Navigation Links
New chemistry techniques improve hybrid scanner performance
Date:6/15/2009

TORONTOA new PET/MR imaging system has been developed that can successfully provide whole-body images of rats and other small animals, according to researchers at SNM's 56th Annual Meeting in Toronto. The new system could greatly improve imaging capabilities and advance research in many areas.

"Our system shows great promise because it is able to simultaneously provide the complementary strengths of PET and MRI in imaging rats and small animals," said Mitsuaki Tatsumi, associate professor of radiology at Osaka University Graduate School of Medicine and Medical Hospital, Osaka, Japan. "This ability opens up exciting new opportunities in research in terms of increased understanding of kinetics, biodistribution of radiopharmaceuticals and, eventually, disease characteristics and physiological processes. Next steps include imaging body tumors in rats or mice and developing PET/MRI systems that can image people."

A combined PET/MRI system delivers specific molecular information related to cell surface reactors, enzymes and gene expression that PET provides as well as important anatomical data, soft-tissue contrast and information about perfusion and permeability shown in MRIat the same time.

The new combined PET/MRI system is a step forward from previous combined systems because it can image the bodies of rats and mice rather than just the brains. The system consists of depth-of-interaction block detectors and a permanent magnet for MRI.

In the study, researchers injected rats with the radionuclide C-11 methionine for PET imaging and with Gadoxetate for contrast MRI imaging. Simultaneous PET and MR imaging was performed from head to abdomen. PET, MR and co-registered fusion images were then evaluated for image quality.

The simultaneous PET/MRI system provided quality images in spite of the short half-life of C-11. The images showed excellent mapping of the liver and kidneys. C-11 methionine is known to accumulate in the pancreas, but it would have been difficult to image without clear mapping MR images. The use of Gadoextate as a contrast agent enhanced the power of the integrated PET/MRI system.


'/>"/>

Contact: Amy Shaw
ashaw@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Related medicine news :

1. Genes, brain chemistry may dictate nicotine cravings, says CU-Boulder study
2. Histochemistry is the golden standard in the diagnosis of carcinosarcomas
3. ThalesNano Inc. and the Christian Doppler Laboratory for Microwave Chemistry in Graz, Austria Collaborate on Flow Chemistry Technologies
4. Job picture for 2006 chemistry grads reasonably good, C&EN reports
5. SAFC Pharma Expands Its Pharmorphix Solid State Chemistry Services
6. Lab on a chip mimics brain chemistry
7. 11 Pharmaceutical Titans Headline Chemistry Outsourcing Conference Program in September in New Jersey
8. UCR chemists use green chemistry to produce amines, chemical compounds used widely in industry
9. 1 step closer to green chemistry and improved pharmaceuticals
10. MS drug development agreement based on WEHIs medicinal chemistry
11. Dr. Richard M. Soll Joined WuXi PharmaTech (NYSE: WX) as VP of Medicinal Chemistry
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... ... January 24, 2017 , ... OMI Industries, a worldwide ... a distribution partnership with Byers Scientific & Manufacturing , a leading designer, ... the agreement, OMI Industries formulated a special version of Ecosorb® for Byers Scientific ...
(Date:1/24/2017)... ... ... This Saturday, January 28, the BCFA presents more than 20 local performances including Chinese ... Yifan Zhou, Mara McClain & Sarah Nordlund Dennis. Local chefs and restaurants provide a ... Chinese games, crafts & more. Festivities begin at 11:00 am and end at 2:30 ...
(Date:1/24/2017)... ... January 24, 2017 , ... The results from the ... everyone and particularly good news for prostate cancer patients: incidents of cancer is down ... to the report the cancer death rate has dropped from its peak of 215.1 ...
(Date:1/24/2017)... ... January 24, 2017 , ... Today, Taza ... latest award-winning bottles, designed specifically to optimize the drinking experience for K-Cup coffee, ... renowned for introducing the world’s first untouched bottled water purposed exclusively for creating ...
(Date:1/24/2017)... ... January 24, 2017 , ... “Choosing ... like finances, friendship, marriage, leadership, gossip, prostitution, adultery, anger, and common sense. ... Dr. Judith Coats and Dr. David Coats. In September of 1983, they flew ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)...  In a major study released this weekend ... 1 ( http://www.multivu.com/players/English/7899551-nephrocheck-test-acute-kidney-injury-outcomes/ ), Astute ... identified patients at high risk of Acute Kidney ... randomized control trial led by Alexander Zarbock ... institution,s standard of care or a treatment per ...
(Date:1/24/2017)... Jan. 24, 2017 When tragedy strikes, victims often can,t ... what conditions they have, and who back home is wondering about ... ones informed about the safety of their family and friends, while ... victims in times of crisis. ... If you find yourself or your family in one ...
(Date:1/24/2017)... 2017 Market Research Future has a half cooked research ... market for Plastic Surgery & Integumentary System is growing rapidly and ... forecasted period. Market Highlights ... Global Plastic Surgery & Integumentary System Market has ... market will reach high growth figures and thriving in the coming ...
Breaking Medicine Technology: