Navigation Links
New chemical probe provides tool to investigate role of malignant brain tumor domains
Date:3/1/2013

ysfunction within signaling pathways. In the last five years, chemical probe development has allowed researchers to make fundamental observations of the role of these pathways in cancer development, as well as pointing to potential targets for new therapies. Each of the complex interactions within the signaling pathways represents a potential point where a therapy can be applied, and the probes allow researchers to interact with these processes at the molecular level and observe the overall effect of their perturbation on the disease state.

In a 2008 Nature Chemical Biology commentary, Dr. Frye outlined the qualities that make a good chemical probe. To Frye, a good chemical probe must be highly selective to enable specific questions to be asked and it must function as well in a cell as in the test tube, providing clear quantitative data with a well understood mechanism of action in either situation. It also must be available to all academic researchers without restrictions on its use, a criteria that the L3MBTL3 probe fulfills through the Frye lab's commitment to provide researchers with the probe free of charge on request and UNC1215 is already available through commercial vendors as well.


'/>"/>

Contact: William Davis
william_davis@med.unc.edu
919-962-3405
University of North Carolina Health Care
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Foods Might Serve Up High Levels of Chemicals Found in Plastics
2. American Chemical Society podcast: New super-nutritious puffed rice for breakfast cereals, snacks
3. Plastics Chemical BPA Common in Preemie ICU: Study
4. Flame Retardant Chemicals Market growing at a CAGR of 6.9% & to reach $7,131.9 Million by 2017 - New Report by MarketsandMarkets
5. Chemicals in Cookware, Carpets May Raise Arthritis Risk in Women
6. Chemicals From Antibacterial Products Found in Minnesota Lakes
7. Test for hormone-disrupting chemicals gets global seal of approval
8. Could Chemical in Dishware Raise Your Risk for Kidney Stones?
9. 2013 economic outlook for global chemical industry
10. New American Chemical Society podcast: Leaves of carob tree fight food-poisoning bacteria
11. New treatment could combat deadly chemical agents
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New chemical probe provides tool to investigate role of malignant brain tumor domains
(Date:1/22/2015)... Lynchburg, Va. (PRWEB) January 22, 2015 Liberty ... Health Counseling (M.A.) program from the Council for ... The program, part of Liberty’s Center for Counseling & ... Hawkins, founding dean of the university’s new School of Behavioral ...
(Date:1/22/2015)... 22, 2015 Woodloch Pines, an all-inclusive ... selected by TripAdvisor as the number one best large hotel ... in the world for their annual Travelers’ Choice Awards. ... . The website is home to millions of unbiased and ...
(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
(Date:1/22/2015)... Minn. (PRWEB) January 22, 2015 Blue Cross ... those Minnesotans who exemplify what it means to “Live Fearless.” ... chance for people to share their stories about how they ... or simply inspired others by living in the moment. By ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Juvent Sports ... at the 2015 PGA Merchandise Show to bestow a ... incredible female amateur golfer, Arlene McKitrick. The award commemorated ... amateur golf tournament win. She won her first amateur ...
Breaking Medicine News(10 mins):Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3
... KeepEmCookin.com highlighted in June 2009 issue of Pregnancy BALTIMORE, ... its "Website We Can,t Live Without" for June 2009.The ... bed rest and preterm labor that is current, concise, ... up-to-date and reliable, and then gives women a place ...
... Health Care Costs And Prevents 164,000 Emergency Room ... 20 Funding for poison control services has ... Beginning in September of 2009, California will become ... emergency poison control services for residents or medical ...
... Orasi Medical, Inc. announced today that it has completed ... use this capital to expand the development and use ... markets. Pharmaceutical companies will use this test to determine ... diseases. Orasi is currently in discussions with several pharmaceutical ...
... to Urge Families to Take Action against Atherosclerosis , ... AZN ) today kicks off the 2009 JUNTOS CONTRA ... state-of-the-art, multisensory, motion simulator that helps people visualize atherosclerosis ... For a second year in a row, AstraZeneca has ...
... nearly $2.4 million over the last eight yearsSAN ... Bros. is proud to announce that the Company, ... $339,537 to benefit the American Heart Association. Since ... for the American Heart Association.(Photo: http://www.newscom.com/cgi-bin/prnh/20090520/LA20346 ...
... US Farms, Inc. (Pink Sheets: USFM), announced today ... Products Association. Founded in 1936, the Natural Products Association ... representing more than 10,000 retailers, manufacturers, wholesalers and distributors ... aids. The Natural Products Association,s mission is to advocate ...
Cached Medicine News:Health News:Pregnancy Magazine Names KeepEmCookin.com its 'Website We Can't Live Without' 2Health News:Governor Eliminates California's Poison Control Service 2Health News:AstraZeneca, the National Alliance for Hispanic Health and LULAC Join Forces to Promote Needed Heart Health Education in Hispanic Communities 2Health News:AstraZeneca, the National Alliance for Hispanic Health and LULAC Join Forces to Promote Needed Heart Health Education in Hispanic Communities 3Health News:AstraZeneca, the National Alliance for Hispanic Health and LULAC Join Forces to Promote Needed Heart Health Education in Hispanic Communities 4Health News:AstraZeneca, the National Alliance for Hispanic Health and LULAC Join Forces to Promote Needed Heart Health Education in Hispanic Communities 5Health News:Stater Bros. Raises $339,537 for American Heart Association 2Health News:Stater Bros. Raises $339,537 for American Heart Association 3Health News:US Farms, Inc. Announces Membership to Natural Products Association 2
(Date:1/23/2015)...  iMD Companies, Inc. (ICBU) has repositioned itself as a holding ... a foothold in the hydroponic, hemp and medical marijuana sectors. ... in the sector, and recently partnering with the Chippewa Tribe ... medical marijuana, iMD is committing to bring its vision to ...
(Date:1/23/2015)... MONMOUTH JUNCTION, N.J. , Jan. 23, 2015 ... immunotherapy company commercializing its CytoSorb® extracorporeal cytokine adsorber ... surgery patients, announced the receipt of $385,642, net ... approved participant of the Technology Business Tax Certificate ...
(Date:1/23/2015)... Tianyin Pharmaceutical Inc. (NYSE Amex: TPI ), ... sale of patented biopharmaceutical medicine, modernized traditional Chinese medicine ... announced the business and development progress at its Jiangchuan ... the September 2014 JCM application (No. 51268) for the ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4
... Modulator Administered in Dual Cord Blood Transplant for Hematologic MalignancyLA ... announced today that the first patient has been ... small molecule Stem Cell Modulator (SCM) designed to increase hematopoietic ... key pathways that guide cell fate. The study, which ...
... delivers Germ-Free cleaning, extending life, efficiency and healthiness of ... are almost neurotic about washing their hands and using ... at their computer and put their hands all over ... ground for these persistent little bugs, which are known ...
Cached Medicine Technology:Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 2Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 3Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 4GreenBytes Wards Off Germs and Costly Computer Repairs 2GreenBytes Wards Off Germs and Costly Computer Repairs 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: