... the latest information from the FDA on Sit and ... October 10 not to purchase or use Sit and Slim ... and Slim II is promoted as weight loss product on ... removed from the market in 2010 for safety reasons, can ...
(Date:10/20/2014)... Succeed is proud to announce that they ranked in the ... Every Body Walk! campaign by Kaiser Permanente. Every ... to be more active outside of the workplace. This ... end of September, was a friendly competition between organizations across ... companies gave their staff pedometers and each day, for the ...
Breaking Medicine News(10 mins):Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Succeed Management Solutions, LLC Competes in Walking Challenge and Achieves 12th Place in Portland 2
... State University College of Nursing & Healthcare ... national Healthcare Innovation Challenge(R) ( http://healthcare.innovationchallenge.com ) in ... a firm that helps organizations run idea competitions. ... January 20 to May 1, 2009, features competition ...
... health care highly as part of efforts to stem ... reforming health care as one of the top priorities ... national survey conducted by researchers from the Kaiser Family ... Americans rank helping the newly unemployed afford health insurance ...
... reimburses patients and physicians who have been shortchanged ... American Medical Association (AMA), along with the Medical Society ... State Medical Association, claims victory with the settlement agreement ... The $350 million settlement marks the largest monetary settlement ...
... 15 The $800 million settlement that Eli,Lilly and Company ... settle civil False Claims,Act charges related to allegedly false or ... traced to the courageous stands taken by,employee whistleblowers, according to ... The company,s settlement with the federal government, which also ...
... The Procter & Gamble,Company (NYSE: PG ... -- Mariano Martin, (56), global customer ... 33 years of service. He will step,down from his ... focus on working,closely with his successor to ensure a ...
... 15 In a lawsuit pending in Wayne County,Circuit ... OmniCare, a,once-large HMO servicing Medicaid recipients, several major Detroit ... claim for $75 Million in,damages from United American Healthcare, ... In their filing, the Provider Creditors ...
Cached Medicine News:Health News:Arizona State University Nursing and Idea Crossing Partner to Conduct First National Healthcare Innovation Challenge 2Health News:Health provisions among public's top priorities for economic stimulus 2Health News:Health provisions among public's top priorities for economic stimulus 3Health News:Health provisions among public's top priorities for economic stimulus 4Health News:Health provisions among public's top priorities for economic stimulus 5Health News:AMA Claims Victory With Record Breaking Settlement in Case Against Insurer 2Health News:Whistleblowers' Complaints Lead Eli Lilly to Pay $800 Million to Settle Civil Medicaid Fraud Charges, According to Berg & Androphy 2Health News:Procter & Gamble Announces Organizational Changes 2Health News:Detroit Area Hospitals Seek $75 Million from United American HealthCare Arising out of its Management of the Liquidated OmniCare HMO 2
(Date:10/20/2014)... 2014  ResMed (NYSE: RMD ) ... Exchange program, a comprehensive suite of software and ... other health care providers. ResMed ... patient information. It integrates valuable sleep and respiratory ... management platforms with customers, in-house or third-party electronic ...
(Date:10/20/2014)... 20, 2014   BioNano Genomics announced today achievement ... to collect human data at 30X depth, sufficient for a ... new capability was established and demonstrated for the IrysChip TM ... System and will be rolled out to BioNano,s ... be showcasing this advancement at the American Society for ...
(Date:10/20/2014)...   Taiho Oncology, Inc. , a subsidiary ... ), announced that the U.S. Food and ... TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride), an ... treatment of refractory metastatic colorectal cancer (mCRC), and ... submission to the FDA. According to the American ...
Breaking Medicine Technology:ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 2Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 3Taiho Oncology, Inc. Receives FDA Fast Track Designation for TAS-102 as a Potential Treatment for Refractory Metastatic Colorectal Cancer 4
... 19, 2011 Enhanced Equity Fund (EEF), a healthcare-focused ... investment in MedTest DX, Inc. (MedTest), a medical diagnostic ... to purchase the chemistry diagnostics business from Polymedco, Inc. ... of EEF.  Terms were not disclosed. "EEF ...
... 2011 Wound Management Technologies, Inc., (OTCQB: WNDM | ... the publication of an interview of its President Deborah ... of interviews with CEOs and CFOs of publicly traded ... conducted by Lynn Fosse, Senior Editor, CEOCFOInterviews.com include why ...
Cached Medicine Technology:Enhanced Equity Fund and James White Invest in MedTest DX, Inc. 2WNDM President Interviewed; Discusses 2011 Outlook and Beyond 2WNDM President Interviewed; Discusses 2011 Outlook and Beyond 3
... Fast - Powerful g-Force for Fast and Optimal ... rpm (18,000 x g) Ideal for pelleting of ... Fits on crowded bench or in a cold ... aerosol-tight, autoclavable fixed-angle rotor Quiet operation ...
... EXD explosion-proof laboratory floor model centrifuge meets ... EXD is suitable for use in Class ... "atmospheres containing gasoline, petroleum, naphtha, benzol, lacquer, ... these specifications is so strict that the ...
Inquire...
... The XCell line of mini-cells ... simple sturdy and convenient. The tradition ... Mini-Cell. The incorporation of a gel ... rear wedge used on earlier models ...
Medicine Products: