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New book presents comprehensive survey of research into the molecular basis of aging
Date:12/7/2007

COLD SPRING HARBOR, N.Y. In recent years, significant progress has been made in aging-related research. In an authoritative new book published by Cold Spring Harbor Laboratory Press (www.cshlpress.com), leading scientists present recent research advances on the molecular basis of aging, such as the identification of genes that regulate aging and the relationship between diet and aging. They also discuss the potential for developing new drugs to regulate aging and ameliorate aging-related diseases, including Alzheimers disease and cancer.

The book, entitled Molecular Biology of Aging (www.cshlpress.com/link/molebioage.htm), is the first to comprehensively cover this field in a single volume. It is an essential source of information for researchers, clinicians, and anyone interested in the field of biogerontology.

Molecular Biology of Aging was edited by three leading experts in the field, Lenny Guarente, Linda Partridge, and Douglas Wallace, each of whom contributed chapters to the book.

Guarentes chapter focuses on sirtuins, which are enzymes that function as critical regulators of aging-related processes in many organisms. He recently authored the popular book Ageless Quest (www.cshlpress.com/link/ageless.htm), also published by Cold Spring Harbor Laboratory Press, in which he provides a personal account of his pursuit of a cure for aging.

Partridges chapter explores the genetics, evolution, and physiology of aging using Drosophila as a model. Her work has shown that single-gene mutations can extend lifespans, and has uncovered physiological trade-offs related to longevity, such as reproduction rate and dietary intake.

Molecular Biology of Aging begins with Wallaces chapter, which discusses the role of mitochondr
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Contact: Ingrid Benirschke
benirsch@cshl.edu
619-275-6021
Cold Spring Harbor Laboratory  
Source:Eurekalert

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