Navigation Links
New clinical trial explores role of vitamin D in preventing esophageal cancer
Date:10/19/2010

CLEVELAND In a first-of-its-kind clinical trial, physicians at University Hospitals (UH) Case Medical Center who are Case Western Reserve University School of Medicine researchers are exploring the role of Vitamin D in preventing esophageal cancer. Principal Investigator Linda Cummings, MD, along with Amitabh Chak, MD, and Gregory Cooper, MD, from the UH Digestive Health Institute, is recruiting patients with Barrett's esophagus to measure the effects of Vitamin D on protein levels that may influence the risk of developing esophageal cancer.

"Vitamin D is being studied for its role in possibly reducing the risk of developing several types of cancer, such as colon, breast and prostate," says Dr. Cummings, a gastroenterologist with the UH Digestive Health Institute and Assistant Professor at Case Western Reserve University School of Medicine. "This novel study is the first-of-its-kind looking at Vitamin D's potential role in helping to prevent esophageal cancer." According to co-investigator Sanford Markowitz, MD, Ingalls Professor of Cancer Genetics at Case Western Reserve University School of Medicine and oncologist with UH Case Medical Center, the study "has the potential to make a highly important contribution to the medical management of Barrett's esophagus, which is becoming an ever increasing challenge."

The study is funded by the National Institutes of Health and American College of Gastroenterology through Case Western Reserve University School of Medicine and was awarded in July.

Over the last 30 years, there has been a dramatic rise in Barrett's esophagus, a change in the lining of the esophagus that is a precursor to esophageal cancer. In this study, researchers are examining if Vitamin D intake is linked to an increase in a protein called 15-PGDH (15-prostaglandin dehydrogenase), which may help prevent Barrett's from turning into cancer. Patients with Barrett's esophagus will take Vitamin D weekly (50,000 IU) for up for four months, and their levels of 15-PGDH will be measured.


'/>"/>

Contact: Alicia Reale
alicia.reale@uhhospitals.org
216-844-5158
University Hospitals Case Medical Center
Source:Eurekalert

Related medicine news :

1. Oklahoma clinical trial to test early detection technique for eye disease in premature infants
2. Clinical trials demonstrate effective weight loss strategies for obese and overweight adults
3. U-M receives NIH, FDA grant to study adaptive clinical trial designs
4. MJFF announces over $10 million in funding for clinical and pre-clinical PD research
5. Bioethics scholars fault requirement that all women in clinical drug trials use contraception
6. Clinical trial establishes catheter-based aortic valve replacement as new standard of care
7. New TB vaccine enters clinical testing
8. Aeras and Crucell announce Phase II clinical trial start in Kenya
9. First clinical trials successfully completed on potent new hepatitis C drug
10. Conference on the Future of Independent Academic Clinical Research in Europe
11. Preclinical inquiry into 1 mutation sheds light on addiction and a birth defect
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... ... ... An inventor from Cana, Va., wanted to fulfill the need for a device ... The patent-pending SAFETY STRAP FOR AMPUTEES improves accessibility. It eliminates discrimination. It is also ... a matter of minutes, or even seconds. The SAFETY STRAP FOR AMPUTEES is a ...
(Date:12/9/2016)... ... December 09, 2016 , ... The Pennsylvania Athletic Trainers’ Society ... the summer of 2016. The program was made possible by a Pennsylvania Department ... of Health and Human Services Administration. The broadcast, Use Your Head: Properly ...
(Date:12/8/2016)... ... December 08, 2016 , ... ZyDoc , ... Processing–Enabled and Conventional Data Capture Methods for Input to Electronic Health Records: A ... Results of the comparative usability study demonstrate that a dictation-based method (“NLP Entry”) ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... David ... with global law firm Greenberg Traurig, LLP, will speak at DeviceTalks West, Dec. 12, ... of the DeviceTalks series, and attorneys from the firm’s global Life Sciences & Medical ...
(Date:12/8/2016)... ... 2016 , ... STATEN ISLAND, N.Y., Nov. 24, 2016 — ... highest standards of trauma, maternity, cancer and chronic obstructive pulmonary disease (COPD) services ... Daniel Messina. , Among the recognitions, the American College of Surgeons' (ACS) named ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... STOUGHTON, Mass. , Dec. 9, 2016 ... device and supply chain solutions to alternate site health ... merger with First Choice Medical Supply ("First Choice"), a ... products servicing the skilled nursing and home health segments. ... MSD family. This compelling transaction will ...
(Date:12/9/2016)... 2016 Research and Markets has announced ... to 2021" report to their offering. ... Market growth can ... in the pharmaceutical and biotechnology industry and technological advancements like ... Emerging markets and growing research activities in toxicology and stem ...
(Date:12/9/2016)... Research and Markets has announced the addition of the "Global ... ... market to grow at a CAGR of 6.83% during the period ... growth prospects of the global travel vaccines market for 2016-2020. To ... the sales of various vaccines administered to actively immunize meningococcal disease, ...
Breaking Medicine Technology: