Navigation Links
New chemistry techniques improve hybrid scanner performance
Date:6/15/2009

TORONTOA new PET/MR imaging system has been developed that can successfully provide whole-body images of rats and other small animals, according to researchers at SNM's 56th Annual Meeting in Toronto. The new system could greatly improve imaging capabilities and advance research in many areas.

"Our system shows great promise because it is able to simultaneously provide the complementary strengths of PET and MRI in imaging rats and small animals," said Mitsuaki Tatsumi, associate professor of radiology at Osaka University Graduate School of Medicine and Medical Hospital, Osaka, Japan. "This ability opens up exciting new opportunities in research in terms of increased understanding of kinetics, biodistribution of radiopharmaceuticals and, eventually, disease characteristics and physiological processes. Next steps include imaging body tumors in rats or mice and developing PET/MRI systems that can image people."

A combined PET/MRI system delivers specific molecular information related to cell surface reactors, enzymes and gene expression that PET provides as well as important anatomical data, soft-tissue contrast and information about perfusion and permeability shown in MRIat the same time.

The new combined PET/MRI system is a step forward from previous combined systems because it can image the bodies of rats and mice rather than just the brains. The system consists of depth-of-interaction block detectors and a permanent magnet for MRI.

In the study, researchers injected rats with the radionuclide C-11 methionine for PET imaging and with Gadoxetate for contrast MRI imaging. Simultaneous PET and MR imaging was performed from head to abdomen. PET, MR and co-registered fusion images were then evaluated for image quality.

The simultaneous PET/MRI system provided quality images in spite of the short half-life of C-11. The images showed excellent mapping of the liver and kidneys. C-11 methionine is known to accumulate in the pancreas, but it would have been difficult to image without clear mapping MR images. The use of Gadoextate as a contrast agent enhanced the power of the integrated PET/MRI system.


'/>"/>

Contact: Amy Shaw
ashaw@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Related medicine news :

1. Genes, brain chemistry may dictate nicotine cravings, says CU-Boulder study
2. Histochemistry is the golden standard in the diagnosis of carcinosarcomas
3. ThalesNano Inc. and the Christian Doppler Laboratory for Microwave Chemistry in Graz, Austria Collaborate on Flow Chemistry Technologies
4. Job picture for 2006 chemistry grads reasonably good, C&EN reports
5. SAFC Pharma Expands Its Pharmorphix Solid State Chemistry Services
6. Lab on a chip mimics brain chemistry
7. 11 Pharmaceutical Titans Headline Chemistry Outsourcing Conference Program in September in New Jersey
8. UCR chemists use green chemistry to produce amines, chemical compounds used widely in industry
9. 1 step closer to green chemistry and improved pharmaceuticals
10. MS drug development agreement based on WEHIs medicinal chemistry
11. Dr. Richard M. Soll Joined WuXi PharmaTech (NYSE: WX) as VP of Medicinal Chemistry
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media ... give their videos a whole new perspective by using the title layers in ... Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... ... 25, 2016 , ... First Choice Emergency Room , the largest network ... the Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased ... location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 One of Australia,s successful ... of a new biotechnology company, Noxopharm Limited [ABN 50 608 966 ... and to list on the ASX. Noxopharm is a ... enter a Phase 1 clinical study later this year. ... of the biggest problems facing cancer patients - the ability of ...
(Date:6/26/2016)... 2016 Jazz Pharmaceuticals plc (Nasdaq: ... Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ("HSR"), ... Inc. ("Celator"; Nasdaq: CPXX ) expired effective ... As previously announced on May 31, 2016, ... agreement under which Jazz Pharmaceuticals has commenced a tender ...
(Date:6/26/2016)... -- VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) reported today ... to build a strong and stable market for trading ... the OTC Markets-pink current trading platform. Explains ... seeing an anomaly in market trading activities that may ... Company, but shareholders and market players as well. I ...
Breaking Medicine Technology: