Navigation Links
New concussion data: 2 biomarkers better than 1
Date:6/18/2013

Scientists are scrambling to gather data for the FDA to support the need for a blood test to diagnose brain injury in the United States. The University of Rochester Medical Center just added significant evidence by reporting in the Journal of Neurotrauma that it might be clinically useful to measure two brain biomarkers instead of one.

Jeffrey J. Bazarian, M.D., M.P.H., an associate professor of Emergency Medicine at URMC, believes he's the first to show that measuring a combination of two proteins released into the bloodstream after a head injury might be the best way to diagnose a mild traumatic brain injury. The protein S100B is already routinely used as screening tool in several countries in Europe and Asia.

But when researchers analyzed blood samples from 787 head injury patients (and compared them to 467 controls) at six upstate New York hospitals, including Strong Memorial, they discovered that a second protein called apoA-1 helps to most accurately classify the injury. Apoa-1 transports lipids and interacts with the blood-brain barrier in important ways following a concussion.

The study comes in the midst of a huge push to study every aspect of mild traumatic brain injury among war veterans, athletes, the elderly, and accident and assault victims. About 1.7 million cases are reported each year, although no objective diagnostic test exists.

Instead doctors must rely on judgment and observations, based on reports from the patient or witnesses, which have been shown to be notoriously inaccurate.

Heightened awareness of the long-term health consequences of head injuries prompted the U.S. Department of Defense to investment $26 million into research in 2010; the NFL invested $30 million in 2012. Bazarian has several studies in motion, with funding for the latest work provided by the New York State Department of Health, the Academic Health Center Consortium, and the Emergency Research Network of the Empire State (ERNIES).


'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. RSNA: Concussion Patients Show Alzheimer’s-like Brain Abnormalities
2. Concussion patients show Alzheimers-like brain abnormalities
3. New study shows most youth football player concussions occur during games, not practice
4. U of A research leads to enhanced CFL concussion guidelines
5. Study raises concerns that teen athletes continue to play with concussion symptoms
6. Kids Concussion Recovery Varies by Symptom Severity: Study
7. More severe concussion symptoms lead to longer recovery time
8. Study finds newspapers have changed coverage of ice hockey concussions over last quarter-century
9. Brain Injury Attorney Michael V. Kaplen will be a Panelist at the Brain Injury Symposium this July Speaking about Brain Injury and Concussions
10. Life with Teens Magazine Highlights the Steps to Prevent Teen Concussions
11. Notre Dame researchers scoring a win-win with novel set of concussion diagnostic tools
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... The International Association of Eating Disorders ... for the field of eating disorders, announces the opening of early registration for ... Florida at the Omni Resort at ChampionsGate. , The annual iaedp™ ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob ... sciatica in a new episode of "Success Files," which is an award-winning educational ... and investigates each subject in-depth with passion and integrity. , Sciatica occurs when ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... a leader in post-acute health care, have expanded their existing home health joint ... Health. , AccentCare has been operating a joint venture home health company with ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)...  Eli Lilly and Company (NYSE: LLY ... quarter of 2017 on Tuesday, October 24, 2017. Lilly ... with the investment community and media to further detail ... will begin at 9 a.m. Eastern time. Investors, media ... of the conference call through a link that will ...
(Date:10/2/2017)... Oct. 2, 2017 Halo Labs announces the European launch ... called the HORIZON at MIBio 2017 in Cambridge, U.K ... visible particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity ... novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: