Navigation Links
New concussion data: 2 biomarkers better than 1
Date:6/18/2013

Scientists are scrambling to gather data for the FDA to support the need for a blood test to diagnose brain injury in the United States. The University of Rochester Medical Center just added significant evidence by reporting in the Journal of Neurotrauma that it might be clinically useful to measure two brain biomarkers instead of one.

Jeffrey J. Bazarian, M.D., M.P.H., an associate professor of Emergency Medicine at URMC, believes he's the first to show that measuring a combination of two proteins released into the bloodstream after a head injury might be the best way to diagnose a mild traumatic brain injury. The protein S100B is already routinely used as screening tool in several countries in Europe and Asia.

But when researchers analyzed blood samples from 787 head injury patients (and compared them to 467 controls) at six upstate New York hospitals, including Strong Memorial, they discovered that a second protein called apoA-1 helps to most accurately classify the injury. Apoa-1 transports lipids and interacts with the blood-brain barrier in important ways following a concussion.

The study comes in the midst of a huge push to study every aspect of mild traumatic brain injury among war veterans, athletes, the elderly, and accident and assault victims. About 1.7 million cases are reported each year, although no objective diagnostic test exists.

Instead doctors must rely on judgment and observations, based on reports from the patient or witnesses, which have been shown to be notoriously inaccurate.

Heightened awareness of the long-term health consequences of head injuries prompted the U.S. Department of Defense to investment $26 million into research in 2010; the NFL invested $30 million in 2012. Bazarian has several studies in motion, with funding for the latest work provided by the New York State Department of Health, the Academic Health Center Consortium, and the Emergency Research Network of the Empire State (ERNIES).


'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. RSNA: Concussion Patients Show Alzheimer’s-like Brain Abnormalities
2. Concussion patients show Alzheimers-like brain abnormalities
3. New study shows most youth football player concussions occur during games, not practice
4. U of A research leads to enhanced CFL concussion guidelines
5. Study raises concerns that teen athletes continue to play with concussion symptoms
6. Kids Concussion Recovery Varies by Symptom Severity: Study
7. More severe concussion symptoms lead to longer recovery time
8. Study finds newspapers have changed coverage of ice hockey concussions over last quarter-century
9. Brain Injury Attorney Michael V. Kaplen will be a Panelist at the Brain Injury Symposium this July Speaking about Brain Injury and Concussions
10. Life with Teens Magazine Highlights the Steps to Prevent Teen Concussions
11. Notre Dame researchers scoring a win-win with novel set of concussion diagnostic tools
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... Boca Raton, FL (PRWEB) , ... February 12, ... ... nation’s largest non-profit organization devoted exclusively to funding innovative lymphoma research and serving ... patient services – hosted over 250 members of South Florida’s philanthropic community at ...
(Date:2/12/2016)... ... February 12, 2016 , ... As a former television executive, owner Tal ... and no time to decompress, Rabinowitz found herself drawn to a casual meditation class ... impact on her life, implementing a 20-minute-per-day meditation practice with her team. After her ...
(Date:2/12/2016)... ... February 12, 2016 , ... Itopia, ... announced the integration of Clarity Intelligence Platform (CIP) into Cielo®, a discovery, migration ... business intelligence (BI) to their small and medium business (SMB) clients. ...
(Date:2/12/2016)... ... 12, 2016 , ... The Jones Agency, a family owned insurance company with ... a cooperative charity drive with the Tarrant Area Food Bank in the hopes of ... families in need, the Tarrant County Food Bank offers hope and security to the ...
(Date:2/12/2016)... ... February 12, 2016 , ... Donor Network West, the organ procurement organization that ... partnership with San Ramon Regional Medical Center. Under the collaboration, the first of its ... to accommodate a more certain time frame for donor families for the recovery of ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Holdings, Inc. (NASDAQ: IPHS ), a leading international producer ... will host a live conference call on Tuesday, February 23, ... and full year 2015 results. --> ... and full year results will be issued on Monday, February ... --> The conference call can be accessed ...
(Date:2/12/2016)... , Feb. 12, 2016   HeartWare International, ... conference call and webcast to discuss its financial results ... 2015, on Thursday, February 25, 2016 at 8:00 a.m. ... prior to the conference call and webcast.  On the ... financial results, highlights from the fourth quarter and business ...
(Date:2/12/2016)...  Memorial Hermann Health System has teamed up with ... bring a one-of-a-kind experience to pediatric patients at ... as 360-degree video and Google Cardboard, Howard was able ... giving the patients and their families an unexpected, and ... on video . Memorial Hermann IRONMAN ...
Breaking Medicine Technology: