Navigation Links
New concussion data: 2 biomarkers better than 1
Date:6/18/2013

Scientists are scrambling to gather data for the FDA to support the need for a blood test to diagnose brain injury in the United States. The University of Rochester Medical Center just added significant evidence by reporting in the Journal of Neurotrauma that it might be clinically useful to measure two brain biomarkers instead of one.

Jeffrey J. Bazarian, M.D., M.P.H., an associate professor of Emergency Medicine at URMC, believes he's the first to show that measuring a combination of two proteins released into the bloodstream after a head injury might be the best way to diagnose a mild traumatic brain injury. The protein S100B is already routinely used as screening tool in several countries in Europe and Asia.

But when researchers analyzed blood samples from 787 head injury patients (and compared them to 467 controls) at six upstate New York hospitals, including Strong Memorial, they discovered that a second protein called apoA-1 helps to most accurately classify the injury. Apoa-1 transports lipids and interacts with the blood-brain barrier in important ways following a concussion.

The study comes in the midst of a huge push to study every aspect of mild traumatic brain injury among war veterans, athletes, the elderly, and accident and assault victims. About 1.7 million cases are reported each year, although no objective diagnostic test exists.

Instead doctors must rely on judgment and observations, based on reports from the patient or witnesses, which have been shown to be notoriously inaccurate.

Heightened awareness of the long-term health consequences of head injuries prompted the U.S. Department of Defense to investment $26 million into research in 2010; the NFL invested $30 million in 2012. Bazarian has several studies in motion, with funding for the latest work provided by the New York State Department of Health, the Academic Health Center Consortium, and the Emergency Research Network of the Empire State (ERNIES).


'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. RSNA: Concussion Patients Show Alzheimer’s-like Brain Abnormalities
2. Concussion patients show Alzheimers-like brain abnormalities
3. New study shows most youth football player concussions occur during games, not practice
4. U of A research leads to enhanced CFL concussion guidelines
5. Study raises concerns that teen athletes continue to play with concussion symptoms
6. Kids Concussion Recovery Varies by Symptom Severity: Study
7. More severe concussion symptoms lead to longer recovery time
8. Study finds newspapers have changed coverage of ice hockey concussions over last quarter-century
9. Brain Injury Attorney Michael V. Kaplen will be a Panelist at the Brain Injury Symposium this July Speaking about Brain Injury and Concussions
10. Life with Teens Magazine Highlights the Steps to Prevent Teen Concussions
11. Notre Dame researchers scoring a win-win with novel set of concussion diagnostic tools
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... Mental health watchdog Citizens Commission ... Scientology and renowned professor of psychiatry Thomas Szasz, is continuing its protest against the ... of Death” exhibit in Atlanta, Georgia. The opening of the exhibit follows CCHR’s recent ...
(Date:5/24/2016)... ... May 24, 2016 , ... Boyd Industries, a leading supplier of ... a groundbreaking new product for pediatric dentistry , at AAPD 2016, the annual ... TX May 26-29. The Concealed Delivery Unit keeps dental hand pieces and other anxiety-provoking ...
(Date:5/24/2016)... ... 24, 2016 , ... The Radiosurgery Society (RSS), a non-profit ... recognizing five medical residents and students for their outstanding contributions to research in ... will be presented at the 2016 SRS/SBRT Scientific Meeting taking place June 16-18, ...
(Date:5/24/2016)... ... 2016 , ... As reported by MassGeneral.org, on May 8 – 9, 2016, ... States . The 64-year-old patient who received the transplant had undergone a partial penectomy ... a natural appearance, but also urinary and sexual function for the patient who has ...
(Date:5/24/2016)... ... May 24, 2016 , ... Harvard ... a licensing relationship that will deliver a new series of Q&A videos to ... the medical knowledge and expertise of Harvard Medical School faculty into brief videos ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... KONG , May 24, 2016 ... stent de doble terapia del mundo, introduce catéteres ... arteriovenosa. OrbusNeich, una compañía global especializada ... las vidas, ha expandido su cartera incluyendo productos ... balón JADE™ y Scoreflex™ PTA son los dispositivos ...
(Date:5/24/2016)... May 24, 2016 Open Access ... Clinical Neurophysiology  Elsevier , a world-leading ... services, today announced the launch of Clinical ... journal that focuses on clinical practice issues in clinical ... clinical series, normal values and didactic reviews. It is ...
(Date:5/24/2016)... , May 24, 2016 ... elkaar verbindt, zodat zij collectief patiënten kunnen behandelen, hun ... is het idee achter de nieuwe en revolutionaire MDLinking ... van de Nederlandse vaatchirurg dr. Hans Flu en oncologisch ... app, die inmiddels beschikbaar is, wordt op dinsdag 24 ...
Breaking Medicine Technology: